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Recombinant Insulin degrading enzyme/IDE Antibody - Primary antibody, specific to IDE, Rabbit IgG

    Application:
  • IHC
  • WB
  • Host species: Rabbit
  • Reactive species: Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab110716
Grouped product items
SKU Size
Availability
Price Qty
Ab110716-10μl
10μl
1
$69.90
Ab110716-50μl
50μl
1
$199.90
Ab110716-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$279.90
Ab110716-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,699.90

Recombinant; Rabbit anti Human Insulin degrading enzyme/IDE Antibody; WB, IHC; Unconjugated

Basic Description

Product Name Recombinant Insulin degrading enzyme/IDE Antibody - Primary antibody, specific to IDE, Rabbit IgG
Synonyms Abeta-degrading protease | EC 3.4.24 | EC 3.4.24.56 | FLJ35968 | IDE | INSDEGM | Insulin protease | Insulinase | insulin-degrading enzyme | Insulysin | BC2 | IDE_HUMAN | OTTHUMP00000020097 | Abeta-degrading protease antibody | FLJ35968 antibody | Ide anti
Specifications & Purity ExactAb™, Validated, Recombinant, 0.2 mg/mL
Host species Rabbit
Specificity IDE
Immunogen A synthetic peptide derived from human IDE (AA 56-69)
Positive Control WB: HeLa, A549, U-2 OS, Hep G2, K562, A375, NIH/3T3 and C6 cell lysates. IHC: Human lung cancer tissue.
Conjugation Unconjugated
Grade ExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human Insulin degrading enzyme/IDE Antibody, Recombinant, could be used for WB, IHC and so on.
Protein Function
Plays a role in the cellular breakdown of insulin, IAPP, glukagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia.

Product Properties

Isotype Rabbit IgG
SDS-PAGE 150 kDa
Purification Method Antigen affinity purified
Shape Liquid
Concentration 0.2 mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

IDE Tchem Insulin-degrading enzyme (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Recombinant Insulin degrading enzyme/IDE Antibody (Ab110716) - Western Blot
All lanes: Recombinant Insulin degrading enzyme/IDE Antibody (Ab110716) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 118 kDa
Observed band size: 106 kDa
Exposure time: 2.9 s

Recombinant Insulin degrading enzyme/IDE Antibody (Ab110716) - IHC
Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Recombinant Insulin degrading enzyme/IDE Antibody (Ab110716). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Application

Application Dilution info
IHC

1/50 - 1/100

WB

1/500-1/1000

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ24F0809194 Certificate of Analysis Aug 05, 2024 Ab110716
ZJ24F0809193 Certificate of Analysis Aug 05, 2024 Ab110716

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