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Recombinant LINE-1 ORF1p Antibody - Primary antibody, specific to L1RE1, Rabbit IgG

COA COA
    Application:
  • WB
  • Host species: Rabbit
  • Reactive species: Human
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab113189
Grouped product items
SKU Size
Availability
 Price Qty
Ab113189-10μl
10μl
2
$69.90
Ab113189-50μl
50μl
1
$199.90
Ab113189-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
Ab113189-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,399.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Recombinant; Rabbit anti Human LINE-1 ORF1p Antibody; WB; Unconjugated

View related series
Click to view target information: L1RE1
Accession#: Q9UN81 (1) Gene ID: 105370531 (1) L1RE1 (1) LINE-1 ORF1p (1)

Basic Description

Product Name Recombinant LINE-1 ORF1p Antibody - Primary antibody, specific to L1RE1, Rabbit IgG
Synonyms L1ORF1p antibody | L1RE1 antibody | LINE retrotransposable element 1 antibody | LINE-1 retrotransposable element ORF1 protein antibody | LINE1 retrotransposable element 1 antibody | LRE1 antibody | L1RE1 | L1ORF1p | LRE1 | LINE-1 ORF1p antibody | Anti-LIN
Specifications & Purity ExactAb™, Validated, Recombinant, 0.6 mg/mL
Host species Rabbit
Specificity L1RE1
Immunogen Recombinant protein of human LINE-1 ORF1p (AA 157-330)
Positive Control WB: HeLa, A431, U-2 OS and A549 cell lysates.
Conjugation Unconjugated
Grade ExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human LINE-1 ORF1p Antibody, Recombinant, could be used for WB and so on.
Application:
WB: 1/500 - 1/1000
Relevance
Domain: The coiled coil domain mediates homotrimerization. The RRM and the CTD domain are both required for proper RNA-binding activity. Function: Nucleic acid-binding protein which is essential for retrotransposition of LINE-1 elements in the genome. Functions as a nucleic acid chaperone binding its own transcript and therefore preferentially mobilizing the transcript from which they are encoded. Long interspersed element-1/LINE-1/L1 retrotransposons are present in more than 500'000 full (6 kb) or truncated copies in the human genome. Most of them are inactive but 80 to 100 of those elements could be transcribed, translated and active in any individual. An active LINE-1 encodes for 2 proteins translated from a single RNA containing 2 non-overlapping ORFs, ORF1 and ORF2. ORF1p is described in this entry as a representative of all ORF1p potentially expressed by active elements. ORF2p is described in the related entry AC O00370. PTM: Polyubiquitinated, probably by UBR2, which induces its degradation. Similarity: Belongs to the transposase 22 family.

Product Properties

Isotype Rabbit IgG
SDS-PAGE 150 kDa
Purification Method Antigen affinity purified
Shape Liquid
Concentration 0.6 mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

L1RE1 Tbio LINE-1 retrotransposable element ORF1 protein (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Images

Recombinant LINE-1 ORF1p Antibody (Ab113189) - Western Blot
All lanes: Recombinant LINE-1 ORF1p Antibody (Ab113189) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 40 kDa
Observed band size: 39 kDa
Exposure time: 56.9 s 

Recombinant LINE-1 ORF1p Antibody (Ab113189) - Western Blot
All lanes: Recombinant LINE-1 ORF1p Antibody (Ab113189) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 40 kDa
Observed band size: 40 kDa
Exposure time: 10.0 s

Application

Application Dilution info
WB

1/500-1/1000

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ24F0607060 Certificate of Analysis Jun 19, 2024 Ab113189
ZJ24F0607059 Certificate of Analysis Jun 19, 2024 Ab113189

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