PSA Mouse mAb

COA

级别和纯度:

见COA

应用:

Capture Antibody
CLIA
ELISA

宿主种属: 小鼠(Mouse)
种属反应性: 人(Human)
亚型: Mouse IgG1
克隆号: 3D2
偶联: Unconjugated

有货

库存信息

关闭

库存信息

关闭

库存信息

关闭

库存信息

关闭

货号 (SKU)	包装规格	是否现货
Ab005494-10μg	10μg	现货
Ab005494-50μg	50μg	现货
Ab005494-100μg	100μg	现货
Ab005494-1mg	1mg	期货

查看相关系列

点击查看靶蛋白信息: KLK3

Accession#:P07288 (5) Gene ID:354 (5) KLK3 (5) PSA (4)

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基本信息

产品名称	PSA Mouse mAb
别名	PSA 小鼠单克隆抗体 \| PSA 小鼠单抗
英文别名	EC 3.4.21.77 \| Gamma-seminoprotein \| Kallikrein-3 \| P-30 antigen \| PSA \| Semenogelase \| Seminin
规格或纯度	无载体, ExactAb™, 无叠氮钠, 已验证, 见COA
宿主种属	小鼠(Mouse)
特异性	PSA
应用	ELISA,CLIA
种属反应性	人(Human)
免疫原	Native protein
偶联	Unconjugated

产品属性

抗体类型	Primary antibody
克隆类型	单克隆抗体
克隆号	3D2
Format	Whole IgG
亚型	IgG1
SDS-PAGE	150 kDa
纯化方法	Affinity purified
配对抗体	[Ab005424] Anti-h PSA as Detection antibody in ELISA, CLIA
来源	Hybridoma supernatant
物理外观	Liquid
储存缓冲液	10mM PB+150mM NaCl+0.1% ProClin 300，pH7.4
防腐剂	0.1% ProClin 300
浓度	见COA
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	Store at -20±5℃ for three years. Avoid repeated freeze/thaw cycles.
分子类型	抗体

关联靶点（人）

KLK3 Tclin 前列腺特异抗原(Prostate-specific antigen) (0 活性数据)

点击查看靶蛋白信息： KLK3

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

图片

Relevance of detection results between aladdin Antibody Pair (Ab005494 & Ab005424) and Roche in CLIA

Relevance of detection results between aladdin Antibody Pair (Ab005494 & Ab005424) and Roche in CLIA

· Capture antibody: PSA Mouse mAb (Ab005494) at 1.0 μg/mL.

· Detection antibody: PSA Mouse mAb (Ab005424) at 1.0 μg/mL.

· Linear Range: 0-50 ng/mL, R² ≥ 0.95.

应用

应用名称	稀释比例
ELISA	1 μg/mL
CLIA	1 μg/mL

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到3个结果

批号(Lot Number)	证书类型	货号
ZJ24F1011957	分析证书	Ab005494
ZJ23F0500213	分析证书	Ab005494
ZJ23F0500212	分析证书	Ab005494

技术文档和文章

石蜡样品的免疫组化染色方案（IHC-P）

Categories: 实验方案（Protocols）

探索主题:

单克隆抗体石蜡切片免疫组化染色

RNA斑点杂交实验方案

Categories: 实验方案（Protocols）

探索主题:

一抗二抗蛋白质电泳和蛋白质印迹斑点杂交

RNA dot blot protocol

Categories: 实验方案（Protocols）

探索主题:

Protein Electrophoresis & Western Blotting Dot Blotting Primary antibodies Secondary Antibodies

RNA dot blot protocol

Categories: 实验方案（Protocols）

探索主题:

Protein Electrophoresis & Western Blotting Dot Blotting Primary antibodies Secondary Antibodies

