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Recombinant DYNLL1/PIN Antibody - Primary antibody, specific to DYNLL1, Rabbit IgG

COA COA
    Application:
  • IHC
  • WB
  • Host species: Rabbit
  • Reactive species: Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab100668
Grouped product items
SKU Size
Availability
 Price Qty
Ab100668-10μl
10μl
2
$66.90
Ab100668-50μl
50μl
1
$199.90
Ab100668-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
Ab100668-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,699.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Recombinant; Rabbit anti Human DYNLL1/PIN Antibody; WB, IHC; Unconjugated

View related series
Click to view target information: DYNLL1
Accession#:P63167 (2) DYNLL1 (2) Gene ID:8655 (2) PIN (1)

Basic Description

Product Name Recombinant DYNLL1/PIN Antibody - Primary antibody, specific to DYNLL1, Rabbit IgG
Synonyms cytoplasmic dynein light polypeptide | DLC1 | DLC1DNCLC1 | DLC8 | DLC8MGC126137 | DNCL1 | DNCL1MGC126138 | DNCLC1 | dynein light chain 1, cytoplasmic | Dynein light chain LC8-type 1 | dynein, cytoplasmic, light polypeptide 1 | dynein, light chain, LC8-typ
Specifications & Purity ExactAb™, Validated, Recombinant, 1.0 mg/mL
Host species Rabbit
Specificity DYNLL1
Immunogen A synthetic peptide derived from human DYNLL1 (AA 2-14)
Positive Control WB: HeLa, Hep G2, MCF7, NIH/3T3 and C6 cell lysates. IHC: Human colon cancer tissue.
Conjugation Unconjugated
Grade ExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human DYNLL1/PIN Antibody, Recombinant, could be used for WB, IHC and so on.
Application:
WB: 1/500-1/1000
IHC: 1/50-1/100
Protein Function
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
Binds and inhibits the catalytic activity of neuronal nitric oxide synthase.
Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1.
Regulates apoptotic activities of BCL2L11 by sequestering it to microtubules. Upon apoptotic stimuli the BCL2L11-DYNLL1 complex dissociates from cytoplasmic dynein and translocates to mitochondria and sequesters BCL2 thus neutralizing its antiapoptotic activity.

Product Properties

Isotype Rabbit IgG
SDS-PAGE 150 kDa
Purification Method Immunogen affinity purified
Shape Liquid
Concentration 1.0 mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

DYNLL1 Tbio Dynein light chain 1, cytoplasmic (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Images

Recombinant DYNLL1/PIN Antibody (Ab100668) - Western Blot
All lanes: Recombinant DYNLL1/PIN Antibody (Ab100668) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 10 kDa
Observed band size: 12 kDa
Exposure time: 30.0 s

Recombinant DYNLL1/PIN Antibody (Ab100668) - IHC
Immunohistochemistry analysis of paraffin-embedded Human colon cancer using Recombinant DYNLL1/PIN Antibody (Ab100668). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Application

Application Dilution info
WB

1/500-1/1000
IHC

1/50 - 1/100

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ24F0303274 Certificate of Analysis Mar 14, 2024 Ab100668
ZJ24F0303273 Certificate of Analysis Mar 14, 2024 Ab100668

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