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Dishevelled/Dvl1 Antibody - Primary antibody, specific to DVL1, Rabbit IgG

COA COA
    Application:
  • IHC
  • WB
  • Host species: Rabbit
  • Reactive species: Human,Mouse
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab099911
Grouped product items
SKU Size
Availability
 Price Qty
Ab099911-10μl
10μl
1
$76.90
Ab099911-50μl
50μl
4
$219.90
Ab099911-100μl
100μl
3
$359.90
Ab099911-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,999.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

pAb; Rabbit anti Human Dishevelled/Dvl1 Antibody; WB, IHC; Unconjugated

View related series
Click to view target information: DVL1
Accession#:O14640 (1) Dishevelled (1) DVL1 (1) Gene ID:1855 (1)

Basic Description

Product Name Dishevelled/Dvl1 Antibody - Primary antibody, specific to DVL1, Rabbit IgG
Synonyms dishevelled 1 (homologous to Drosophila dsh) | dishevelled, dsh homolog 1 (Drosophila) | Dishevelled1 | Dishevelled-1 | DSH homolog 1 | Dsh | DVL | DVL1 | DVL1L1 | MGC54245 | segment polarity protein dishevelled homolog DVL-1 | Dishevelled 1 antibody | di
Specifications & Purity Carrier Free, ExactAb™, Azide Free, Validated, High Performance, See COA
Host species Rabbit
Specificity DVL1
Immunogen Recombinant DVL1 expressed in E.coli. (AA 150-285)
Positive Control WB: HeLa and A431 cell lysates. IHC: Human glioma tissue, Mouse colon, cerebrum, liver, kidney tissues.
Conjugation Unconjugated
Grade Azide Free, Carrier Free, ExactAb™, High Performance, Validated
Product Description

Rabbit anti Human Dishevelled/Dvl1 Antibody, Polyclonal, could be used for WB, IHC and so on.
Application:
WB: 0.01-2µg/mL
IHC: 5-20µg/mL
Protein Function
Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ).

Product Properties

Isotype Rabbit IgG
SDS-PAGE 150 kDa
Purification Method Protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

DVL1 Tchem Segment polarity protein dishevelled homolog DVL-1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Dishevelled/Dvl1 Antibody (Ab099911) - Western Blot
All lanes: Dishevelled/Dvl1 Antibody (Ab099911) at 1/2000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/40000 dilution

Predicted band size: 75 kDa
Observed band size: 75 kDa
Exposure time: 100.0 s

Dishevelled/Dvl1 Antibody (Ab099911) - IHC
DAB staining on IHC
Samples: Human Glioma Tissue
Primary Ab: 20 µg/mL Dishevelled/Dvl1 Antibody (Ab099911)
Second Ab: 2 µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.

Dishevelled/Dvl1 Antibody (Ab099911) - IHC
DAB staining on IHC
Sample: Mouse Colon Tissue
Primary Ab: 10 µg/mL Dishevelled/Dvl1 Antibody (Ab099911)
Second Ab: 2 µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.

Dishevelled/Dvl1 Antibody (Ab099911) - IHC
DAB staining on IHC
Sample: Mouse Cerebrum Tissue
Primary Ab: 10 µg/mL Dishevelled/Dvl1 Antibody (Ab099911)
Second Ab: 2 µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.

Dishevelled/Dvl1 Antibody (Ab099911) - IHC
DAB staining on IHC
Sample: Mouse Liver Tissue
Primary Ab: 10 µg/mL Dishevelled/Dvl1 Antibody (Ab099911)
Second Ab: 2 µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.

Dishevelled/Dvl1 Antibody (Ab099911) - IHC
DAB staining on IHC
Sample: Mouse Kidney Tissue
Primary Ab: 10 µg/mL Dishevelled/Dvl1 Antibody (Ab099911)
Second Ab: 2 µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.

Application

Application Dilution info
IHC

5-20 µg/mL
WB

0.01-2 µg/mL

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F1101615 Certificate of Analysis Nov 08, 2023 Ab099911
ZJ23F1101614 Certificate of Analysis Nov 08, 2023 Ab099911

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