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Recombinant Aprataxin Antibody - Primary antibody, specific to APTX, Rabbit IgG

    Application:
  • IF/ICC
  • WB
  • Host species: Rabbit
  • Reactive species: Human
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab089394
Grouped product items
SKU Size
Availability
Price Qty
Ab089394-10μl
10μl
2
$69.90
Ab089394-50μl
50μl
1
$199.90
Ab089394-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$309.90
Ab089394-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,699.90

Recombinant; Rabbit anti Human Aprataxin Antibody; WB, ICC, IF; Unconjugated

Basic Description

Product Name Recombinant Aprataxin Antibody - Primary antibody, specific to APTX, Rabbit IgG
Synonyms EC 3.6.1.71 | EC 3.6.1.72 | FHA-HIT | Forkhead-associated domain histidine triad-like protein | AOA 1 antibody | AOA antibody | AOA1 antibody | Aprataxin antibody | Aprataxin homolog antibody | Aptx antibody | APTX_HUMAN antibody | Ataxia 1 early onset wi
Specifications & Purity ExactAb™, Validated, Recombinant, 1.0 mg/mL
Host species Rabbit
Specificity APTX
Immunogen A synthetic peptide derived from human Aprataxin (AA 147-160)
Positive Control WB: K562, HeLa, Hep G2 and A549 cell lysates. ICC/IF: U87-MG cells.
Conjugation Unconjugated
Grade ExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human Aprataxin Antibody, Recombinant, could be used for WB, ICC, IF and so on.
Application:
WB: 1/500-1/1000
ICC/IF: 1/50-1/200
Protein Function
DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined. Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP-NH(2)) and diadenosine tetraphosphate (AppppA), but with lower catalytic activity.

Product Properties

Isotype Rabbit IgG
SDS-PAGE 150 kDa
Purification Method Antigen affinity purified
Shape Liquid
Concentration 1.0 mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

APTX Tbio Aprataxin (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Recombinant Aprataxin Antibody (Ab089394) - Western Blot
All lanes: Recombinant Aprataxin Antibody (Ab089394) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 41 kDa
Observed band size: 42 kDa
Exposure time: 24.8 s

Recombinant Aprataxin Antibody (Ab089394) - IF/ICC
Immunocytochemistry analysis of Aprataxin (green) in U87-MG using Recombinant Aprataxin Antibody (Ab089394), and cells were counterstained with DAPI (blue).

Application

Application Dilution info
WB

1/500-1/1000

IF/ICC

1/50-1/200

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ24F0505874 Certificate of Analysis May 21, 2024 Ab089394
ZJ24F0505875 Certificate of Analysis May 21, 2024 Ab089394

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