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Recombinant RAB10 Antibody - Primary antibody, specific to RAB10, Rabbit IgG

COA COA
    Application:
  • IF/ICC
  • WB
  • Host species: Rabbit
  • Reactive species: Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab124097
Grouped product items
SKU Size
Availability
 Price Qty
Ab124097-10μl
10μl
5
$66.90
Ab124097-50μl
50μl
2
$199.90
Ab124097-100μl
100μl
1
$319.90
Ab124097-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,599.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Recombinant; Rabbit anti Human RAB10 Antibody; WB, ICC, IF; Unconjugated

View related series
Click to view target information: RAB10
Accession#:P61026 (1) Gene ID:10890 (1) RAB10 (1)

Basic Description

Product Name Recombinant RAB10 Antibody - Primary antibody, specific to RAB10, Rabbit IgG
Synonyms GTP binding protein RAB10 antibody | Rab10 antibody | RAB10 member RAS oncogene family antibody | RAB10_HUMAN antibody | Ras related GTP binding protein antibody | Ras related GTP binding protein RAB10 antibody | Ras-related protein Rab-10 antibody | Anti
Specifications & Purity ExactAb™, Validated, Recombinant, 0.7 mg/mL
Host species Rabbit
Specificity RAB10
Immunogen Recombinant protein of human RAB10 (AA 1-200).
Positive Control WB: C6, NIH/3T3, HeLa, A549, MCF7, HUVEC and A431 cell lysates. ICC/IF: A549 cells.
Conjugation Unconjugated
Grade ExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human RAB10 Antibody, Recombinant, could be used for WB, ICC, IF and so on.
Application:
· WB: 1/500-1/1000
· ICC/IF: 1/50-1/200
Protein Function
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). That Rab is mainly involved in the biosynthetic transport of proteins from the Golgi to the plasma membrane. Regulates, for instance, SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane. In parallel, it regulates the transport of TLR4, a toll-like receptor to the plasma membrane and therefore may be important for innate immune response. Plays also a specific role in asymmetric protein transport to the plasma membrane within the polarized neuron and epithelial cells. In neurons, it is involved in axonogenesis through regulation of vesicular membrane trafficking toward the axonal plasma membrane while in epithelial cells, it regulates transport from the Golgi to the basolateral membrane. Moreover, may play a role in the basolateral recycling pathway and in phagosome maturation. According to PubMed:23263280, may play a role in endoplasmic reticulum dynamics and morphology controlling tubulation along microtubules and tubules fusion.

Product Properties

Isotype Rabbit IgG
SDS-PAGE 150 kD
Purification Method Antigen affinity purified
Shape Liquid
Concentration 0.7 mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

RAB10 Tbio Ras-related protein Rab-10 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Recombinant RAB10 Antibody (Ab124097) - Western Blot
All lanes: Recombinant RAB10 Antibody (Ab124097) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 23 kDa
Observed band size: 25 kDa
Exposure time: 24.3 s

Recombinant RAB10 Antibody (Ab124097) - IF
Immunocytochemistry analysis of Rab10 (green) in A549 cells using Recombinant RAB10 Antibody (Ab124097) and cells were counterstained with DAPI (blue).

Application

Application Dilution info
WB

1/500-1/1000
IF/ICC

1/50-1/200

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F0901063 Certificate of Analysis Sep 18, 2023 Ab124097
ZJ23F0901062 Certificate of Analysis Sep 18, 2023 Ab124097

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