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Recombinant Emerin Antibody - Primary antibody, specific to EMD, Rabbit IgG

COA COA
    Application:
  • IF/ICC
  • IHC
  • WB
  • Host species: Rabbit
  • Reactive species: Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab101562
Grouped product items
SKU Size
Availability
 Price Qty
Ab101562-10μl
10μl
2
$79.90
Ab101562-50μl
50μl
1
$229.90
Ab101562-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$329.90
Ab101562-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,999.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Recombinant; Rabbit anti Human Emerin Antibody; WB, IHC, IF, ICC; Unconjugated

View related series
Click to view target information: EMD
Accession#:P50402 (1) EMD (1) Emerin (1) Gene ID:2010 (1)

Basic Description

Product Name Recombinant Emerin Antibody - Primary antibody, specific to EMD, Rabbit IgG
Synonyms EDMD | Emd | EMD_HUMAN | Emerin | Emery Dreifuss muscular dystrophy | STA | EDMD antibody | Emd antibody | EMD_HUMAN antibody | Emerin antibody | Emery Dreifuss muscular dystrophy antibody | STA antibody | EDMD | Emd | EMD_HUMAN | Emerin | Emery Dreifuss
Specifications & Purity ExactAb™, Validated, Recombinant, 0.5 mg/mL
Host species Rabbit
Specificity EMD
Immunogen A synthetic peptide derived from human Emerin (AA 200-214)
Positive Control WB: HeLa, NIH/3T3 and C6 cell lysates. IHC: Human breast cancer tissue. ICC/IF: HeLa cells.
Conjugation Unconjugated
Grade ExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human Emerin Antibody, Recombinant, could be used for WB, IHC, IF, ICC and so on.
Application:
WB: 1/500-1/1000
IHC: 1/50-1/100
ICC/IF: 1/50-1/200
Protein Function
Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD. Required for proper localization of non-farnesylated prelamin-A/C.

Product Properties

Isotype Rabbit IgG
SDS-PAGE 150 kDa
Purification Method Antigen affinity purified
Shape Liquid
Concentration 0.5 mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

EMD Tbio Emerin (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Images

Recombinant Emerin Antibody (Ab101562) - Western Blot
All lanes: Recombinant Emerin Antibody (Ab101562) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/30000 dilution

Predicted band size: 29 kDa
Observed band size: 31, 33 kDa
Exposure time: 54.5 s


Recombinant Emerin Antibody (Ab101562) - IF/ICC
Immunocytochemistry analysis of Emerin (green) in HeLa using Recombinant Emerin Antibody (Ab101562), and cells were counterstained with DAPI (blue).

Recombinant Emerin Antibody (Ab101562) - IHC
Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Recombinant Emerin Antibody (Ab101562). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Application

Application Dilution info
WB

1/500-1/1000
IF/ICC

1/50-1/200

IHC

1/50 - 1/100

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ24F0303340 Certificate of Analysis Mar 18, 2024 Ab101562
ZJ24F0303341 Certificate of Analysis Mar 18, 2024 Ab101562

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