货号 (SKU)

包装规格

是否现货

价格

数量

Ab109766-10μl

10μl

现货

Ab109766-50μl

50μL

现货

Ab109766-100μl

100μL

现货

Ab109766-1ml

1ml

期货

基本信息

产品名称	IL-1 alpha Mouse mAb
别名	白介素1α抗体 \| 白介素1α单克隆抗体 \| IL-1 alpha抗体 \| IL-1 alpha单克隆抗体 \| IL1A抗体 \| IL1A单克隆抗体
英文别名	BAF antibody \| FAF antibody \| Hematopoietin 1 antibody \| Hematopoietin-1 antibody \| IL 1 alpha antibody \| IL 1A antibody \| IL-1 alpha antibody \| Il-1a antibody \| IL1 ALPHA antibody \| IL1 antibody \| IL1A antibody \| IL1A_HUMAN antibody \| IL1F1 antibody \| In
规格或纯度	无载体, ExactAb™, 无叠氮钠, 已验证, 见COA
生化机理	Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
宿主种属	小鼠(Mouse)
特异性	IL1A
种属反应性	人(Human),小鼠(Mouse)
免疫原	Recombinant IL1a expressed in E.coli (AA 113-271).
阳性对照	WB: RAW 264.7 and CTLL-2 cell lysates.
偶联	Unconjugated

产品属性

克隆类型	单克隆抗体
克隆号	3#
Format	Whole IgG
亚型	Mouse IgG2b
轻链亚型	kappa
SDS-PAGE	150 kDa
纯化方法	Protein A + Protein G purified
物理外观	Liquid
储存缓冲液	10mM PBS, 50% Glycerol, 0.05% Proclin 300, pH 7.4
防腐剂	0.05% Proclin 300
浓度	见COA
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	4℃ 短期储存（1-2 周）。-20℃长期保存（24 个月）。收货后建议分装。避免冷冻/解冻循环。
分子类型	抗体

关联靶点（人）

IL1A Tchem 白细胞介素-1α(Interleukin-1 alpha) (0 活性数据)

点击查看靶蛋白信息： IL1A

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

图片

Western Blot: IL-1 alpha Mouse mAb (Ab109766)

IL-1 alpha Mouse mAb (Ab109766) - Western Blot
All lanes: IL-1 alpha Mouse mAb (Ab109766) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab138040) at 1/20000 dilution

Predicted band size: 30 kDa
Observed band size: 32 kDa
Exposure time: 100.0 s

应用

应用名称	稀释比例
WB	0.5-2µg/mL

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找到8个结果

批号(Lot Number)	证书类型	货号
ZJ23F1201900	分析证书	Ab109766
ZJ23F1201901	分析证书	Ab109766
ZJ23F1201902	分析证书	Ab109766
ZJ25F0420189	分析证书	Ab109766
ZJ25F0420188	分析证书	Ab109766
ZJ25F0420187	分析证书	Ab109766
ZJ24F1011855	分析证书	Ab109766
ZJ24F1011777	分析证书	Ab109766

技术文档和文章

酶联免疫斑点技术（ELISPOT）实验方案

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细胞因子生长因子酶联免疫斑点技术分泌蛋白辣根过氧化物酶偶联二抗

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重组抗体单克隆抗体多克隆抗体蛋白质印迹内参抗体一抗选择

Guidelines of Primary Antibodies for Western Blotting

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Western blotting Monoclonal antibodies Recombinant Antibodies Polyclonal Antibodies Primary Antibodies Selection Loading Controls

Guidelines of Primary Antibodies for Western Blotting

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Western blotting Monoclonal antibodies Recombinant Antibodies Polyclonal Antibodies Primary Antibodies Selection Loading Controls

高分子量蛋白质印迹法

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免疫印迹生物缓冲液蛋白质印迹高分子量蛋白大分子蛋白蛋白质电泳 WB抗体

Protocol of Western Blotting For High Molecular Weights

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Western blotting Biological buffer Immunoblotting Protein Electrophoresis High Molecular Weights large molecular proteins WB antibody

Protocol of Western Blotting For High Molecular Weights

Categories: 实验方案（Protocols）

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Western blotting Biological buffer Immunoblotting Protein Electrophoresis High Molecular Weights large molecular proteins WB antibody

Protocol of Western Blotting For High Molecular Weights

Categories: 实验方案（Protocols）

探索主题:

Western blotting Biological buffer Immunoblotting Protein Electrophoresis High Molecular Weights large molecular proteins WB antibody

Protocol of Western Blotting For High Molecular Weights

Categories: 实验方案（Protocols）

探索主题:

Western blotting Biological buffer Immunoblotting Protein Electrophoresis High Molecular Weights large molecular proteins WB antibody

