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FOXP1 Mouse mAb

    应用:
  • WB
  • 宿主种属: 小鼠(Mouse)
  • 种属反应性: 人(Human), 小鼠(Mouse)
  • 亚型: Mouse IgG2a
  • 克隆号: D4
  • 偶联: Unconjugated
有货

库存信息

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库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
Ab104034-10μl
10μl 现货 Stock Image
Ab104034-50μl
50μL 现货 Stock Image
Ab104034-100μl
100μL 现货 Stock Image
Ab104034-1ml
1ml 期货 Stock Image

基本信息

产品名称 FOXP1 Mouse mAb
别名 叉头框蛋白P1单克隆抗体 | 抗FOXP1抗体
英文别名 12CC4 antibody | FLJ23741 antibody | Fork head related protein like B antibody | Forkhead box P1 antibody | Forkhead box protein P1 antibody | FOX P1 antibody | FOXP 1 antibody | foxp1 antibody | FOXP1_HUMAN antibody | Glutamine rich factor 1 antibody | h
规格或纯度 无载体, ExactAb™, 无叠氮钠, 已验证, 见COA
宿主种属 小鼠(Mouse)
特异性 FOXP1
种属反应性 人(Human),小鼠(Mouse)
免疫原 Recombinant FOXP1 expressed in E.coli (AA 461-671)
阳性对照 WB: RAW264.7, MCF7 and Raji cell lysates.
偶联 Unconjugated

产品属性

克隆类型 单克隆抗体
克隆号 D4
Format Whole IgG
亚型 Mouse IgG2a
轻链亚型 kappa
SDS-PAGE 150 kDa
纯化方法 Protein A and Protein G purified
物理外观 Liquid
储存缓冲液 10mM PBS, 50% Glycerol, 0.05% Proclin 300, pH7.4
防腐剂 0.05% Proclin 300
浓度 见COA
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 4℃ 短期储存(1-2 周)。-20℃长期保存(24 个月)。收货后建议分装。避免冷冻/解冻循环。
分子类型 抗体

关联靶点(人)

FOXP1 Tbio 叉头框蛋白P1(Forkhead box protein P1) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
PCGF1 Tbio 多梳组环指蛋白1(Polycomb group RING finger protein 1) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)

图片

FOXP1 Mouse mAb (Ab104034) - Western Blot
All lanes: FOXP1 Mouse mAb (Ab104034) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab138040) at 1/50000 dilution

Predicted band size: 75 kDa
Observed band size: 80 kDa
Exposure time: 200.0 s


应用

应用名称 稀释比例
WB

0.5-2 µg/mL

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA,每批产品都进行了严格的验证,您可放心使用!

找到3个结果

批号(Lot Number) 证书类型 货号
ZJ23F1001485 分析证书 Ab104034
ZJ24F1011845 分析证书 Ab104034
ZJ23F1001486 分析证书 Ab104034

技术文档和文章

石蜡样品的免疫组化染色方案(IHC-P)
蛋白质印迹的一抗选择指南
Guidelines of Primary Antibodies for Western Blotting
Guidelines of Primary Antibodies for Western Blotting
高分子量蛋白质印迹法
Protocol of Western Blotting For High Molecular Weights
Protocol of Western Blotting For High Molecular Weights
Protocol of Western Blotting For High Molecular Weights
Protocol of Western Blotting For High Molecular Weights

