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Radionuclide-Drug Conjugates (RDCs)

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  1. Diethylenetriaminepentaacetic acid dianhydride
      Grade & Purity: 
    • ≥98%
    Cas Number: 23911-26-4
    Formula:  C14H19N3O8        Molecular Weight: 357.32
    IUPAC Name:  2-[bis[2-(2,6-dioxomorpholin-4-yl)ethyl]amino]acetic acid
    SMILES:  C1C(=O)OC(=O)CN1CCN(CCN2CC(=O)OC(=O)C2)CC(=O)O
    InChIKey: RAZLJUXJEOEYAM-UHFFFAOYSA-N
    InChI:  InChI=1S/C14H19N3O8/c18-10(19)5-15(1-3-16-6-11(20)24-12(21)7-16)2-4-17-8-13(22)25-14(23)9-17/h1-9H2,(H,18,19)
    Synonyms: NSC-125674 | NSC379317 | NSC-379317 | Uric acid, >=99%, crystalline | Glycine, N,N-bis(2-(2,6-dioxo-4-morpholinyl)eth...
  2. Trastuzumab (anti-ERBB2)
      Grade & Purity: 
    • ≥95%
    • ~21mg/ml(en tampón,pH6.0).
    Associated targets:  ERBB2
      Isotype: Human IgG1    
    Cas Number: 180288-69-1
    Formula:  C6470H10012N1726O2013S42        Molecular Weight: 145531.50
    IUPAC Name:  2,8-diamino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
    SMILES:  C(C1C(C(C(O1)N2C3=C(C(=O)NC(=N3)N)N=C2N)O)O)O
    InChIKey: FNXPTCITVCRFRK-UMMCILCDSA-N
    InChI:  InChI=1S/C10H14N6O5/c11-9-14-6-3(7(20)15-9)13-10(12)16(6)8-5(19)4(18)2(1-17)21-8/h2,4-5,8,17-19H,1H2,(H2,12,13)(H3,11,14,15,20)/t2-,4-,5-,8-/m1/s1
    Synonyms: 8-Aminoguanosine, >=98% (HPLC) | SHO2CA1BRO | Guanosine, 8-amino- | SCHEMBL483333 | 2,8-diamino-9-[(2R,3R,4S,5R)-3,4-...
  3. Tri-tert-butyl 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetate
      Grade & Purity: 
    • ≥97%
    Cas Number: 137076-54-1        Compound CID:  11606627
    Formula:  C28H52N4O8        Molecular Weight: 572.74
    IUPAC Name:  2-[4,7,10-tris[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]-1,4,7,10-tetrazacyclododec-1-yl]acetic acid
    SMILES:  CC(C)(C)OC(=O)CN1CCN(CCN(CCN(CC1)CC(=O)OC(C)(C)C)CC(=O)OC(C)(C)C)CC(=O)O
    InChIKey: RVUXZXMKYMSWOM-UHFFFAOYSA-N
    InChI:  InChI=1S/C28H52N4O8/c1-26(2,3)38-23(35)19-30-12-10-29(18-22(33)34)11-13-31(20-24(36)39-27(4,5)6)15-17-32(16-14-30)21-25(37)40-28(7,8)9/h10-21H2,1-9H3,show more
    Synonyms: 2-(4,7,10-TRIS(2-TERT-BUTOXY-2-OXOETHYL)-1,4,7,10-TETRAAZACYCLODODECAN-1-YL)ACETIC ACID | Tri-tert-Bu-DOTA | FT-07280...
  4. 2,2',2''-(1,4,7-Triazonane-1,4,7-triyl)triacetic Acid
      Grade & Purity: 
    • ≥98%(HPLC)
    Cas Number: 56491-86-2        Compound CID:  124326
    Formula:  C12H21N3O6        Molecular Weight: 303.32
    IUPAC Name:  2-[4,7-bis(carboxymethyl)-1,4,7-triazonan-1-yl]acetic acid
    SMILES:  C1CN(CCN(CCN1CC(=O)O)CC(=O)O)CC(=O)O
    InChIKey: JHALWMSZGCVVEM-UHFFFAOYSA-N
    InChI:  InChI=1S/C12H21N3O6/c16-10(17)7-13-1-2-14(8-11(18)19)5-6-15(4-3-13)9-12(20)21/h1-9H2,(H,16,17)(H,18,19)(H,20,21)
    Synonyms: A902686 | HY-134418 | MFCD00137938 | 1,4,7-Triazacyclononane-N,N',N''-triacetic acid | N,N',N''-Tris(carboxymethyl)-1...
