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Fas Antibody - Primary antibody, specific to Fas, Rabbit IgG

    Application:
  • IHC
  • WB
  • Host species: Rabbit
  • Reactive species: Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab102968
Grouped product items
SKU Size
Availability
Price Qty
Ab102968-10μl
10μl
10
$69.90
Ab102968-50μl
50μl
4
$209.90
Ab102968-100μl
100μl
2
$309.90
Ab102968-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,199.90

pAb; Rabbit anti Human Fas Antibody; WB, IHC; Unconjugated

Basic Description

Product Name Fas Antibody - Primary antibody, specific to Fas, Rabbit IgG
Synonyms ALPS 1A antibody | ALPS1A antibody | APO 1 antibody | Apo 1 antigen antibody | APO 1 cell surface antigen antibody | Apo-1 antigen antibody | APO1 antibody | Apo1 antigen antibody | APO1 cell surface antigen antibody | Apoptosis antigen 1 antibody | Apopt
Specifications & Purity Carrier Free, ExactAb™, Validated, High Performance, See COA
Host species Rabbit
Specificity Fas
Immunogen Recombinant Fas expressed in E.coli (AA 22-172).
Positive Control WB: HeLa, Jurkat, NIH/3T3 and C6 cell lysates. IHC: Human endometrial cancer, tonsil and prostate tissues.
Conjugation Unconjugated
Grade Carrier Free, ExactAb™, High Performance, Validated
Product Description

Rabbit anti Human Fas Antibody, Polyclonal, could be used for WB, IHC and so on.
Application
WB: 0.01-2 μg/mL
IHC: 5-20 μg/mL
Protein Function
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).

Product Properties

Isotype Rabbit IgG
SDS-PAGE 150 kDa
Purification Method Antigen affinity purified and Protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

FAS Tbio Tumor necrosis factor receptor superfamily member 6 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Fas Antibody (Ab102968) - Western Blot
All lanes: Fas Antibody (Ab102968) at 1/2000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/10000 dilution

Predicted band size: 38 kDa
Observed band size: 40-45 kDa
Exposure time: 35.0 s

Fas Antibody (Ab102968) - IHC
DAB staining on IHC
Sample: Human Endometrial cancer Tissue
Primary Ab: 10 µg/mL Fas Antibody (Ab102968)
Second Ab: 2 µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.

Fas Antibody (Ab102968) - IHC
DAB staining on IHC
Sample: Human Tonsil Tissue
Primary Ab: 10 µg/mL Fas Antibody (Ab102968)
Second Ab: 2 µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.

Fas Antibody (Ab102968) - IHC
DAB staining on IHC
Sample: Human Prostate Tissue
Primary Ab: 10 µg/mL Fas Antibody (Ab102968)
Second Ab: 2 µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.

Fas Antibody (Ab102968) - IHC
DAB staining on IHC
Sample: Human Prostate Tissue
Primary Ab: 10 µg/mL Fas Antibody (Ab102968)
Control: Used PBS instead of primary antibody
Second Ab: 2 µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.

Fas Antibody (Ab102968) - IHC
DAB staining on IHC
Sample: Human Tonsil Tissue
Primary Ab: 10 µg/mL Fas Antibody (Ab102968)
Control: Used PBS instead of primary antibody
Second Ab: 2 µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.

Application

Application Dilution info
IHC

5-20 µg/mL

WB

0.01-2 µg/mL

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0505217 Certificate of Analysis May 08, 2024 Ab102968
ZJ24F0505216 Certificate of Analysis May 08, 2024 Ab102968
ZJ24F0505215 Certificate of Analysis May 08, 2024 Ab102968

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