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Recombinant LSD2/AOF1 Antibody - Primary antibody, specific to KDM1B, Rabbit IgG

COA COA
    Application:
  • WB
  • Host species: Rabbit
  • Reactive species: Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab113646
Grouped product items
SKU Size
Availability
 Price Qty
Ab113646-10μl
10μl
2
$69.90
Ab113646-50μl
50μl
1
$209.90
Ab113646-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$309.90
Ab113646-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,799.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Recombinant; Rabbit anti Human LSD2/AOF1 Antibody; WB; Unconjugated

View related series
Click to view target information: MED19 Click to view target information: KDM1B
Accession#: Q8NB78 (1) AOF1 (1) Gene ID: 221656 (1) KDM1B (1) LSD2 (1)

Basic Description

Product Name Recombinant LSD2/AOF1 Antibody - Primary antibody, specific to KDM1B, Rabbit IgG
Synonyms EC 1.14.99.66 | Flavin-containing amine oxidase domain-containing protein 1 | Lysine-specific histone demethylase 2 | amine oxidase (flavin containing) domain 1antibody | amine oxidase, flavin containing 1 antibody | AOF1 antibody | bA204B7.3 antibody | C
Specifications & Purity ExactAb™, Validated, Recombinant, 0.6 mg/mL
Host species Rabbit
Specificity KDM1B
Immunogen A synthetic peptide derived from human LSD2/AOF1 (AA 75-136)
Positive Control WB: HeLa, Hep G2 and A549 cell lysates.
Conjugation Unconjugated
Grade ExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human LSD2/AOF1 Antibody, Recombinant, could be used for WB and so on.

Application:

WB: 1/500-1/1000

Function

Histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri-methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys-36' of histone H3, or on mono-, di- or tri-methylated 'Lys-20' of histone H4. 

Product Properties

Isotype Rabbit IgG
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein A purified
Shape Liquid
Concentration 0.6 mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

MED19 Tbio Mediator of RNA polymerase II transcription subunit 19 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
KDM1B Tbio Lysine-specific histone demethylase 1B (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Recombinant LSD2/AOF1 Antibody (Ab113646) - Western Blot
All lanes: Recombinant LSD2/AOF1 Antibody (Ab113646) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 92 kDa
Observed band size: 92 kDa
Exposure time: 60.0 s

Application

Application Dilution info
WB

1/500-1/1000

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ24F0708739 Certificate of Analysis Jul 25, 2024 Ab113646
ZJ24F0708738 Certificate of Analysis Jul 25, 2024 Ab113646

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