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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab104034-10μl |
10μl |
现货 ![]() |
| |
| Ab104034-50μl |
50μL |
现货 ![]() |
| |
| Ab104034-100μl |
100μL |
现货 ![]() |
| |
| Ab104034-1ml |
1ml |
期货 ![]() |
|
| 产品名称 | FOXP1 Mouse mAb |
|---|---|
| 别名 | 叉头框蛋白P1单克隆抗体 | 抗FOXP1抗体 |
| 英文别名 | 12CC4 antibody | FLJ23741 antibody | Fork head related protein like B antibody | Forkhead box P1 antibody | Forkhead box protein P1 antibody | FOX P1 antibody | FOXP 1 antibody | foxp1 antibody | FOXP1_HUMAN antibody | Glutamine rich factor 1 antibody | h |
| 规格或纯度 | 无载体, ExactAb™, 无叠氮钠, 已验证, 见COA |
| 宿主种属 | 小鼠(Mouse) |
| 特异性 | FOXP1 |
| 种属反应性 | 人(Human),小鼠(Mouse) |
| 免疫原 | Recombinant FOXP1 expressed in E.coli (AA 461-671) |
| 阳性对照 | WB: RAW264.7, MCF7 and Raji cell lysates. |
| 偶联 | Unconjugated |
| 克隆类型 | 单克隆抗体 |
|---|---|
| 克隆号 | D4 |
| Format | Whole IgG |
| 亚型 | Mouse IgG2a |
| 轻链亚型 | kappa |
| SDS-PAGE | 150 kDa |
| 纯化方法 | Protein A and Protein G purified |
| 物理外观 | Liquid |
| 储存缓冲液 | 10mM PBS, 50% Glycerol, 0.05% Proclin 300, pH7.4 |
| 防腐剂 | 0.05% Proclin 300 |
| 浓度 | 见COA |
| 储存温度 | -20°C储存,避免反复冻融 |
| 运输条件 | 超低温冰袋运输 |
| 稳定性与储存 | 4℃ 短期储存(1-2 周)。-20℃长期保存(24 个月)。收货后建议分装。避免冷冻/解冻循环。 |
| 分子类型 | 抗体 |
FOXP1 Mouse mAb (Ab104034) - Western Blot
All lanes: FOXP1 Mouse mAb (Ab104034) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab138040) at 1/50000 dilution
Predicted band size: 75 kDa
Observed band size: 80 kDa
Exposure time: 200.0 s
| 应用名称 | 稀释比例 |
|---|---|
| WB | 0.5-2 µg/mL |
通过匹配包装上的批号来查找并下载产品的 COA,每批产品都进行了严格的验证,您可放心使用!
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
| 分析证书 | Ab104034 | |
| 分析证书 | Ab104034 | |
| 分析证书 | Ab104034 |
| 1. Zhang, Q H QH and 20 more authors.. (2000) Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.. Genome research, [PMID:11042152] |
| 2. Banham, A H AH and 11 more authors.. (2001) The FOXP1 winged helix transcription factor is a novel candidate tumor suppressor gene on chromosome 3p.. Cancer research, (15): [PMID:11751404] |
| 3. Shi, Can C and 7 more authors.. (2004) Integrin engagement regulates monocyte differentiation through the forkhead transcription factor Foxp1.. The Journal of clinical investigation, [PMID:15286807] |
| 4. Muzny, Donna M DM and 113 more authors.. (2006) The DNA sequence, annotation and analysis of human chromosome 3.. Nature, (27): [PMID:16641997] |
| 5. Mullighan, Charles G CG and 15 more authors.. (2007) Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia.. Nature, (12): [PMID:17344859] |
| 6. Jepsen, Kristen K, Gleiberman, Anatoli S AS, Shi, Can C, Simon, Daniel I DI and Rosenfeld, Michael G MG.. (2008) Cooperative regulation in development by SMRT and FOXP1.. Genes & development, (15): [PMID:18347093] |
| 7. Takayama, Kenichi K and 7 more authors.. (2008) FOXP1 is an androgen-responsive transcription factor that negatively regulates androgen receptor signaling in prostate cancer cells.. Biochemical and biophysical research communications, (19): [PMID:18640093] |
| 8. Shi, Can C and 10 more authors.. (2008) Down-regulation of the forkhead transcription factor Foxp1 is required for monocyte differentiation and macrophage function.. Blood, (1): [PMID:18799727] |
| 9. Vernes, Sonja C SC, MacDermot, Kay D KD, Monaco, Anthony P AP and Fisher, Simon E SE.. (2009) Assessing the impact of FOXP1 mutations on developmental verbal dyspraxia.. European journal of human genetics : EJHG, [PMID:19352412] |
| 10. Horn, Denise D and 22 more authors.. (2010) Identification of FOXP1 deletions in three unrelated patients with mental retardation and significant speech and language deficits.. Human mutation, [PMID:20848658] |
| 11. Hamdan, Fadi F FF and 18 more authors.. (2010) De novo mutations in FOXP1 in cases with intellectual disability, autism, and language impairment.. American journal of human genetics, (12): [PMID:20950788] |
| 12. Chu, Yuan-Ping YP and 5 more authors.. (2011) Solution structure and backbone dynamics of the DNA-binding domain of FOXP1: insight into its domain swapping and DNA binding.. Protein science : a publication of the Protein Society, [PMID:21416545] |
| 13. Gabut, Mathieu M and 17 more authors.. (2011) An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming.. Cell, (30): [PMID:21924763] |
| 14. Zhou, Houjiang H and 6 more authors.. (2013) Toward a comprehensive characterization of a human cancer cell phosphoproteome.. Journal of proteome research, (4): [PMID:23186163] |
| 15. Grundmann, Sebastian S and 8 more authors.. (2013) FoxP1 stimulates angiogenesis by repressing the inhibitory guidance protein semaphorin 5B in endothelial cells.. PloS one, [PMID:24023716] |
| 16. Sin, Cora C, Li, Hongyan H and Crawford, Dorota A DA.. (2015) Transcriptional regulation by FOXP1, FOXP2, and FOXP4 dimerization.. Journal of molecular neuroscience : MN, [PMID:25027557] |
| 17. van Keimpema, Martine M and 7 more authors.. (2014) FOXP1 directly represses transcription of proapoptotic genes and cooperates with NF-κB to promote survival of human B cells.. Blood, (27): [PMID:25267198] |
| 18. Sollis, Elliot E and 11 more authors.. (2016) Identification and functional characterization of de novo FOXP1 variants provides novel insights into the etiology of neurodevelopmental disorder.. Human molecular genetics, (1): [PMID:26647308] |
| 19. Kamran, M M and 8 more authors.. (2017) Aurora kinase A regulates Survivin stability through targeting FBXL7 in gastric cancer drug resistance and prognosis.. Oncogenesis, (20): [PMID:28218735] |
| 20. Eising, Else E and 15 more authors.. (2019) A set of regulatory genes co-expressed in embryonic human brain is implicated in disrupted speech development.. Molecular psychiatry, [PMID:29463886] |
| 21. den Hoed, Joery J and 5 more authors.. (2018) Functional characterization of TBR1 variants in neurodevelopmental disorder.. Scientific reports, (24): [PMID:30250039] |
| 22. Connaughton, Dervla M and 98 more authors.. (2020) Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations.. American journal of human genetics, (1): [PMID:32891193] |