GPCR信号通路 - 药物发现8 - 应用

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Recombinant Human PTH1R/PTHR1 Protein

规格或纯度 :

≥95%(SDS-PAGE)

种属: 人(Human) Accession #: Q03431

表达系统: HEK293 蛋白标签: C-His 内毒素水平: <0.1 EU/μg

生物活性: When Recombinant Human PTH1R/PTHR1 is used at 2 μg/mL, the concentration of biotinylated human PTHrP that produces 50% of the optimal binding response is found to be approximately 0.03‑0.12 μg/mL.

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Recombinant Human Frizzled-4 Protein

规格或纯度 :

≥95%(SDS-PAGE)

种属: 人(Human) Accession #: Q9ULV1

表达系统: HEK293 蛋白标签: C-hFc & His 内毒素水平: <0.1 EU/μg

生物活性: Measured by its binding ability in a functional ELISA. In a 100 µL reaction mixture containing biotinylated rmWnt-5a at 100 ng/mL and rhFrizzled-4/Fc Chimera dilutions at 0.1-2,000 ng/mL, the concentration of rhFrizzled-4/Fc Chimera that produces 50% of the optimal binding response is found to be approximately 15-60 ng/mL.

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Recombinant Human Legumain/Asparaginyl Endopeptidase Protein

规格或纯度 :

无动物源

无载体

≥95%(SDS-PAGE)

种属: 人(Human) Accession #: Q99538

表达系统: HEK293 蛋白标签: C-His 内毒素水平: <1.0 EU/μg

生物活性: Testing in progress

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Recombinant Human Frizzled-1 Protein

规格或纯度 :

≥95%(SDS-PAGE)

种属: 人(Human) Accession #: Q9UP38

表达系统: HEK293 蛋白标签: C-hFc & His 内毒素水平: <0.1 EU/μg

生物活性: Measured by its binding ability in a functional ELISA. In a 100 µL reaction mixture containing biotinylated rmWnt-5a at 100 ng/mL and rhFrizzled-1/Fc Chimera dilutions at 0.1-8,000 ng/mL, the concentration of rhFrizzled-1/Fc Chimera that produces 50% of the optimal binding response is found to be approximately 20-80 ng/mL. Optimal concentrations should be determined by each laboratory for each application.

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Recombinant Human Frizzled-9 Protein

规格或纯度 :

≥90%(SDS-PAGE)

种属: 人(Human) Accession #: O00144

表达系统: HEK293 蛋白标签: C-hFc & His 内毒素水平: <0.1 EU/μg

生物活性: Measured by its ability to bind biotinylated recombinant mouse Wnt-3a in a functional ELISA with an ED50 of 15-90 ng/mL.

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Recombinant Mouse Frizzled-2 Protein

规格或纯度 :

≥95%(SDS-PAGE)

种属: 小鼠(Mouse) Accession #: Q9JIP6

表达系统: HEK293 蛋白标签: C-hFc & His 内毒素水平: <0.1 EU/μg

生物活性: Measured by its ability to bind biotinylated Wnt-5a in a functional ELISA with an estimated Kd <5 nM.

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Recombinant Human GIPR Protein

规格或纯度 :

无动物源

无载体

≥95%(SDS-PAGE)
见COA

种属: 人(Human) Accession #: P48546

表达系统: HEK293 蛋白标签: C-His 内毒素水平: <1.0 EU/μg

生物活性: Testing in progress

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Recombinant Human GPR37 Protein

规格或纯度 :

≥95%(SDS-PAGE)
见COA

种属: 人(Human) Accession #: O15354

表达系统: HEK293 蛋白标签: C-10His 内毒素水平: <1.0 EU/μg

生物活性: Immobilized Recombinant Human GPR37 Protein (rp192118) at 1.0 μg/mL can bind Recombinant GPCR/GPR37 Antibody (Ab106130) with the EC50 of 2.9 ng/mL.

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