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Recombinant PIM2 Antibody - Primary antibody, specific to PIM2, Rabbit IgG

    Application:
  • WB
  • Host species: Rabbit
  • Reactive species: Human
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab121878
Grouped product items
SKU Size
Availability
Price Qty
Ab121878-10μl
10μl
2
$69.90
Ab121878-50μl
50μl
1
$209.90
Ab121878-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$309.90
Ab121878-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,399.90

Recombinant; Rabbit anti Human PIM2 Antibody; WB; Unconjugated

Basic Description

Product Name Recombinant PIM2 Antibody - Primary antibody, specific to PIM2, Rabbit IgG
Synonyms OTTHUMP00000025825 antibody | Pim 2 oncogene antibody | Pim 2h antibody | Pim-2h antibody | PIM2 antibody | PIM2 Oncogene antibody | PIM2_HUMAN antibody | Pim2h antibody | Proto Oncogene PIM2 antibody | Proto-oncogene Pim-2 (serine threonine kinase) antib
Specifications & Purity ExactAb™, Validated, Recombinant, 1.3 mg/mL
Host species Rabbit
Specificity PIM2
Immunogen A synthetic peptide derived from human PIM2 (AA 266-280)
Positive Control WB: Raji, K562 and Jurkat cell lysates.
Conjugation Unconjugated
Grade ExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human PIM2 Antibody, Recombinant, could be used for WB and so on.
Application:
WB: 1/500 - 1/1000
Protein Function
Promotes cell survival in response to a variety of proliferative signals via positive regulation of the I-kappaB kinase/NF-kappaB cascade; this process requires phosphorylation of MAP3K8/COT. Prevents apoptosis induced by growth factor withdrawal via inhibition of caspase-3 activation, and via phosphorylation of pro-apoptotic proteins. Inhibits BAD-induced cell death via phosphorylation of BAD. PIM2-mediated cell survival is glucose-dependent but independent of several AKT regulators such as PI3K, HSP-90 and TOR, indicating that PIM2 and PI3K/AKT/TOR function via distinct pathways. Involved in the positive regulation of chondrocyte survival and autophagy in the epiphyseal growth plate.
Post-translational
Autophosphorylated.

Product Properties

Isotype Rabbit IgG
SDS-PAGE 150 kDa
Purification Method Antigen affinity purified
Shape Liquid
Concentration 1.3 mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

PIM2 Tchem Serine/threonine-protein kinase pim-2 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Recombinant PIM2 Antibody (Ab121878) - Western Blot
All lanes: Recombinant PIM2 Antibody (Ab121878) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 34 kDa
Observed band size: 36 kDa
Exposure time: 3.2 s


Application

Application Dilution info
WB

1/500-1/1000

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ24F0607541 Certificate of Analysis Jun 28, 2024 Ab121878
ZJ24F0607540 Certificate of Analysis Jun 28, 2024 Ab121878

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