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Recombinant Retinoic Acid Receptor alpha Antibody - Primary antibody, specific to RARA, Rabbit IgG

COA COA
    Application:
  • WB
  • Host species: Rabbit
  • Reactive species: Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab125108
Grouped product items
SKU Size
Availability
 Price Qty
Ab125108-10μl
10μl
2
$66.90
Ab125108-50μl
50μl
1
$189.90
Ab125108-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
Ab125108-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,599.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Recombinant; Rabbit anti Human Retinoic Acid Receptor alpha Antibody; WB; Unconjugated

View related series
Click to view target information: RARA
Accession#:P10276 (1) Gene ID:5914 (1) RARA (1) Retinoic Acid Receptor alpha (1)

Basic Description

Product Name Recombinant Retinoic Acid Receptor alpha Antibody - Primary antibody, specific to RARA, Rabbit IgG
Synonyms alpha polypeptide | NR1B1 | RAR alpha | RARA | RAR-alpha | retinoic acid receptor, alpha | RAR | RARalpha | NR1B1 antibody | Nuclear mitotic apparatus protein retinoic acid receptor alpha fusion protein antibody | Nuclear receptor subfamily 1 group B memb
Specifications & Purity ExactAb™, Validated, Recombinant, 1.0 mg/mL
Host species Rabbit
Specificity RARA
Immunogen A synthetic peptide derived from human Retinoic Acid Receptor alpha (AA 5-30)
Positive Control WB: Mouse brain, MCF7, Hep G2, HEK293 and C6 lysates.
Conjugation Unconjugated
Grade ExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human Retinoic Acid Receptor alpha Antibody, Recombinant, could beused for WB and so on.
Application:
WB: 1/500-1/1000
Protein Function:
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression. On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation. RARA plays an essential role in the regulation of retinoic acid-induced germ cell development during spermatogenesis. Has a role in the survival of early spermatocytes at the beginning prophase of meiosis. In Sertoli cells, may promote the survival and development of early meiotic prophase spermatocytes. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function (By similarity). Regulates expression of target genes in a ligand-dependent manner by recruiting chromatin complexes containing MLL5. Mediates retinoic acid-induced granulopoiesis.

Product Properties

Isotype Rabbit IgG
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein A purified
Shape Liquid
Concentration 1.0 mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

RARA Tclin Retinoic acid receptor alpha (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
RARA Tclin Retinoic acid receptor alpha (1324 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Recombinant Retinoic Acid Receptor alpha Antibody (Ab125108) - Western Blot
All lanes: Recombinant Retinoic Acid Receptor alpha Antibody (Ab125108) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 51 kDa
Observed band size: 59 kDa
Exposure time: 100.0 s

Recombinant Retinoic Acid Receptor alpha Antibody (Ab125108) - Western Blot
All lanes: Recombinant Retinoic Acid Receptor alpha Antibody (Ab125108) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 51 kDa
Observed band size: 59 kDa
Exposure time: 60.0 s

Application

Application Dilution info
WB

1/500-1/1000

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ24F0505731 Certificate of Analysis May 16, 2024 Ab125108
ZJ24F0505730 Certificate of Analysis May 16, 2024 Ab125108

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