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Recombinant RSK3 Antibody - Primary antibody, specific to RPS6KA2, Rabbit IgG

COA COA
    Application:
  • IF/ICC
  • IHC
  • WB
  • Host species: Rabbit
  • Reactive species: Hamster,Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab126068
Grouped product items
SKU Size
Availability
 Price Qty
Ab126068-10μl
10μl
2
$66.90
Ab126068-50μl
50μl
1
$199.90
Ab126068-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
Ab126068-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,399.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Recombinant; Rabbit anti Human RSK3 Antibody; WB, IHC, ICC, IF; Unconjugated

View related series
Click to view target information: RPS6KA2
Accession#:Q15349 (1) Gene ID:6196 (1) RPS6KA2 (1) RSK3 (1)

Basic Description

Product Name Recombinant RSK3 Antibody - Primary antibody, specific to RPS6KA2, Rabbit IgG
Synonyms 90 kDa ribosomal protein S6 kinase 2 antibody | HU 2 antibody | KS6A2_HUMAN antibody | MAP kinase activated protein kinase 1c antibody | MAP kinase-activated protein kinase 1c antibody | MAPK-activated protein kinase 1c antibody | MAPKAP kinase 1c antibod
Specifications & Purity ExactAb™, Validated, Recombinant, 0.6 mg/mL
Host species Rabbit
Specificity RPS6KA2
Immunogen A synthetic peptide derived from human RSK3 (AA 343-362)
Positive Control WB: C6, NH/3T3, A431, K562 and HEK293 cell lysates. IHC: Human lung cancer tissue. ICC/IF: U87-MG.
Conjugation Unconjugated
Grade ExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human RSK3 Antibody, Recombinant, could be used for WB, IHC, ICC, IF and so on.
Application:
WB: 1/500 - 1/1000
IHC: 1/50-1/100
ICC/IF: 1/50-1/200
Protein Function
Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of transcription factors, regulates translation, and mediates cellular proliferation, survival, and differentiation. May function as tumor suppressor in epithelial ovarian cancer cells.
Post-translational
Activated by phosphorylation at Ser-218 by PDPK1. Autophosphorylated on Ser-377, as part of the activation process. May be phosphorylated at Thr-356 and Ser-360 by MAPK1/ERK2 and MAPK3/ERK1. N-terminal myristoylation results in an activated kinase in the absence of added growth factors.

Product Properties

Isotype Rabbit IgG
SDS-PAGE 150 kDa
Purification Method Antigen affinity purified
Shape Liquid
Concentration 0.6 mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

RPS6KA2 Tchem Ribosomal protein S6 kinase alpha-2 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Recombinant RSK3 Antibody (Ab126068) - Western Blot
All lanes: Recombinant RSK3 Antibody (Ab126068) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/30000 dilution

Predicted band size: 83 kDa
Observed band size: 84 kDa
Exposure time: 11.1 s

Recombinant RSK3 Antibody (Ab126068) - IHC
Immunohistochemistry analysis of paraffin-embedded Human lung cancer tissue using Recombinant RSK3 Antibody (Ab126068). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Recombinant RSK3 Antibody (Ab126068) - IF/ICC
Immunocytochemistry analysis of RSK3 (green) in U87-MG using Recombinant RSK3 Antibody (Ab126068), and cells were counterstained with DAPI (blue).


Application

Application Dilution info
WB

1/500-1/1000
IF/ICC

1/50-1/200

IHC

1/50 - 1/100

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ24F0102516 Certificate of Analysis Jan 18, 2024 Ab126068
ZJ24F0102517 Certificate of Analysis Jan 18, 2024 Ab126068

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