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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab111159-10μl
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10μl |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$69.90
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Ab111159-50μl
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50μl |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$199.90
|
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Ab111159-100μl
|
100μl |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$319.90
|
|
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Ab111159-1ml
|
1ml |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,699.90
|
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Recombinant; Rabbit anti Human IRAK4 Antibody; WB, IF/ICC; Unconjugated
| Product Name | Recombinant IRAK4 Antibody - Primary antibody, specific to IRAK4, Rabbit IgG |
|---|---|
| Synonyms | EC 2.7.11 | EC 2.7.11.1 | interleukin-1 receptor-associated kinase 4 | IPD1 | IRAK4 | IRAK-4 | NY-REN-64 | REN64 | Renal carcinoma antigen NY-REN-64 | IL-1 receptor-associated kinase 4 antibody | Interleukin 1 receptor associated kinase 4 mutant form 1 an |
| Specifications & Purity | Recombinant, ExactAb™, Validated, See COA |
| Biochemical and Physiological Mechanisms | Required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. Phosphorylates IRAK1. |
| Host species | Rabbit |
| Specificity | IRAK4 |
| Immunogen | A synthetic peptide derived from human IRAK4 (AA 1-64) |
| Positive Control | WB: K562, HeLa and Jurkat cell lysates. IF/ICC: HeLa cells. |
| Conjugation | Unconjugated |
| Grade | ExactAb™, Recombinant, Validated |
| Product Description |
Rabbit anti Human IRAK4 Antibody, Recombinant, could be used for WB, IF/ICC and so on. |
| Isotype | Rabbit IgG |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 0.02% Sodium azide |
| Purification Method | Protein A purified |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Recombinant IRAK4 Antibody (Ab111159) - Western Blot
All lanes: Recombinant IRAK4 Antibody (Ab111159) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/30000 dilution
Predicted band size: 52 kDa
Observed band size: 52 kDa
Exposure time: 14.1 s
Recombinant IRAK4 Antibody (Ab111159) - Western Blot
All lanes: Recombinant IRAK4 Antibody (Ab111159) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/30000 dilution
Predicted band size: 52 kDa
Observed band size: 52 kDa
Exposure time: 14.1 s
Recombinant IRAK4 Antibody (Ab111159) - IF/ICC
Immunofluorescent analysis of HeLa cells using Recombinant IRAK4 Antibody (Ab111159) at 1/50 dilution.
Recombinant IRAK4 Antibody (Ab111159) - IF/ICC
Immunofluorescent analysis of HeLa cells using Recombinant IRAK4 Antibody (Ab111159) at 1/150 dilution.
| Application | Dilution info |
|---|---|
| IF/ICC |
1/50-1/200
|
| WB |
1/1000-1/2000
|