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Recombinant Caveolin-2 Antibody - Primary antibody, specific to CAV2, Rabbit IgG

    Application:
  • IF/ICC
  • IHC
  • WB
  • Host species: Rabbit
  • Reactive species: Human
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab093252
Grouped product items
SKU Size
Availability
Price Qty
Ab093252-10μl
10μl
2
$76.90
Ab093252-50μl
50μl
1
$229.90
Ab093252-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$339.90
Ab093252-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,599.90

Recombinant; Rabbit anti Human Caveolin-2 Antibody; WB, IHC, ICC, IF; Unconjugated

Basic Description

Product Name Recombinant Caveolin-2 Antibody - Primary antibody, specific to CAV2, Rabbit IgG
Synonyms CAV antibody | CAV2 antibody | CAV2_HUMAN antibody | Caveolae protein 20 kD antibody | Caveolin 2 antibody | Caveolin 2 isoform a and b antibody | Caveolin-2 antibody | MGC12294 antibody | OTTHUMP00000025032 antibody | OTTHUMP00000195982 antibody | CAV |
Specifications & Purity ExactAb™, Validated, Recombinant, 0.2 mg/mL
Host species Rabbit
Specificity CAV2
Immunogen A synthetic peptide derived from human Caveolin-2 (AA 14-27)
Positive Control WB: HeLa, A549, SK-OV-3, U2OS and HUVEC cell lysates. IHC: Human lung cancer tissue. ICC/IF: A549 cells.
Conjugation Unconjugated
Grade ExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human Caveolin-2 Antibody, Recombinant, could be used for WB, IHC, ICC, IF and so on.
Application:
WB: 1/500 - 1/1000
IHC: 1/50-1/100
ICC/IF: 1/50-1/200
Protein Function
May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression.
Post-translational
Post-translational': "Phosphorylated on serine and tyrosine residues. CAV1 promotes phosphorylation on Ser-23 which then targets the complex to the plasma membrane, lipid rafts and caveolae. Phosphorylation on Ser-36 appears to modulate mitosis in endothelial cells (By similarity). Phosphorylation on both Tyr-19 and Tyr-27 is required for insulin-induced 'Ser-727' phosphorylation of STAT3 and its activation. Phosphorylation on Tyr-19 is required for insulin-induced phosphorylation of MAPK1 and DNA binding of STAT3. Tyrosine phosphorylation is induced by both EGF and insulin.

Product Properties

Isotype Rabbit IgG
SDS-PAGE 150 kDa
Purification Method Antigen affinity purified
Shape Liquid
Concentration 0.2 mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

CAV2 Tbio Caveolin-2 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Images

Recombinant Caveolin-2 Antibody (Ab093252) - Western Blot
All lanes: Recombinant Caveolin-2 Antibody (Ab093252) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 18 kDa
Observed band size: 18, 20 kDa
Exposure time: 23.1 s

Recombinant Caveolin-2 Antibody (Ab093252) - IF/ICC
Immunocytochemistry analysis of Caveolin 2 (green) in A549 using Recombinant Caveolin-2 Antibody (Ab093252), and cells were counterstained with DAPI (blue).

Recombinant Caveolin-2 Antibody (Ab093252) - IHC
Immunohistochemistry analysis of paraffin-embedded Human lung cancer tissue using Recombinant Caveolin-2 Antibody (Ab093252). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Application

Application Dilution info
WB

1/500-1/1000

IF/ICC

1/50-1/200

IHC

1/50 - 1/100

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ24F0505418 Certificate of Analysis May 11, 2024 Ab093252
ZJ24F0505417 Certificate of Analysis May 11, 2024 Ab093252

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