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AFP Mouse mAb

    应用:
  • CLIA
  • Detection Antibody
  • ELISA
  • 宿主种属: 小鼠(Mouse)
  • 种属反应性: 人(Human)
  • 亚型: Mouse IgG1
  • 克隆号: 2H3
  • 偶联: Unconjugated
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货号 (SKU) 包装规格 是否现货 价格 数量
Ab007318-10μg
10μg 现货 Stock Image
Ab007318-50μg
50μg 现货 Stock Image
Ab007318-100μg
100μg 现货 Stock Image
Ab007318-1mg
1mg 现货 Stock Image

基本信息

产品名称 AFP Mouse mAb
别名 AFP 小鼠 mAb | 甲胎蛋白抗体 | 甲胎蛋白重组单克隆抗体 | AFP抗体 | AFP重组单克隆抗体
英文别名 Alpha-1-fetoprotein | Alpha-fetoglobulin
规格或纯度 无载体, ExactAb™, 无叠氮钠, 已验证, 见COA
生化机理 Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties.
宿主种属 小鼠(Mouse)
特异性 AFP
应用 ELISA,CLIA
种属反应性 人(Human)
免疫原 Native protein
偶联 Unconjugated

产品属性

抗体类型 Primary antibody
克隆类型 单克隆抗体
克隆号 2H3
Format Whole IgG
亚型 IgG1
SDS-PAGE 150 kDa
纯化方法 Affinity purified
配对抗体 [Ab007317] Recombinant AFP Antibody as Capture antibody in ELISA, CLIA.
来源 Hybridoma supernatant
物理外观 Liquid
储存缓冲液 10mM PB, 150mM NaCl, 0.1% ProClin 300, pH 7.4
防腐剂 0.1% ProClin 300
浓度 见COA
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 长期储存-20℃(36个月);收货后建议分装,避免反复冻融。
分子类型 抗体

关联靶点(人)

AFP Tbio 甲胎蛋白(Alpha-fetoprotein) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

图片

Relevance of detection results between aladdin Antibody Pair (Ab007317 & Ab007318) and Roche in CLIA
· Capture antibody: Recombinant AFP Antibody (Ab007317) at 1.0 μg/mL.
· Detection antibody: AFP Mouse mAb (Ab007318) at 1.0 μg/mL.
· Linear Range: 0.5-1000 IU/mL, R² ≥ 0.99.

应用

应用名称 稀释比例
ELISA

1 μg/mL

CLIA

1 μg/mL

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
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找到7个结果

批号(Lot Number) 证书类型 货号
ZJ25F1028795 分析证书 Ab007318
ZJ25F0926492 分析证书 Ab007318
ZJ25F0926491 分析证书 Ab007318
ZJ25F0926490 分析证书 Ab007318
ZJ24F1011956 分析证书 Ab007318
ZJ23F0500255 分析证书 Ab007318
ZJ23F0500258 分析证书 Ab007318

引用文献

1. Thomas R Burkard,Melanie Planyavsky,Ines Kaupe,Florian P Breitwieser,Tilmann Bürckstümmer,Keiryn L Bennett,Giulio Superti-Furga,Jacques Colinge.  (2011-01-29)  Initial characterization of the human central proteome..  BMC systems biology,  (17-17).  [PMID:21269460]
2. Yachnin, S S, Hsu, R R, Heinrikson, R L RL and Miller, J B JB..  (1977)  Studies on human alpha-fetoprotein. Isolation and characterization of monomeric and polymeric forms and amino-terminal sequence analysis..  Biochimica et biophysica acta,  (23): [PMID:70228]
3. Aoyagi, Y Y, Ikenaka, T T and Ichida, F F..  (1977)  Comparative chemical structures of human alpha-fetoproteins from fetal serum and from ascites fluid of a patient with hepatoma..  Cancer research,  [PMID:71198]
4. Aoyagi, Y Y, Ikenaka, T T and Ichida, F F..  (1978)  Copper(II)-binding ability of human alpha-fetoprotein..  Cancer research,  [PMID:80265]
5. Aoyagi, Y Y, Ikenaka, T T and Ichida, F F..  (1979)  alpha-Fetoprotein as a carrier protein in plasma and its bilirubin-binding ability..  Cancer research,  [PMID:89900]
6. Pucci, P P and 6 more authors..  (1991)  Human alpha-fetoprotein primary structure: a mass spectrometric study..  Biochemistry,  (21): [PMID:1709810]
7. Liu, M C MC, Yu, S S, Sy, J J, Redman, C M CM and Lipmann, F F..  (1985)  Tyrosine sulfation of proteins from the human hepatoma cell line HepG2..  Proceedings of the National Academy of Sciences of the United States of America,  [PMID:2414772]
8. Gibbs, P E PE, Zielinski, R R, Boyd, C C and Dugaiczyk, A A..  (1987)  Structure, polymorphism, and novel repeated DNA elements revealed by a complete sequence of the human alpha-fetoprotein gene..  Biochemistry,  (10): [PMID:2436661]
9. Sakai, M M and 5 more authors..  (1985)  The human alpha-fetoprotein gene. Sequence organization and the 5' flanking region..  The Journal of biological chemistry,  (25): [PMID:2580830]
10. Ruoslahti, E E and 5 more authors..  (1974)  Alpha fetoprotein: structure and expression in man and inbred mouse strains under normal conditions and liver injury..  Johns Hopkins medical journal. Supplement,  [PMID:4138095]
11. Beattie, W G WG and Dugaiczyk, A A..  (1982)  Structure and evolution of human alpha-fetoprotein deduced from partial sequence of cloned cDNA..  Gene,  [PMID:6187626]
12. Morinaga, T T, Sakai, M M, Wegmann, T G TG and Tamaoki, T T..  (1983)  Primary structures of human alpha-fetoprotein and its mRNA..  Proceedings of the National Academy of Sciences of the United States of America,  [PMID:6192439]
13. McVey, J H JH and 6 more authors..  (1993)  A G-->A substitution in an HNF I binding site in the human alpha-fetoprotein gene is associated with hereditary persistence of alpha-fetoprotein (HPAFP)..  Human molecular genetics,  [PMID:7684942]
14. Sharony, Reuven R, Zadik, Idit I and Parvari, Ruti R..  (2004)  Congenital deficiency of alpha feto-protein..  European journal of human genetics : EJHG,  [PMID:15280901]
15. Petit, François M FM and 10 more authors..  (2009)  A new mutation in the AFP gene responsible for a total absence of alpha feto-protein on second trimester maternal serum screening for Down syndrome..  European journal of human genetics : EJHG,  [PMID:18854864]
16. Tagliabracci, Vincent S VS and 14 more authors..  (2015)  A Single Kinase Generates the Majority of the Secreted Phosphoproteome..  Cell,  (18): [PMID:26091039]

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