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Recombinant Mouse TRANCE/RANKL/TNFSF11 Protein

  • 表达系统: HEK293
  • Accession #: O35235
  • 蛋白标签: N-Met & Fc
  • 生物活性: Measured by its ability to induce TRAP activity in Raw 264.7 cells.The ED50 of each lot is between 2-10 ng/mL.
  • 内毒素水平: <0.01 EU/μg
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货号 (SKU) 包装规格 是否现货 价格 数量
rp154577-2μg
2μg 现货 Stock Image
rp154577-10μg
10μg 现货 Stock Image
rp154577-50μg
50μg 现货 Stock Image
rp154577-1mg
1mg 期货 Stock Image

基本描述

产品名称 Recombinant Mouse TRANCE/RANKL/TNFSF11 Protein
别名 重组小鼠 TRANCE/RANKL/TNFSF11 蛋白
英文别名 CD254 antigen | CD254 | ODF | OPGL | OPGLOPTB2 | Osteoclast differentiation factor | Osteoprotegerin ligand | RANK L | RANKL | RANKLreceptor activator of nuclear factor kappa B ligand | Receptor activator of nuclear factor kappa-B ligand | sOdf | TNF-rela
规格或纯度 ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥95%(SDS-PAGE)
产品介绍


Purity

>95% SDS-PAGE.


Actual molecular weight

19 kDa


Additional sequence information

Soluble Receptor Activator of NFkB Ligand


Function

Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.


Post-translational

The soluble form of isoform 1 derives from the membrane form by proteolytic processing (By similarity). The cleavage may be catalyzed by ADAM17.

生物活性 Measured by its ability to induce TRAP activity in Raw 264.7 cells.The ED50 of each lot is between 2-10 ng/mL.
内毒素水平 <0.01 EU/μg
表达系统 HEK293
种属 小鼠(Mouse)
氨基酸 72-316 aa
序列 MPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKRAQMDPNRISEDSTHCFYRILRLHENADLQDSTLESEDTLPDSCRRMKQAFQGAVQKELQHIVGPQRFSGAPAMMEGSWLDVAQRGKPEAQPFAHLTINAASIPSGSHKVTLSSWYHDRGWAKISNMTLSNGKLRVNQDGFYYLYANICFRHHETSGSVPTDYLQLMVYVVKTSIKIPSSHNLMKGGSTKNWSGNSEFHFYSINVGGFFKLRAGEEISIQVSNPSLLDPDQDATYFGAFKVQDID
纯度 >95%(SDS-PAGE)
蛋白标签 N-Met & Fc
无载体 Yes
无动物源 Yes
Accession # O35235
来源 重组表达
预测分子量 56kDa

储存与运输

物理形态 冻干(Lyophilized)
储存缓冲液 10mM PBS(PH7.4), containing 5% trehalose, 5% mannitol
复溶 Reconstitute in water to a concentration of 0.1-1.0 mg/ml
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 在 -20~-80℃ 下可保存 1 年以上。
分子类型 蛋白质

图片

Recombinant Mouse TRANCE/RANK L/TNFSF11 Protein (rp154577) - Protein Bioactivity
Measured by its ability to induce TRAP activity in Raw 264.7 cells. The ED₅₀ of this effect is 7.0 ng/mL.

Recombinant Mouse TRANCE/RANK L/TNFSF11 Protein (rp154577) - SDS-PAGE
2.5 μg/lane of Recombinant Mouse TRANCE/RANK L/TNFSF11 was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 57.4 kDa under reducing condition and 114.0 kDa under non-reducing condition.

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找到8个结果

批号(Lot Number) 证书类型 货号
ZJ24F1215089 分析证书 rp154577
ZJ24F1215088 分析证书 rp154577
ZJ24F1215090 分析证书 rp154577
ZJ23F1101629 分析证书 rp154577
ZJ23F1101631 分析证书 rp154577
ZJ23F1101630 分析证书 rp154577
ZJ24F0607411 分析证书 rp154577
ZJ24F0607412 分析证书 rp154577

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