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Estrogen Receptor beta Antibody - Primary antibody, specific to Estrogen Receptor beta, Rabbit IgG

COA COA
    Application:
  • IHC
  • WB
  • Host species: Rabbit
  • Reactive species: Human
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab102374
Grouped product items
SKU Size
Availability
 Price Qty
Ab102374-10μl
10μl
2
$69.90
Ab102374-50μl
50μl
1
$209.90
Ab102374-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$339.90
Ab102374-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,399.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

pAb; Rabbit anti Human Estrogen Receptor beta Antibody; WB, IHC; Unconjugated

View related series
Click to view target information: ESR2
Accession#:Q92731 (2) ESR2 (2) Estrogen Receptor beta (2) Gene ID:2100 (2)

Basic Description

Product Name Estrogen Receptor beta Antibody - Primary antibody, specific to Estrogen Receptor beta, Rabbit IgG
Synonyms ER BETA antibody | ER-beta antibody | Erb antibody | ESR B antibody | ESR BETA antibody | ESR2 antibody | ESR2_HUMAN antibody | ESRB antibody | ESTRB antibody | estrogen nuclear receptor beta variant a antibody | estrogen nuclear receptor beta variant b a
Specifications & Purity ExactAb™, Validated, 0.6 mg/mL
Host species Rabbit
Specificity Estrogen Receptor beta
Immunogen A synthetic peptide derived from human Estrogen Receptor beta (AA 480-530)
Positive Control WB: MCF7, HeLa, Jurkat and K562 cell lysates. IHC: Human cervix cancer.
Conjugation Unconjugated
Grade ExactAb™, Validated
Product Description

Rabbit anti Human Estrogen Receptor beta Antibody, Polyclonal, could be used for WB, IHC and so on.
Application
WB: 1/500-1/1000
IHC: 1/50-1/100
Protein Function
Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.

Product Properties

Isotype Rabbit IgG
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein A purified
Shape Liquid
Concentration 0.6 mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

ESR2 Tclin Estrogen receptor beta (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
ESR2 Tclin Estrogen receptor beta (9272 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Estrogen Receptor beta Antibody (Ab102374) - Western Blot
All lanes: Estrogen Receptor beta Antibody (Ab102374) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 59 kDa
Observed band size: 55 kDa
Exposure time: 10.0 s

Estrogen Receptor beta Antibody (Ab102374) - IHC
Immunohistochemistry analysis of paraffin-embedded Human cervix cancer using Estrogen Receptor beta Antibody (Ab102374). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Application

Application Dilution info
WB

1/500-1/1000
IHC

1/50 - 1/100

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ24F0202836 Certificate of Analysis Feb 23, 2024 Ab102374
ZJ24F0202837 Certificate of Analysis Feb 23, 2024 Ab102374

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