  5. 2,2',2''-(1,4,7-Triazonane-1,4,7-triyl)triacetic Acid
      Grade & Purity: 
    • 10mM in DMSO
    Cas Number: 56491-86-2        Compound CID:  124326
    Formula:  C12H21N3O6        Molecular Weight: 303.32
    IUPAC Name:  2-[4,7-bis(carboxymethyl)-1,4,7-triazonan-1-yl]acetic acid
    SMILES:  C1CN(CCN(CCN1CC(=O)O)CC(=O)O)CC(=O)O
    InChIKey: JHALWMSZGCVVEM-UHFFFAOYSA-N
    InChI:  InChI=1S/C12H21N3O6/c16-10(17)7-13-1-2-14(8-11(18)19)5-6-15(4-3-13)9-12(20)21/h1-9H2,(H,16,17)(H,18,19)(H,20,21)
    Synonyms: NOTA|56491-86-2|2-[4,7-bis(carboxymethyl)-1,4,7-triazonan-1-yl]acetic acid|1,4,7-Triazacyclononane-N,N',N''-triacetic...
  6. Rituximab (anti-CD20), BINDING AGENT of B-lymphocyte antigen CD20 binding agent
      Application: 
    • Flow Cytometry
    Associated targets:  MS4A1
      Short Overview: Immunology & Inflammation related Antibodies    
      Species reactivity(Reacts with): Human    Isotype: Human IgG1    
      Conjugation: Unconjugated    
    Cas Number: 174722-31-7        Compound CID:  168009840
    SMILES:  CC=CC1=CC(=CC=C1)N(CC2=CC=C(C=C2)C3=CC4=C(C=C3)N=CC4)C(=O)C5CCCCC5.CC=CC1=CC(=CC=C1)N(CC2=CC=C(C=C2)C3=CC4=C(C=C3)N=C(O4)C)C(=O)C5CCCCC5.COC(=O)C=CC1=show more
    Synonyms: IDEC-C2B8
  7. Trastuzumab (anti-HER2), Antibody of erb-b2 receptor tyrosine kinase 2
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  ERBB2
      Short Overview: Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated    
      Species reactivity(Reacts with): Human, Mouse    Isotype: Human IgG1    
      Host species: Human    Conjugation: Unconjugated    
    Cas Number: 180288-69-1
    Formula:  C6470H10012N1726O2013S42        Molecular Weight: 145531.50
    IUPAC Name:  2,8-diamino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
    SMILES:  C(C1C(C(C(O1)N2C3=C(C(=O)NC(=N3)N)N=C2N)O)O)O
    InChIKey: FNXPTCITVCRFRK-UMMCILCDSA-N
    InChI:  InChI=1S/C10H14N6O5/c11-9-14-6-3(7(20)15-9)13-10(12)16(6)8-5(19)4(18)2(1-17)21-8/h2,4-5,8,17-19H,1H2,(H2,12,13)(H3,11,14,15,20)/t2-,4-,5-,8-/m1/s1
    Synonyms: 8-Aminoguanosine, >=98% (HPLC) | SHO2CA1BRO | Guanosine, 8-amino- | SCHEMBL483333 | 2,8-diamino-9-[(2R,3R,4S,5R)-3,4-...
  8. Cetuximab (anti-EGFR), Antibody of epidermal growth factor receptor
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  EGFR
      Short Overview: Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level< 0.01EU/μg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated    
      Species reactivity(Reacts with): Cynomolgus monkey, Human, Mouse    Isotype: Human IgG1    
      Host species: Human    Conjugation: Unconjugated    
    Cas Number: 205923-56-4
    Formula:         Molecular Weight: 145543.35
    Synonyms: C225 | Recombinant Cetuximab Antibody | Cetuximab (anti-EGFR) | Cetuximab (C225) | Anti-ERBB1 / EGFR / HER1 Reference...
  9. Lintuzumab (anti-CD33), Antibody of CD33
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  CD33
      Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level < 0.01EU/μg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated    
      Species reactivity(Reacts with): Human    Isotype: Human IgG1    
      Host species: Human    Conjugation: Unconjugated    
    Cas Number: 166089-32-3
    Synonyms: CD 33 antibody | CD33 antibody | CD33 antigen (gp67) antibody | CD33 antigen antibody | CD33 molecule antibody | CD33...
  10. 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester)
      Grade & Purity: 
    • ≥98%
    Cas Number: 173308-19-5        Compound CID:  22660448
    Formula:  C30H58N6O7        Molecular Weight: 614.82
    IUPAC Name:  tert-butyl 2-[4-[2-(2-aminoethylamino)-2-oxoethyl]-7,10-bis[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]-1,4,7,10-tetrazacyclododec-1-yl]acetate
    SMILES:  CC(C)(C)OC(=O)CN1CCN(CCN(CCN(CC1)CC(=O)OC(C)(C)C)CC(=O)OC(C)(C)C)CC(=O)NCCN
    InChIKey: TVUPYCMMXREXSS-UHFFFAOYSA-N
    InChI:  InChI=1S/C30H58N6O7/c1-28(2,3)41-25(38)21-34-14-12-33(20-24(37)32-11-10-31)13-15-35(22-26(39)42-29(4,5)6)17-19-36(18-16-34)23-27(40)43-30(7,8)9/h10-23show more
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