Recombinant Human Frizzled-9 Protein

COA

级别和纯度:

≥90%(SDS-PAGE)

表达系统: HEK293
Accession #: O00144
蛋白标签: C-hFc & His
生物活性: Measured by its ability to bind biotinylated recombinant mouse Wnt-3a in a functional ELISA with an ED50 of 15-90 ng/mL.
内毒素水平: <0.1 EU/μg

有货

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货号 (SKU)	包装规格	是否现货
rp165192-10μg	10μg	现货
rp165192-50μg	50μg	现货
rp165192-100μg	100μg	现货
rp165192-1mg	1mg	期货

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点击查看蛋白信息: FZD9

Accession#:O00144 (1) CD349 (1) Frizzled9 (1) FZD9 (1) Gene ID:8326 (1)

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基本描述

产品名称	Recombinant Human Frizzled-9 Protein
别名	卷曲同源物9(FZD9)重组蛋白
英文别名	CD349 antigen \| CD349 \| frizzled (Drosophila) homolog 9 \| frizzled homolog 9 (Drosophila) \| Frizzled9 \| Frizzled-9 \| fz-9 \| FZD3 \| fzE6 \| FZD9 \| hFz9
规格或纯度	ActiBioPure™, 生物活性, 无动物源, Carrier Free, ≥90%(SDS-PAGE)
产品介绍	Function Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
生物活性	Measured by its ability to bind biotinylated recombinant mouse Wnt-3a in a functional ELISA with an ED50 of 15-90 ng/mL.
内毒素水平	<0.1 EU/μg
表达系统	HEK293
种属	人(Human)
氨基酸	23-185 aa
序列	LEIGRFDPERGRGAAPCQAVEIPMCRGIGYNLTRMPNLLGHTSQGEAAAELAEFAPLVQYGCHSHLRFFLCSLYAPMCTDQVSTPIPACRPMCEQARLRCAPIMEQFNFGWPDSLDCARLPTRNDPHALCMEAPENATAGPAEPHKGLGMLPVAPRPARPPGDENLYFQGMDPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH
蛋白标签	C-hFc & His
无载体	Yes
无动物源	Yes
Accession #	O00144
来源	重组表达
预测分子量	45.5 kDa
SDS-PAGE	56 kDa, under reducing conditions; 116 kDa, under non-reducing conditions.

储存与运输

物理形态	冻干(Lyophilized)
储存缓冲液	Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH 7.4
复溶	Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	在 -20~-80℃ 下可保存 1 年以上。收货后建议分装。避免冷冻/解冻循环。
分子类型	蛋白质

图片

SDS-PAGE: Recombinant Human Frizzled-9 Protein (rp165192)

Recombinant Human Frizzled-9 Protein (rp165192) - SDS-PAGE
2 μg/lane of Recombinant Human Frizzled-9 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 56 kDa under reducing condition and 116 kDa under non-reducing condition.

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找到3个结果

批号(Lot Number)	证书类型	货号
ZJ25F0420663	分析证书	rp165192
ZJ25F0420662	分析证书	rp165192
ZJ25F0420661	分析证书	rp165192

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