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Recombinant DOK1 Antibody - Primary antibody, specific to DOK1, Rabbit IgG

    Application:
  • WB
  • Host species: Rabbit
  • Reactive species: Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab100293
Grouped product items
SKU Size
Availability
Price Qty
Ab100293-10μl
10μl
1
$69.90
Ab100293-50μl
50μl
1
$199.90
Ab100293-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
Ab100293-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,399.90

Recombinant; Rabbit anti Human DOK1 Antibody; WB; Unconjugated

Basic Description

Product Name Recombinant DOK1 Antibody - Primary antibody, specific to DOK1, Rabbit IgG
Synonyms Docking protein 1 62kD antibody | Docking protein 1 antibody | DOK 1 antibody | DOK1 antibody | DOK1_HUMAN antibody | Downstream of tyrosine kinase 1 antibody | p62(dok) antibody | P62DOK antibody | pp62 antibody | DOK1 | pp62 | P62DOK | Anti-DOK1 antibod
Specifications & Purity ExactAb™, Validated, Recombinant, 0.5 mg/mL
Host species Rabbit
Specificity DOK1
Immunogen A synthetic peptide derived from human DOK1 (AA 430-481)
Positive Control WB: K562, Jurkat, NIH/3T3 and C6 cell lysates.
Conjugation Unconjugated
Grade ExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human DOK1 Antibody, Recombinant, could be used for WB and so on.

Application:

WB: 1/500 - 1/1000

Protein Function

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3. 

Post-translational

Constitutively tyrosine-phosphorylated.
Phosphorylated on tyrosine residues by the insulin receptor kinase. Results in the negative regulation of the insulin signaling pathway.

Product Properties

Isotype Rabbit IgG
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein A purified
Shape Liquid
Concentration 0.5 mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

DOK1 Tbio Docking protein 1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Images

Recombinant DOK1 Antibody (Ab100293) - Western Blot
All lanes: Recombinant DOK1 Antibody (Ab100293) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 52 kDa
Observed band size: 44, 58 kDa
Exposure time: 21.5 s 

Recombinant DOK1 Antibody (Ab100293) - Western Blot
All lanes: Recombinant DOK1 Antibody (Ab100293) at 1/1000 dilution
Samples: Lysates at 10 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 52 kDa
Observed band size: 44, 58 kDa
Exposure time: 3.0 s 

Application

Application Dilution info
WB

1/500-1/1000

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ24F0809176 Certificate of Analysis Aug 05, 2024 Ab100293
ZJ24F0809175 Certificate of Analysis Aug 05, 2024 Ab100293

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