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免疫疾病靶点

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  1. Recombinant Human IL-6 Protein
      种属: 人(Human)    Accession #: P05231    
      表达系统: E. coli    蛋白标签: N-His    内毒素水平: <1.0 EU/μg    
      生物活性: Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is 0.123 ng/mL. Immobilized Recombinant Human IL-6 Protein (rp156005) at 1.0 μg/mL can bind MEDI-5117 (anti-IL-6) (Ab182698) with the EC50 of 13.84 ng/mL.    
  2. Recombinant Human IL-18 Protein
      种属: 人(Human)    Accession #: Q14116    
      表达系统: E. coli    蛋白标签: N-His    内毒素水平: <1.0 EU/μg    
      生物活性: 1. Immobilized Recombinant Human IL-18 Bpa Protein (rp169678) at 2.0 μg/mL can bind Recombinant Human IL-18 Protein (rp156177) with the EC50 of 24.67 ng/mL. 2. Measured by its binding ability in a functional ELISA. Immobilized human IL-18 (rp156177) at 2.0 μg/mL can bind GSK 1070806 (anti-IL-18) (Ab177855).    
  3. Recombinant Human IL-1β Protein
      种属: 人(Human)    Accession #: P01584    
      表达系统: E. coli    蛋白标签: No tag     内毒素水平: <1.0 EU/μg    
      生物活性: 1. Immobilized Recombinant Human IL-1β Protein (rp156012) at 5.0 μg/mL can bind Recombinant Human IL-1 RII Protein (rp181605) with the EC50 of 176.8 ng/mL. 2. Immobilized Recombinant Human IL-1β Protein (rp156012) at 1.0 μg/mL can bind Gevokizumab (anti-IL-1b) (Ab175856) with the EC50 of 52.68 ng/mL. 3. Immobilized Recombinant Human IL-1β Protein (rp156012) at 1.0 μg/mL can bind Canakinumab (Anti-IL-1b) (Ab170512) with the EC50 of 22.81 ng/mL.    
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