引用文献

1. Graves, B J BJ and 5 more authors.. (1990) Structure of interleukin 1 alpha at 2.7-A resolution.. Biochemistry, (20): [PMID:2346741]
2. March, C J CJ and 9 more authors.. (1985) Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs.. Nature, [PMID:2989698]
3. Furutani, Y Y and 9 more authors.. (1985) Cloning and characterization of the cDNAs for human and rabbit interleukin-1 precursor.. Nucleic acids research, (26): [PMID:2994016]
4. Zsebo, K M KM and 6 more authors.. (1988) Effects of hematopoietin-1 and interleukin 1 activities on early hematopoietic cells of the bone marrow.. Blood, [PMID:3281727]
5. Gubler, U U and 9 more authors.. (1986) Recombinant human interleukin 1 alpha: purification and biological characterization.. Journal of immunology (Baltimore, Md. : 1950), (1): [PMID:3485152]
6. Furutani, Y Y and 6 more authors.. (1986) Complete nucleotide sequence of the gene for human interleukin 1 alpha.. Nucleic acids research, (25): [PMID:3486405]
7. Nishida, T T and 7 more authors.. (1987) cDNA cloning of IL-1 alpha and IL-1 beta from mRNA of U937 cell line.. Biochemical and biophysical research communications, (27): [PMID:3493774]
8. Stevenson, F T FT, Bursten, S L SL, Fanton, C C, Locksley, R M RM and Lovett, D H DH.. (1993) The 31-kDa precursor of interleukin 1 alpha is myristoylated on specific lysines within the 16-kDa N-terminal propiece.. Proceedings of the National Academy of Sciences of the United States of America, (1): [PMID:8346241]
9. Nicklin, Martin J H MJ and 5 more authors.. (2002) A sequence-based map of the nine genes of the human interleukin-1 cluster.. Genomics, [PMID:11991722]
10. Spiekstra, S W SW and 10 more authors.. (2005) Induction of cytokine (interleukin-1alpha and tumor necrosis factor-alpha) and chemokine (CCL20, CCL27, and CXCL8) alarm signals after allergen and irritant exposure.. Experimental dermatology, [PMID:15679580]
11. Hillier, Ladeana W LW and 121 more authors.. (2005) Generation and annotation of the DNA sequences of human chromosomes 2 and 4.. Nature, (7): [PMID:15815621]
12. Brikos, Constantinos C, Wait, Robin R, Begum, Shajna S, O'Neill, Luke A J LA and Saklatvala, Jeremy J.. (2007) Mass spectrometric analysis of the endogenous type I interleukin-1 (IL-1) receptor signaling complex formed after IL-1 binding identifies IL-1RAcP, MyD88, and IRAK-4 as the stable components.. Molecular & cellular proteomics : MCP, [PMID:17507369]
13. Mohan, Sepuru K SK and Yu, Chin C.. (2011) The IL1alpha-S100A13 heterotetrameric complex structure: a component in the non-classical pathway for interleukin 1alpha secretion.. The Journal of biological chemistry, (22): [PMID:21270123]
14. Cronstein, Bruce N BN and Sunkureddi, Prashanth P.. (2013) Mechanistic aspects of inflammation and clinical management of inflammation in acute gouty arthritis.. Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, [PMID:23319019]
15. Tran, Tran H TH, Pham, Jacqueline T JT, Shafeeq, Hira H, Manigault, Kendra R KR and Arya, Vibhuti V.. (2013) Role of interleukin-1 inhibitors in the management of gout.. Pharmacotherapy, [PMID:23553601]
16. Cohen, Idan I and 24 more authors.. (2015) IL-1α is a DNA damage sensor linking genotoxic stress signaling to sterile inflammation and innate immunity.. Scientific reports, (6): [PMID:26439902]
17. Kotenko, S V SV, Bulenkov, M T MT, Veĭko, V P VP, Epishin, S M SM and Lomakin, I B IB.. (1989) [Cloning of the cDNA coding for human prointerleukin-1 alpha and prointerleukin-1 beta].. Doklady Akademii nauk SSSR, [PMID:2635664]

溶液计算器

摩尔浓度计算器

计算溶液所需的质量、体积或浓度。

质量

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体积

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g/mol

稀释计算器

计算配制储备溶液所需的稀释度。

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复溶计算器

复溶计算器允许您快速计算试剂的体积，以复溶小瓶。只需输入试剂的质量和目标浓度，计算器将确定其余部分。

体积（添加到小瓶中）

质量（小瓶）

所需的复溶浓度

IL-1 alpha Mouse mAb

库存信息

库存信息

库存信息

库存信息

基本信息

产品属性

关联靶点（人）

作用机制

图片

应用

质检证书（CoA,COO,BSE/TSE 和分析图谱)

技术文档和文章

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器

IL-1 alpha Mouse mAb

库存信息

库存信息

库存信息

库存信息

基本信息

产品属性

关联靶点（人）

作用机制

图片

应用

质检证书（CoA,COO,BSE/TSE 和分析图谱)

技术文档和文章

相关产品

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器