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Recombinant Cytochrome P450 17A1/CYP17A1 Antibody - Primary antibody, specific to Cytochrome P450 17A1/CYP17A1, Rabbit IgG

    Application:
  • IF/ICC
  • IHC
  • WB
  • Host species: Rabbit
  • Reactive species: Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab098713
Grouped product items
SKU Size
Availability
Price Qty
Ab098713-10μl
10μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$59.90
Ab098713-50μl
50μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$189.90
Ab098713-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$309.90
Ab098713-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,499.90

Recombinant; Rabbit anti Human Cytochrome P450 17A1/CYP17A1 Antibody; WB, IHC, ICC, IF; Unconjugated

Basic Description

Product Name Recombinant Cytochrome P450 17A1/CYP17A1 Antibody - Primary antibody, specific to Cytochrome P450 17A1/CYP17A1, Rabbit IgG
Synonyms 17-alpha-hydroxyprogesterone aldolase | CYPXVII | Cytochrome P450 17A1 | Cytochrome P450c17 | Cytochrome P450-C17 | EC 1.14.14.19 | Steroid 17-alpha-monooxygenase | 20 lyase antibody | CP17A_HUMAN antibody | CPT7 antibody | CYP17 antibody | CYP17A1 antibo
Specifications & Purity ExactAb™, Validated, Recombinant, 0.5 mg/mL
Host species Rabbit
Specificity Cytochrome P450 17A1/CYP17A1
Immunogen A synthetic peptide derived from human Cytochrome P450 17A1/CYP17A1 (AA 133-147).
Positive Control WB: Mouse testis, K562, Hep G2, Jurkat, NIH/3T3 and C6 lysates. IHC: Mouse kidney tissue. IF/ICC: HeLa cells.
Conjugation Unconjugated
Grade ExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human Cytochrome P450 17A1/CYP17A1 Antibody, Recombinant, could be used for WB, IHC, ICC, IF and so on.
Application:
WB: 1/500-1/1000
IHC: 1/50-1/100
ICC/IF: 1/50-1/200
Protein Function:
Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty.

Product Properties

Isotype Rabbit IgG
SDS-PAGE 150 kDa
Purification Method Antigen affinity purified
Shape Liquid
Concentration 0.5 mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

CYP17A1 Tclin Steroid 17-alpha-hydroxylase/17,20 lyase (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Recombinant Cytochrome P450 17A1/CYP17A1 Antibody (Ab098713) - Western Blot
All lanes: Recombinant Cytochrome P450 17A1/CYP17A1 Antibody (Ab098713) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 57 kDa
Observed band size: 53 kDa
Exposure time: 42.5 s

Recombinant Cytochrome P450 17A1/CYP17A1 Antibody (Ab098713) - Western Blot
All lanes: Recombinant Cytochrome P450 17A1/CYP17A1 Antibody (Ab098713) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 57 kDa
Observed band size: 53 kDa
Exposure time: 42.5 s


Recombinant Cytochrome P450 17A1/CYP17A1 Antibody (Ab098713) - IHC
Immunohistochemistry analysis of paraffin-embedded mouse kidney using Recombinant Cytochrome P450 17A1/CYP17A1 Antibody (Ab098713). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Recombinant Cytochrome P450 17A1/CYP17A1 Antibody (Ab098713) - IF/ICC
Immunocytochemistry analysis of Cytochrome P450 17A1(green) in HeLa cells using Recombinant Cytochrome P450 17A1/CYP17A1 Antibody (Ab098713), and DAPI(blue).

Application

Application Dilution info
IF/ICC

1/50-1/200

IHC

1/50 - 1/100

WB

1/500-1/1000

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

Reviews

Customer Reviews

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