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Recombinant RING1 Antibody - Primary antibody, specific to RING1, Rabbit IgG

COA COA
    Application:
  • WB
  • Host species: Rabbit
  • Reactive species: Human,Mouse
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab125377
Grouped product items
SKU Size
Availability
 Price Qty
Ab125377-10μl
10μl
2
$69.90
Ab125377-50μl
50μl
1
$189.90
Ab125377-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
Ab125377-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,599.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Recombinant; Rabbit anti Human RING1 Antibody; WB; Unconjugated

View related series
Click to view target information: RING1
Accession#:Q06587 (1) Gene ID:6015 (1) RING1 (1)

Basic Description

Product Name Recombinant RING1 Antibody - Primary antibody, specific to RING1, Rabbit IgG
Synonyms Ring1A antibody | E3 ubiquitin-protein ligase RING1 antibody | Polycomb complex protein RING1 antibody | Really interesting new gene 1 protein antibody | RING finger protein 1 antibody | Ring1 antibody | RING1_HUMAN antibody | Rnf1 antibody | Transcriptio
Specifications & Purity ExactAb™, Validated, Recombinant, 0.4 mg/mL
Host species Rabbit
Specificity RING1
Immunogen A synthetic peptide derived from human RING1 (AA 140-195)
Positive Control WB: Ramos, HeLa, LNCaP, MOLT-4, THP-1 and NIH/3T3 cell lysates.
Conjugation Unconjugated
Grade ExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human RING1 Antibody, Recombinant, could be used for WB and so on.

Application:
WB: 1/500-1/1000
Protein Function:
Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in × chromosome inactivation of female mammals. Essential component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex act via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility. Compared to RNF2/RING2, it does not have the main E3 ubiquitin ligase activity on histone H2A, and it may rather act as a modulator of RNF2/RING2 activity.

Product Properties

Isotype Rabbit IgG
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein A purified
Shape Liquid
Concentration 0.4 mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

RING1 Tbio E3 ubiquitin-protein ligase RING1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Images

Recombinant RING1 Antibody (Ab125377) - Western Blot
All lanes: Recombinant RING1 Antibody (Ab125377) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 42 kDa
Observed band size: 49, 50 kDa
Exposure time: 14.5 s

Application

Application Dilution info
WB

1/500-1/1000

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ24F0405041 Certificate of Analysis Apr 29, 2024 Ab125377
ZJ24F0405040 Certificate of Analysis Apr 29, 2024 Ab125377

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