引用文献

1. Zhang, Q H QH and 20 more authors..  (2000)  Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells..  Genome research,  [PMID:11042152]
2. Banham, A H AH and 11 more authors..  (2001)  The FOXP1 winged helix transcription factor is a novel candidate tumor suppressor gene on chromosome 3p..  Cancer research,  (15): [PMID:11751404]
3. Shi, Can C and 7 more authors..  (2004)  Integrin engagement regulates monocyte differentiation through the forkhead transcription factor Foxp1..  The Journal of clinical investigation,  [PMID:15286807]
4. Muzny, Donna M DM and 113 more authors..  (2006)  The DNA sequence, annotation and analysis of human chromosome 3..  Nature,  (27): [PMID:16641997]
5. Mullighan, Charles G CG and 15 more authors..  (2007)  Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia..  Nature,  (12): [PMID:17344859]
6. Jepsen, Kristen K, Gleiberman, Anatoli S AS, Shi, Can C, Simon, Daniel I DI and Rosenfeld, Michael G MG..  (2008)  Cooperative regulation in development by SMRT and FOXP1..  Genes & development,  (15): [PMID:18347093]
7. Takayama, Kenichi K and 7 more authors..  (2008)  FOXP1 is an androgen-responsive transcription factor that negatively regulates androgen receptor signaling in prostate cancer cells..  Biochemical and biophysical research communications,  (19): [PMID:18640093]
8. Shi, Can C and 10 more authors..  (2008)  Down-regulation of the forkhead transcription factor Foxp1 is required for monocyte differentiation and macrophage function..  Blood,  (1): [PMID:18799727]
9. Vernes, Sonja C SC, MacDermot, Kay D KD, Monaco, Anthony P AP and Fisher, Simon E SE..  (2009)  Assessing the impact of FOXP1 mutations on developmental verbal dyspraxia..  European journal of human genetics : EJHG,  [PMID:19352412]
10. Horn, Denise D and 22 more authors..  (2010)  Identification of FOXP1 deletions in three unrelated patients with mental retardation and significant speech and language deficits..  Human mutation,  [PMID:20848658]
11. Hamdan, Fadi F FF and 18 more authors..  (2010)  De novo mutations in FOXP1 in cases with intellectual disability, autism, and language impairment..  American journal of human genetics,  (12): [PMID:20950788]
12. Chu, Yuan-Ping YP and 5 more authors..  (2011)  Solution structure and backbone dynamics of the DNA-binding domain of FOXP1: insight into its domain swapping and DNA binding..  Protein science : a publication of the Protein Society,  [PMID:21416545]
13. Gabut, Mathieu M and 17 more authors..  (2011)  An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming..  Cell,  (30): [PMID:21924763]
14. Zhou, Houjiang H and 6 more authors..  (2013)  Toward a comprehensive characterization of a human cancer cell phosphoproteome..  Journal of proteome research,  (4): [PMID:23186163]
15. Grundmann, Sebastian S and 8 more authors..  (2013)  FoxP1 stimulates angiogenesis by repressing the inhibitory guidance protein semaphorin 5B in endothelial cells..  PloS one,  [PMID:24023716]
16. Sin, Cora C, Li, Hongyan H and Crawford, Dorota A DA..  (2015)  Transcriptional regulation by FOXP1, FOXP2, and FOXP4 dimerization..  Journal of molecular neuroscience : MN,  [PMID:25027557]
17. van Keimpema, Martine M and 7 more authors..  (2014)  FOXP1 directly represses transcription of proapoptotic genes and cooperates with NF-κB to promote survival of human B cells..  Blood,  (27): [PMID:25267198]
18. Sollis, Elliot E and 11 more authors..  (2016)  Identification and functional characterization of de novo FOXP1 variants provides novel insights into the etiology of neurodevelopmental disorder..  Human molecular genetics,  (1): [PMID:26647308]
19. Kamran, M M and 8 more authors..  (2017)  Aurora kinase A regulates Survivin stability through targeting FBXL7 in gastric cancer drug resistance and prognosis..  Oncogenesis,  (20): [PMID:28218735]
20. Eising, Else E and 15 more authors..  (2019)  A set of regulatory genes co-expressed in embryonic human brain is implicated in disrupted speech development..  Molecular psychiatry,  [PMID:29463886]
21. den Hoed, Joery J and 5 more authors..  (2018)  Functional characterization of TBR1 variants in neurodevelopmental disorder..  Scientific reports,  (24): [PMID:30250039]
22. Connaughton, Dervla M and 98 more authors..  (2020)  Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations..  American journal of human genetics,  (1): [PMID:32891193]

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