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Recombinant EWSR1/EWS Antibody - Primary antibody, specific to EWSR1/EWS, Rabbit IgG

COA COA
    Application:
  • IF/ICC
  • WB
  • Host species: Rabbit
  • Reactive species: Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab102460
Grouped product items
SKU Size
Availability
 Price Qty
Ab102460-10μl
10μl
1
$69.90
Ab102460-50μl
50μl
1
$199.90
Ab102460-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$289.90
Ab102460-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,699.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Recombinant; Rabbit anti Human EWSR1/EWS Antibody; WB, ICC, IF; Unconjugated

View related series
Click to view target information: ENO1 Click to view target information: EWSR1 Click to view target information: ARL17A
Accession#: Q01844 (1) EWS (1) EWSR1 (1) Gene lD: 2130 (1)

Basic Description

Product Name Recombinant EWSR1/EWS Antibody - Primary antibody, specific to EWSR1/EWS, Rabbit IgG
Synonyms EWS | EWS-FLI1 | bK984G1.4 | bK984G1.4 antibody | bK984G1.4 Ewing sarcoma breakpoint region 1 protein antibody | Ewing sarcoma breakpoint region 1 antibody | Ewing sarcoma breakpoint region 1 protein antibody | Ewings sarcoma EWS Fli1 type 1 oncogene anti
Specifications & Purity ExactAb™, Validated, Recombinant, 0.2 mg/mL
Host species Rabbit
Specificity EWSR1/EWS
Immunogen A synthetic peptide derived from human EWSR1 (AA 349-362)
Positive Control WB: HeLa, K562, MCF7, Jurkat, A431, NIH/3T3 and C6 cell lysates. ICC/IF: 293T cells.
Conjugation Unconjugated
Grade ExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human EWSR1/EWS Antibody, Recombinant, could be used for WB, ICC, IF and so on.
Application:
WB: 1/500-1/1000
ICC/IF: 1/50-1/200
Protein Function：
Might normally function as a repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

Product Properties

Isotype Rabbit IgG
SDS-PAGE 150 kDa
Purification Method Antigen affinity purified
Shape Liquid
Concentration 0.2 mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

ENO1 Tchem Alpha-enolase (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
EWSR1 Tbio RNA-binding protein EWS (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
ARL17A Tdark ADP-ribosylation factor-like protein 17 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
ENO1 Tchem Alpha enolase (27 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
EWSR1 Tbio RNA-binding protein EWS (2 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Recombinant EWSR1/EWS Antibody (Ab102460) - Western Blot
All lanes: Recombinant EWSR1/EWS Antibody (Ab102460) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 68 kDa
Observed band size: 92 kDa
Exposure time: 4.1 s 

Recombinant EWSR1/EWS Antibody (Ab102460) - IF/ICC
Immunocytochemistry analysis of EWSR1 (green) in 293T using Recombinant EWSR1/EWS Antibody (Ab102460) and DAPI (blue).

Application

Application Dilution info
IF/ICC

1/50-1/200

WB

1/500-1/1000

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

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