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代谢疾病靶点
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Recombinant Mouse Leptin ProteinCAS号: 181030-10-4分子式: NA种属: 小鼠(Mouse) Accession #: Q544U0表达系统: E. coli 蛋白标签: No tag 内毒素水平: <1.0 EU/μg生物活性: Immobilized Recombinant Mouse LEPR (C-10His) at 5μg/ml (100 μl/well) can bind Recombinant Mouse Leptin Biotinylated by NHS-biotin prior to testing.The ED50 of Recombinant Mouse Leptin is 1.16 ng/ml. Loaded Recombinant Mouse LEPR (C-10His) on HIS1K Biosensor, can bind Recombinant Mouse Leptin with an affinity constant of 0.196 nM as determined in BLI assay.
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Recombinant Human TNF-alpha Protein种属: 人(Human) Accession #: P01375表达系统: E. coli 蛋白标签: No tag 内毒素水平: <0.1 EU/μg生物活性: Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D (Catalog # A113142). The ED₅₀ for this effect is typically <0.05 ng/mL.
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Recombinant Human IL-2 Protein种属: 人(Human) Accession #: P60568表达系统: CHO-K1 蛋白标签: His 内毒素水平: <1.0 EU/μg生物活性: 1、Measured in a cell proliferation assay using CTLL‑2 mouse cytotoxic T cells. The ED50 for this effect is typically less than 2.5 ng/mL. 2、Measured in a cell proliferation assay using mouse splenocytes. The ED50 for this effect is typically less than 30.0 ng/mL.
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Recombinant Rat TNF-alpha Protein种属: 大鼠(Rat) Accession #: P16599表达系统: HEK293 蛋白标签: C-His 内毒素水平: <0.1 EU/μg生物活性: Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D (Catalog # A113142). The EC50 for this effect is typically <5 pg/mL.
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Recombinant Mouse IL-2 Protein种属: 小鼠(Mouse) Accession #: P04351表达系统: HEK293 蛋白标签: N-His 内毒素水平: <1.0 EU/μg生物活性: Recombinant Mouse IL-2 stimulates cell proliferation of the CTLL-2 mouse cytotoxic T cell line. The ED50 for this effect is typically less than 2.5 ng/mL.
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Recombinant Human IL-10 Protein种属: 人(Human) Accession #: P22301表达系统: E. coli 蛋白标签: No tag 内毒素水平: <1.0 EU/μg生物活性: 1. Measured in a cell proliferation assay using MC/9-2 mouse mast cells. The ED₅₀ for this effect is typically 1.0 - 8.0 ng/mL. 2. Immobilized Recombinant Human IL-10 Protein (rp147355) at 2 μg/mL can bind Recombinant Rhesus IL10RA Protein (Fc Tag) the EC₅₀ for this effect is 100.0 - 300.0 ng/mL.
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Recombinant Human NRG1/HRG1 Protein种属: 人(Human) Accession #: Q02297表达系统: HEK293 蛋白标签: C-His 内毒素水平: <0.1 EU/μg生物活性: Measured in a serum-free cell proliferation assay using MCF‑7 human breast cancer cells. The ED₅₀ for this effect is 20‑100 ng/mL.
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Recombinant Human FGF19 Protein种属: 人(Human) Accession #: O95750表达系统: E. coli 蛋白标签: N-His 内毒素水平: <1.0 EU/μg生物活性: FGF19 is a member of the fibroblast growth factor (FGF) family. FGFs are heparin-binding growth factors with a core 120 amino acid (aa) FGF domain that allows for a common tertiary structure. In general, FGFs are expressed during embryonic development and in restricted adult tissues. Human FGF-19 cDNA predicts a 251 aa precursor protein with a 22 aa signal peptide and a 229 aa secreted mature protein with no potential N-linked glycosylation sites. FGF19-FGFR1 is one of paired transcripts mediating the dialogues between extraembryonic membrane and endometrium. A functional binding ELISA assay was conducted to detect the interaction of Recombinant Human FGF19 Protein (rp145934) and recombinant human FGFR1, the EC50 for this effect is 0.16 μg/mL.
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Recombinant Human IL-1 beta Protein种属: 人(Human) Accession #: P01584表达系统: E. coli 蛋白标签: C-His 内毒素水平: <1.0 EU/μg生物活性: Measured in a cell proliferation assay using D10.G4.1 mouse helper T cells. The ED50 for this effect is 0.217-0.870 ng/mL.
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Recombinant Mouse TRANCE/RANKL/TNFSF11 Protein种属: 小鼠(Mouse) Accession #: O35235表达系统: HEK293 蛋白标签: N-Met & Fc 内毒素水平: <0.01 EU/μg生物活性: Measured by its ability to induce TRAP activity in Raw 264.7 cells.The ED50 of each lot is between 2-10 ng/mL.
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Recombinant Mouse FGF-21 Protein种属: 小鼠(Mouse) Accession #: Q9JJN1表达系统: E. coli 蛋白标签: No tag 内毒素水平: <0.1 EU/μg生物活性: Fully biologically active when compared to standard. The ED₅₀ as determined by thymidine uptake assay using FGF-receptors transfected BaF3 cells is less than 0.5 μg/ml, corresponding to a specific activity of >2.0 ×10³IU/mg in the presence of 5 µg/ml of rMuβ-Klotho and 10 μg/ml of heparin.
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Recombinant Mouse IL-10 Protein种属: 小鼠(Mouse) Accession #: P18893表达系统: HEK293 蛋白标签: C-His 内毒素水平: <0.1 EU/μg生物活性: Measured in a cell proliferation assay using MC/9‑2 mouse mast cells. The ED₅₀ for this effect is 0.8 ng/mL.
