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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab094310-10μg |
10μg |
现货 ![]() |
| |
| Ab094310-50μg |
50μg |
现货 ![]() |
| |
| Ab094310-100μg |
100μg |
现货 ![]() |
| |
| Ab094310-1mg |
1mg |
期货 ![]() |
|
| 产品名称 | CD23 Mouse mAb |
|---|---|
| 别名 | CD23/FcεRII单克隆抗体 | CD23抗体 | Anti-CD23抗体 | CD23小鼠单克隆抗体 | CD23小鼠单抗 |
| 英文别名 | BLAST-2 | CD23 | CD23A | CD23CD23 antigen | CLEC4J | CLEC4JC-type lectin domain family 4 member J | C-type lectin domain family 4, member J | Fc epsilon RII | Fc fragment of IgE, low affinity II, receptor for (CD23) | FCE2Fc fragment of IgE, low affinity |
| 规格或纯度 | 无载体, ExactAb™, 无叠氮钠, 已验证, 见COA |
| 宿主种属 | 小鼠(Mouse) |
| 特异性 | CD23 |
| 种属反应性 | 人(Human) |
| 免疫原 | Recombinant protein of human CD23 |
| 阳性对照 | Flow: Human peripheral blood lymphocytes. |
| 偶联 | Unconjugated |
| 克隆类型 | 单克隆抗体 |
|---|---|
| 克隆号 | EBVCS-5 |
| Format | Whole IgG |
| 亚型 | Mouse IgG1 |
| 轻链亚型 | kappa |
| SDS-PAGE | 150 kDa |
| 纯化方法 | Protein G purified |
| 物理外观 | Liquid |
| 储存缓冲液 | 10mM PBS, pH 7.2-7.4 |
| 防腐剂 | No |
| 浓度 | 见COA |
| 储存温度 | 2-8°C储存 |
| 运输条件 | 冰袋运输 |
| 稳定性与储存 | 4°C 下运输。4°C 长期保存(12 个月)。收货后建议分装。 |
| 分子类型 | 抗体 |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
CD23 Mouse mAb (Ab094310) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD23 with CD23 Mouse mAb (Ab094310) conjugated with biotin (right panel) at 0.1 μg/mL for 1 hour at 4°C, compared with mouse IgG (Ab170221) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).
CD23 Mouse mAb (Ab094310) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD23 (red) with CD23 Mouse mAb (Ab094310) conjugated with biotin at 0.1 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Isotype control, mouse IgG (Ab170221) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.
CD23 Mouse mAb (Ab094310) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD23 (red) with CD23 Mouse mAb (Ab094310) at 0.1 μg/mL for 1 hour at 4°C. AffiniPure Goat anti-Mouse IgG, Fcγ fragment specific (AF647) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.
| 应用名称 | 稀释比例 |
|---|---|
| Flow Cytometry | 1μg/100w cells |
通过匹配包装上的批号来查找并下载产品的 COA,每批产品都进行了严格的验证,您可放心使用!
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
| 分析证书 | Ab094310 | |
| 分析证书 | Ab094310 | |
| 分析证书 | Ab094310 |
¥175.92
¥399.92
¥329.90
¥335.92
¥175.92
| 1. Yokota A, Kikutani H, Tanaka T, Sato R, Barsumian EL, Suemura M, Kishimoto T. (1988) Two species of human Fc epsilon receptor II (Fc epsilon RII/CD23): tissue-specific and IL-4-specific regulation of gene expression.. Cell, 55 (4): (611-8). [PMID:2972386] |
| 2. Rose, K K and 8 more authors.. (1992) Partial characterization of natural and recombinant human soluble CD23.. The Biochemical journal, (15): [PMID:1417742] |
| 3. Pirron, U U, Schlunck, T T, Prinz, J C JC and Rieber, E P EP.. (1990) IgE-dependent antigen focusing by human B lymphocytes is mediated by the low-affinity receptor for IgE.. European journal of immunology, [PMID:2167225] |
| 4. Kikutani, H H and 9 more authors.. (1986) Molecular structure of human lymphocyte receptor for immunoglobulin E.. Cell, (5): [PMID:2877743] |
| 5. Ikuta, K K and 7 more authors.. (1987) Human lymphocyte Fc receptor for IgE: sequence homology of its cloned cDNA with animal lectins.. Proceedings of the National Academy of Sciences of the United States of America, [PMID:2949326] |
| 6. Lüdin, C C and 8 more authors.. (1987) Cloning and expression of the cDNA coding for a human lymphocyte IgE receptor.. The EMBO journal, [PMID:3034567] |
| 7. Vouldoukis, I I and 7 more authors.. (1995) The killing of Leishmania major by human macrophages is mediated by nitric oxide induced after ligation of the Fc epsilon RII/CD23 surface antigen.. Proceedings of the National Academy of Sciences of the United States of America, (15): [PMID:7544003] |
| 8. Padlan, E A EA and Helm, B A BA.. (1993) Modeling of the lectin-homology domains of the human and murine low-affinity Fc epsilon receptor (Fc epsilon RII/CD23).. Receptor, [PMID:8142907] |
| 9. Bajorath, J J and Aruffo, A A.. (1996) Structure-based modeling of the ligand binding domain of the human cell surface receptor CD23 and comparison of two independently derived molecular models.. Protein science : a publication of the Protein Society, [PMID:8745401] |
| 10. Grimwood, Jane J and 97 more authors.. (2004) The DNA sequence and biology of human chromosome 19.. Nature, (1): [PMID:15057824] |
| 11. Hibbert, Richard G RG and 9 more authors.. (2005) The structure of human CD23 and its interactions with IgE and CD21.. The Journal of experimental medicine, (19): [PMID:16172256] |
| 12. Wurzburg, Beth A BA, Tarchevskaya, Svetlana S SS and Jardetzky, Theodore S TS.. (2006) Structural changes in the lectin domain of CD23, the low-affinity IgE receptor, upon calcium binding.. Structure (London, England : 1993), [PMID:16765898] |
| 13. Lemieux, George A GA and 9 more authors.. (2007) The low affinity IgE receptor (CD23) is cleaved by the metalloproteinase ADAM10.. The Journal of biological chemistry, (18): [PMID:17389606] |
| 14. Pathan, Nuzhat I NI and 5 more authors.. (2008) Mediation of apoptosis by and antitumor activity of lumiliximab in chronic lymphocytic leukemia cells and CD23+ lymphoma cell lines.. Blood, (1): [PMID:18032710] |
| 15. Ivaldi, Corinne C and 6 more authors.. (2012) Proteomic analysis of S-acylated proteins in human B cells reveals palmitoylation of the immune regulators CD20 and CD23.. PloS one, [PMID:22615937] |
| 16. Hersheson, Joshua J and 17 more authors.. (2013) Mutations in the autoregulatory domain of β-tubulin 4a cause hereditary dystonia.. Annals of neurology, [PMID:23424103] |