This is a demo store. No orders will be fulfilled.

 
Call +1 (833) 552-7181 or Contact us
Toggle Nav
My Cart
Search
Advanced Search
Menu
Account
Settings
྾
main product photo

PP2A-alpha Antibody - Primary antibody, specific to PP2A-alpha, Rabbit IgG

COA COA
    Application:
  • IHC
  • WB
  • Host species: Rabbit
  • Reactive species: Human
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab122718
Grouped product items
SKU Size
Availability
 Price Qty
Ab122718-10μl
10μl
2
$69.90
Ab122718-50μl
50μl
1
$189.90
Ab122718-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$289.90
Ab122718-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,309.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

pAb; Rabbit anti Human PP2A-alpha Antibody; WB, IHC; Unconjugated

View related series
Click to view target information: PPP2CA
Accession#:P67775 (2) Gene ID:5515 (2) PP2A-alpha (1) PPP2CA (2)

Basic Description

Product Name PP2A-alpha Antibody - Primary antibody, specific to PP2A-alpha, Rabbit IgG
Synonyms PP2A alpha antibody | PP2A-alpha antibody | PP2AA_HUMAN antibody | PP2Aalpha antibody | PP2Ac antibody | PP2CA antibody | PP2Calpha antibody | PPP2CA antibody | Protein phosphatase 2 (formerly 2A) catalytic subunit alpha isoform antibody | Protein phospha
Specifications & Purity ExactAb™, Validated, Carrier Free, 2.0 mg/mL
Host species Rabbit
Specificity PP2A-alpha
Immunogen A KLH conjugated synthetic peptide from the C-terminal region of human PP2A alpha (AA 274-304).
Positive Control WB: A431, K562, NIH/3T3 and C6 cell lysates. IHC: Human cancer tissue.
Conjugation Unconjugated
Grade Carrier Free, ExactAb™, Validated
Product Description

Rabbit anti Human PP2A-alpha Antibody, Polyclonal, could be used for WB, IHC and so on.
Application:
WB: 1/1000
IHC: 1/100-1/500
Protein Function:
PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Dephosphorylates SV40 large T antigen, preferentially on serine residues 120, 123, 677, and perhaps 679. The C subunit was most active, followed by the AC form, which was more active than the ABC form, and activity of all three forms was strongly stimulated by manganese, and to a lesser extent by magnesium. Dephosphorylation by the AC form, but not C or ABC form is inhibited by small T antigen.

Product Properties

Isotype Rabbit IgG
SDS-PAGE 150 kDa
Purification Method Saturated ammonium sulfate precipitation
Shape Liquid
Concentration 2.0 mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4℃ short term (2 weeks). Store at -20℃ long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

PPP2CA Tchem Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

PP2A-alpha Antibody (Ab122718) - Western Blot
All lanes: PP2A-alpha Antibody (Ab122718) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 36 kDa
Observed band size: 35 kDa
Exposure time: 48.1 s

PP2A-alpha Antibody (Ab122718) - IHC
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of PP2A-alpha Antibody (Ab122718) for immunohistochemistry; clinical relevance has not been evaluated. HC = hepatocarcinoma.

Application

Application Dilution info
IHC

1/100-1/500
WB

1/1000

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ24F0303423 Certificate of Analysis Mar 20, 2024 Ab122718
ZJ24F0303424 Certificate of Analysis Mar 20, 2024 Ab122718

Related Products

  1. Goat Anti-Rabbit IgG H&L (AF488)
    Goat Anti-Rabbit IgG H&L (AF488)

    Starting at $198.90

    Wish List Compare
  2. Goat Anti-Rabbit IgG H&L (Biotin)
    Goat Anti-Rabbit IgG H&L (Biotin)

    Starting at $19.90

    Wish List Compare
  3. Goat Anti-Rabbit IgG H&L Antibody
    Goat Anti-Rabbit IgG H&L Antibody

    Starting at $134.90

    Wish List Compare
  4. Goat Anti-Rabbit IgG H&L (Cy5)
    Goat Anti-Rabbit IgG H&L (Cy5)

    Starting at $29.90

    Wish List Compare
  5. Goat Anti-Rabbit IgG H&L (HRP)
    Goat Anti-Rabbit IgG H&L (HRP)

    Starting at $19.90

    Wish List Compare
  6. Goat Anti-Rabbit IgG H&L (HRP)
    Goat Anti-Rabbit IgG H&L (HRP)

    Starting at $25.90

    Wish List Compare
  7. Goat Anti-Rabbit IgG H&L (AF647)
    Goat Anti-Rabbit IgG H&L (AF647)

    Starting at $19.90

    Wish List Compare
  8. Goat Anti-Rabbit IgG H&L (AF555)
    Goat Anti-Rabbit IgG H&L (AF555)

    Starting at $15.90

    Wish List Compare
  9. Goat Anti-Rabbit IgG H&L Antibody
    Goat Anti-Rabbit IgG H&L Antibody

    Starting at $117.90

    Wish List Compare
  10. Goat Anti-Rabbit IgG H&L (AF405)
    Goat Anti-Rabbit IgG H&L (AF405)

    Starting at $16.90

    Wish List Compare
  11. Donkey Anti-Rabbit IgG H&L (AF647)
    Donkey Anti-Rabbit IgG H&L (AF647)

    Starting at $69.90

    Wish List Compare
  12. Goat Anti-Rabbit IgG H&L (AF546)
    Goat Anti-Rabbit IgG H&L (AF546)

    Starting at $39.90

    Wish List Compare
  13. Goat Anti-Rabbit IgG H&L (APC)
    Goat Anti-Rabbit IgG H&L (APC)

    Starting at $109.90

    Wish List Compare
  14. Donkey Anti-Rabbit IgG H&L (Biotin)
    Donkey Anti-Rabbit IgG H&L (Biotin)

    Starting at $57.90

    Wish List Compare
  15. Goat Anti-Rabbit IgG H&L (AF405)
    Goat Anti-Rabbit IgG H&L (AF405)

    Starting at $87.90

    Wish List Compare
  16. Goat Anti-Rabbit IgG H&L (TRITC)
    Goat Anti-Rabbit IgG H&L (TRITC)

    Starting at $19.90

    Wish List Compare
  17. Goat Anti-Rabbit IgG H&L (FITC)
    Goat Anti-Rabbit IgG H&L (FITC)

    Starting at $25.90

    Wish List Compare
  18. Goat Anti-Rabbit IgG H&L (TRITC)
    Goat Anti-Rabbit IgG H&L (TRITC)

    Starting at $19.90

    Wish List Compare
  19. Goat Anti-Rabbit IgG H&L (AF594)
    Goat Anti-Rabbit IgG H&L (AF594)

    Starting at $87.90

    Wish List Compare
  20. Goat Anti-Rabbit IgG H&L (AF700)
    Goat Anti-Rabbit IgG H&L (AF700)

    Starting at $39.90

    Wish List Compare

Solution Calculators

Reviews

Customer Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.

Privacy Policy Website Terms of Use Return policy Terms and Conditions of Sale Cookie Policy Sales Policy
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
Copyright © 2023-present Aladdin Scientific Corp . All rights reserved.