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Recombinant Human IL-33 Protein

  • 表达系统: E. coli
  • Accession #: O95760
  • 蛋白标签: No tag
  • 生物活性: Measured by its binding ability in a functional ELISA. Immobilized human IL-33 (rp169652) at 2 μg/mL can bind Etokimab (anti-IL-33) (Ab170468) with the EC50 of 20.97 ng/mL.
  • 内毒素水平: <1.0 EU/μg
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货号 (SKU) 包装规格 是否现货 价格 数量
rp169652-10μg
10μg 现货 Stock Image
rp169652-50μg
50μg 现货 Stock Image
rp169652-100μg
100μg 现货 Stock Image
rp169652-1mg
1mg 期货 Stock Image

基本描述

产品名称 Recombinant Human IL-33 Protein
别名 重组人IL-33蛋白 | 重组人 IL-33 蛋白
英文别名 C9orf26 | C9orf26chromosome 9 open reading frame 26 (NF-HEV) | DKFZp586H0523 | DVS27 | DVS27-related protein | IL1F11 | IL-1F11 | IL33 | IL-33 | interleukin 33 | Interleukin-1 family member 11 | interleukin-33 | NFHEV | NF-HEV | NF-HEVNFEHEV | Nuclear fac
规格或纯度 ActiBioPure™, Bioactive, Carrier Free, Azide Free, ≥95%(SDS-PAGE)
产品介绍


Purity:>95%, by SDS-PAGE visualized with Coomassie® Blue Staining.
Description:
Interleukin 33 (IL-33), also known as DVS27 or NF-HEV (Nuclear Factor from High Endothelial Venules), is a pro-inflammatory protein and a chromatin-associated cytokine of the IL-1 family with high sequence and structural similarity to IL-1 and IL-18. IL-33 protein is expressed highly and rather selectively by high endothelial venule endothelial cells (HEVECs) in human tonsils, Peyer's patches, and lymph nodes. IL-33 protein has transcriptional regulatory properties, and the researches suggested that IL-33 is a dual-function protein that might act both as a cytokine and as an intracellular nuclear factor. As a type 2 cytokines, IL-33 protein also play a pivotal role in helminthic infection and allergic disorders.

生物活性 Measured by its binding ability in a functional ELISA. Immobilized human IL-33 (rp169652) at 2 μg/mL can bind Etokimab (anti-IL-33) (Ab170468) with the EC50 of 20.97 ng/mL.
内毒素水平 <1.0 EU/μg
表达系统 E. coli
种属 人(Human)
氨基酸 112-270 aa
序列 GPSITGISPITEYLASLSTYNDQSITFALEDESYEIYVEDLKKDEKKDKVLLSYYESQHPSNESGDGVDGKMLMVTLSPTKDFWLHANNKEHSVELHKCEKPLPDQAFFVLHNMHSNCVSFECKTDPGVFIGVKDNHLALIKVDSSENLCTENILFKLSET
纯度 >95%(SDS-PAGE)
蛋白标签 No tag
无载体 Yes
无动物源 No
Accession # O95760
来源 重组表达
预测分子量 18.1 kDa
SDS-PAGE 16.3 kDa, reducing conditions; 16.3 kDa, non-reducing conditions

储存与运输

物理形态 冻干(Lyophilized)
储存缓冲液 Lyophilized from PBS, pH7.4
复溶 We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 在 -20°C 下可保存 1 年。避免冷冻/解冻循环。
分子类型 蛋白质

图片

Recombinant Human IL-33 Protein (rp169652) - ELISA
Measured by its binding ability in a functional ELISA. Immobilized human IL-33 (rp169652) at 2 μg/mL can bind Etokimab (anti-IL-33) (Ab170468) with the EC₅₀ of 20.97 ng/mL.

Recombinant Human IL-33 Protein (rp169652) - SDS-PAGE
2 μg/lane of Recombinant Human IL-33 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 16.3 kDa.

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批号(Lot Number) 证书类型 货号
ZJ24F0102686 分析证书 rp169652
ZJ24F0102687 分析证书 rp169652
ZJ24F0102688 分析证书 rp169652

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