货号 (SKU)

包装规格

是否现货

价格

数量

Ab096159-10μl

10μl

现货

Ab096159-50μl

50μL

现货

Ab096159-100μl

100μL

期货

Ab096159-1ml

1ml

期货

基本信息

产品名称	c-Fos Mouse mAb
别名	c-Fos小鼠单克隆抗体 \| c-Fos小鼠单抗
英文别名	Cellular oncogene fos \| G0/G1 switch regulatory protein 7
规格或纯度	ExactAb™, Validated, 1.0 mg/mL
宿主种属	小鼠(Mouse)
特异性	c-Fos
种属反应性	人(Human),大鼠(Rat),猴(Monkey)
免疫原	Purified recombinant human FOS protein fragments expressed in E.coli (AA 1-380).
阳性对照	WB: HeLa (serum starved 36 hours, then treated with 20% FBS for 2 hours) cell lysates.
偶联	Unconjugated

产品属性

克隆类型	单克隆抗体
克隆号	7D6-A9-D4
Format	Whole IgG
亚型	Mouse IgG1
轻链亚型	kappa
SDS-PAGE	150 kDa
纯化方法	Protein G purified
物理外观	Liquid
储存缓冲液	10mM PBS, 50% Glycerol, 0.5% BSA, 0.02% Sodium azide, pH 7.3
防腐剂	0.02% Sodium azide
浓度	1.0 mg/mL
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	4°C 短期储存（1-2 周）。-20°C下长期保存（24个月）。收货后建议分装。避免冷冻/解冻循环。
分子类型	抗体

关联靶点（人）

FOS Tbio 原癌基因c-Fos(Proto-oncogene c-Fos) (0 活性数据)

点击查看靶蛋白信息： FOS

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

图片

Western Blot: c-Fos Mouse mAb (Ab096159)

c-Fos Mouse mAb (Ab096159) - Western Blot
All lanes: c-Fos Mouse mAb (Ab096159) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab179001) at 1/20000 dilution
Predicted band size: 41 kDa
Observed band size: 67 kDa
Exposure time: 91.4 s

应用

应用名称	稀释比例
WB	1/500-1/1000

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Guidelines of Primary Antibodies for Western Blotting

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高分子量蛋白质印迹法

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Protocol of Western Blotting For High Molecular Weights

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Western blotting Biological buffer Immunoblotting Protein Electrophoresis High Molecular Weights large molecular proteins WB antibody

Protocol of Western Blotting For High Molecular Weights

Categories: 实验方案（Protocols）

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Western blotting Biological buffer Immunoblotting Protein Electrophoresis High Molecular Weights large molecular proteins WB antibody

Protocol of Western Blotting For High Molecular Weights

Categories: 实验方案（Protocols）

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Western blotting Biological buffer Immunoblotting Protein Electrophoresis High Molecular Weights large molecular proteins WB antibody

可替换产品

引用文献

1. Ye N, Ding Y, Wild C, Shen Q, Zhou J.. (2014) Small molecule inhibitors targeting activator protein 1 (AP-1).. J Med Chem, 57 (16): (6930-6948). [PMID:24831826] [10.1021/jm5004733]
2. Roux, P P and 6 more authors.. (1991) Retrovirus-mediated gene transfer of a human c-fos cDNA into mouse bone marrow stromal cells.. Oncogene, [PMID:1658710]
3. Nakabeppu, Y Y and Nathans, D D.. (1989) The basic region of Fos mediates specific DNA binding.. The EMBO journal, (1): [PMID:2511004]
4. Hai, T W TW, Liu, F F, Coukos, W J WJ and Green, M R MR.. (1989) Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers.. Genes & development, [PMID:2516827]
5. van Straaten, F F, Müller, R R, Curran, T T, Van Beveren, C C and Verma, I M IM.. (1983) Complete nucleotide sequence of a human c-onc gene: deduced amino acid sequence of the human c-fos protein.. Proceedings of the National Academy of Sciences of the United States of America, [PMID:6574479]
6. Glover, J N JN and Harrison, S C SC.. (1995) Crystal structure of the heterodimeric bZIP transcription factor c-Fos-c-Jun bound to DNA.. Nature, (19): [PMID:7816143]
7. Zhang, Y Y, Feng, X H XH and Derynck, R R.. (1998) Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription.. Nature, (27): [PMID:9732876]
8. Heilig, Roland R and 98 more authors.. (2003) The DNA sequence and analysis of human chromosome 14.. Nature, (6): [PMID:12508121]
9. Bossis, Guillaume G and 9 more authors.. (2005) Down-regulation of c-Fos/c-Jun AP-1 dimer activity by sumoylation.. Molecular and cellular biology, [PMID:16055710]
10. Portal, M M MM, Ferrero, G O GO and Caputto, B L BL.. (2007) N-Terminal c-Fos tyrosine phosphorylation regulates c-Fos/ER association and c-Fos-dependent phospholipid synthesis activation.. Oncogene, (24): [PMID:17160021]
11. Jakobs, Astrid and 5 more authors.. (2007) Ubc9 fusion-directed SUMOylation identifies constitutive and inducible SUMOylation.. Nucleic acids research, [PMID:17709345]
12. Mayya, Viveka V and 7 more authors.. (2009) Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.. Science signaling, (18): [PMID:19690332]
13. Fiebich, Bernd L BL and 6 more authors.. (2012) Pseudoephedrine inhibits T-cell activation by targeting NF-κB, NFAT and AP-1 signaling pathways.. Immunopharmacology and immunotoxicology, [PMID:21631396]
14. Ferrero, G O GO, Velazquez, F N FN and Caputto, B L BL.. (2012) The kinase c-Src and the phosphatase TC45 coordinately regulate c-Fos tyrosine phosphorylation and c-Fos phospholipid synthesis activation capacity.. Oncogene, (12): [PMID:22105363]
15. Hendriks, Ivo A; Treffers, Louise W; Verlaan-de Vries, Matty; Olsen, Jesper V and Vertegaal, Alfred C O.. (2015) SUMO-2 Orchestrates Chromatin Modifiers in Response to DNA Damage.. Cell reports, (17): [PMID:25772364]

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c-Fos Mouse mAb

库存信息

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溶液计算器

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c-Fos Mouse mAb

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