可替换产品

引用文献

1. Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P et al.. (2004) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).. Genome Res, 14 (10B): (2121-7). [PMID:15489334]
2. Kostova MB, Rosen DM, Chen Y, Mease RC, Denmeade SR. (2013) Structural optimization, biological evaluation, and application of peptidomimetic prostate specific antigen inhibitors.. J Med Chem, 56 (11): (4224-35). [PMID:23692593]
3. De Vita E, Schüler P, Lovell S, Lohbeck J, Kullmann S, Rabinovich E, Sananes A, Heßling B, Hamon V, Papo N et al.. (2018) Depsipeptides Featuring a Neutral P1 Are Potent Inhibitors of Kallikrein-Related Peptidase 6 with On-Target Cellular Activity.. J Med Chem, 61 (19): (8859-8874). [PMID:30212625]
4. LeBeau AM, Banerjee SR, Pomper MG, Mease RC, Denmeade SR.. (2009) Optimization of peptide-based inhibitors of prostate-specific antigen (PSA) as targeted imaging agents for prostate cancer.. Bioorg Med Chem, 17 (14): (4888-4893). [PMID:19541487] [10.1016/j.bmc.2009.06.012]
5. Santos JA, Kondo MY, Freitas RF, dos Santos MH, Ramalho TC, Assis DM, Juliano L, Juliano MA, Puzer L.. (2016) The natural flavone fukugetin as a mixed-type inhibitor for human tissue kallikreins.. Bioorg Med Chem Lett, 26 (5): (1485-1489). [PMID:26848109] [10.1016/j.bmcl.2016.01.039]
6. Wu X, Hu L.. (2016) Design and synthesis of peptide conjugates of phosphoramide mustard as prodrugs activated by prostate-specific antigen.. Bioorg Med Chem, 24 (12): (2697-2706). [PMID:27156193] [10.1016/j.bmc.2016.04.035]
7. Akinboye ES, Rosen MD, Bakare O, Denmeade SR.. (2017) Anticancer activities of emetine prodrugs that are proteolytically activated by the prostate specific antigen (PSA) and evaluation of in vivo toxicity of emetine derivatives.. Bioorg Med Chem, 25 (24): (6707-6717). [PMID:29153549] [10.1016/j.bmc.2017.11.015]
8. Bakthavatsalam S, Wiangnak P, George DJ, Zhang T, Franz KJ.. (2020) Dithiocarbamate prodrugs activated by prostate specific antigen to target prostate cancer.. Bioorg Med Chem Lett, 30 (11): (127148-127148). [PMID:32253061] [10.1016/j.bmcl.2020.127148]
9. Tang Q,Fu W,Zhang M,Wang E,Shan L,Chai X,Pang J,Wang X,Xu X,Xu L,Li D,Sheng R,Hou T. (2020) Novel androgen receptor antagonist identified by structure-based virtual screening, structural optimization, and biological evaluation.. Eur J Med Chem, 192 (112156-112156). [PMID:32114360] [10.1016/j.ejmech.2020.112156]
10. España, F F and 5 more authors.. (1991) Functionally active protein C inhibitor/plasminogen activator inhibitor-3 (PCI/PAI-3) is secreted in seminal vesicles, occurs at high concentrations in human seminal plasma and complexes with prostate-specific antigen.. Thrombosis research, (1): [PMID:1725227]
11. Watt, K W KW, Lee, P J PJ, M'Timkulu, T T, Chan, W P WP and Loor, R R.. (1986) Human prostate-specific antigen: structural and functional similarity with serine proteases.. Proceedings of the National Academy of Sciences of the United States of America, [PMID:2422647]
12. Lundwall, A A and Lilja, H H.. (1987) Molecular cloning of human prostate specific antigen cDNA.. FEBS letters, (20): [PMID:2436946]
13. Schulz, P P and 5 more authors.. (1988) Sequence of a cDNA clone encompassing the complete mature human prostate specific antigen (PSA) and an unspliced leader sequence.. Nucleic acids research, (11): [PMID:2456523]
14. Riegman, P H PH, Vlietstra, R J RJ, van der Korput, J A JA, Romijn, J C JC and Trapman, J J.. (1989) Characterization of the prostate-specific antigen gene: a novel human kallikrein-like gene.. Biochemical and biophysical research communications, (28): [PMID:2466464]
15. Digby, M M, Zhang, X Y XY and Richards, R I RI.. (1989) Human prostate specific antigen (PSA) gene: structure and linkage to the kallikrein-like gene, hGK-1.. Nucleic acids research, (11): [PMID:2467258]
16. Henttu, P P and Vihko, P P.. (1989) cDNA coding for the entire human prostate specific antigen shows high homologies to the human tissue kallikrein genes.. Biochemical and biophysical research communications, (28): [PMID:2470373]
17. Klobeck, H G HG, Combriato, G G, Schulz, P P, Arbusow, V V and Fittler, F F.. (1989) Genomic sequence of human prostate specific antigen (PSA).. Nucleic acids research, (25): [PMID:2471958]
18. and Lundwall, A A.. (1989) Characterization of the gene for prostate-specific antigen, a human glandular kallikrein.. Biochemical and biophysical research communications, (30): [PMID:2472789]
19. Schaller, J J and 5 more authors.. (1987) Isolation, characterization and amino-acid sequence of gamma-seminoprotein, a glycoprotein from human seminal plasma.. European journal of biochemistry, (30): [PMID:3691515]
20. Monne, M M, Croce, C M CM, Yu, H H and Diamandis, E P EP.. (1994) Molecular characterization of prostate-specific antigen messenger RNA expressed in breast tumors.. Cancer research, (15): [PMID:7527295]
21. Villoutreix, B O BO, Getzoff, E D ED and Griffin, J H JH.. (1994) A structural model for the prostate disease marker, human prostate-specific antigen.. Protein science : a publication of the Protein Society, [PMID:7535613]
22. Baffa, R R, Moreno, J G JG, Monne, M M, Veronese, M L ML and Gomella, L G LG.. (1996) A comparative analysis of prostate-specific antigen gene sequence in benign and malignant prostate tissue.. Urology, [PMID:8677566]
23. Coombs, G S GS and 8 more authors.. (1998) Substrate specificity of prostate-specific antigen (PSA).. Chemistry & biology, [PMID:9751643]
24. Gan, L L and 8 more authors.. (2000) Sequencing and expression analysis of the serine protease gene cluster located in chromosome 19q13 region.. Gene, (17): [PMID:11054574]
25. Grimwood, Jane J and 97 more authors.. (2004) The DNA sequence and biology of human chromosome 19.. Nature, (1): [PMID:15057824]
26. Zhang, Zemin Z and Henzel, William J WJ.. (2004) Signal peptide prediction based on analysis of experimentally verified cleavage sites.. Protein science : a publication of the Protein Society, [PMID:15340161]
27. Ménez, Renée R and 6 more authors.. (2008) Crystal structure of a ternary complex between human prostate-specific antigen, its substrate acyl intermediate and an activating antibody.. Journal of molecular biology, (29): [PMID:18187150]
28. Végvári, Akos A and 6 more authors.. (2013) Identification of a novel proteoform of prostate specific antigen (SNP-L132I) in clinical samples by multiple reaction monitoring.. Molecular & cellular proteomics : MCP, [PMID:23842001]

溶液计算器

摩尔浓度计算器

计算溶液所需的质量、体积或浓度。

质量

浓度

体积

分子量

g/mol

稀释计算器

计算配制储备溶液所需的稀释度。

浓度1（C1）

体积 1 (V1)

浓度 2 (C2)

体积 2 (V2)

复溶计算器

复溶计算器允许您快速计算试剂的体积，以复溶小瓶。只需输入试剂的质量和目标浓度，计算器将确定其余部分。

体积（添加到小瓶中）

质量（小瓶）

所需的复溶浓度

PSA Mouse mAb

库存信息

库存信息

库存信息

库存信息

基本信息

产品属性

关联靶点（人）

作用机制

图片

应用

质检证书（CoA,COO,BSE/TSE 和分析图谱)

技术文档和文章

相关产品

可替换产品

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器