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Hematologica Malignancies CAR Targets
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Recombinant Bovine CD4 ProteinSpecies: Bovine Accession #: F1MJK4Expression system: HEK293 Protein Tag: C-His Endotoxin Concentration: <1.0 EU/μgBioactivity: Measured by the ability of the immobilized protein to support the adhesion of NIH‑3T3 mouse embryonic fibroblast cells.The ED50for this effect is 0.1-0.5 μg/mL after a 1 hour incubation at37 °C.Optimal dilutions should be determined by each laboratory for each application.Synonyms: T-cell surface glycoprotein CD4 | T-cell surface antigen T4/Leu-3 | CD4
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Recombinant Human PD-L1 ProteinSpecies: Human Accession #: Q9NZQ7Expression system: HEK293 Protein Tag: C-His Endotoxin Concentration: <1.0 EU/μgBioactivity: Immobilized Recombinant Human PD-L1 Protein (rp169666) at 2.0 μg/mL can bind Sugemalimab (anti-PD-L1) (Ab175662) with the EC50 of 169.70 ng/mL. Immobilized Recombinant Human PD-L1 Protein (rp169666) at 1.0 μg/mL can bind Avelumab (anti-PD-L1) (A412006) with the EC50 of 77.96 ng/mL. Immobilized Recombinant Human PD-L1 Protein (rp169666) at 1.0 μg/mL can bind Envafolimab (anti-PD-L1) (Ab170617) with the EC50 of 339.40 ng/mL. Immobilized Recombinant Human PD-L1 Protein (rp169666) at 1.0 μg/mL can bind Durvalumab (anti-PD-L1) (D412005) with the EC50 of 35.40 ng/mL.Synonyms: B7 H | B7 H1 | B7 homolog 1 | B7-H1 | B7H | B7H1 | CD 274 | CD-274 | CD274 | CD274 antigen | CD274 molecule | MGC1422...
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Recombinant Human Siglec-3/CD33 ProteinSpecies: Human Accession #: P20138Expression system: HEK293 Protein Tag: C-His Endotoxin Concentration: <1.0 EU/μgBioactivity: 1. Measured by the ability of the immobilized protein to support the adhesion of human red blood cells. The ED50 for this effect is < 6 µg/mL. 2. Immobilized Recombinant Human Siglec-3/CD33 Protein (rp169578) at 1.0 μg/mL can bind Vadastuximab (anti-CD33) (Ab182778) with the EC50 of 10.59 ng/mL. 3. Immobilized Recombinant Human Siglec-3/CD33 Protein (rp169578) at 1.0 μg/mL can bind Gemtuzumab (anti-CD33) (Ab175859) with the EC50 of 36.93 ng/mL.Synonyms: CD33 antigen (gp67) | CD33 antigen | CD33 molecule | CD33 | FLJ00391 | gp67 | myeloid cell surface antigen CD33 | p67...
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Recombinant Human Siglec-2/CD22 ProteinSpecies: Human Accession #: P20273Expression system: HEK293 Protein Tag: C-His Endotoxin Concentration: <1.0 EU/μgBioactivity: Immobilized Recombinant Human Siglec-2/CD22 Protein (rp169575) at 1.0 μg/mL can bind Inotuzumab (anti-CD22) (Ab176429) with the EC50 of 20.1 ng/mL. Immobilized Recombinant Human Siglec-2/CD22 Protein (rp169575) at 1.0 μg/mL can bind bind Epratuzumab (anti-CD22) (Ab175532) with the EC50 of 207.0 ng/mL.Synonyms: B-cell receptor CD22 | BL-CAM | B-lymphocyte cell adhesion molecule | CD22 antigenMGC130020 | CD22 molecule | CD22 | ...
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Recombinant Human BCMA/TNFRSF17 ProteinSpecies: Human Accession #: Q6PE46Expression system: HEK293 Protein Tag: C-hFc Endotoxin Concentration: <1.0 EU/μgBioactivity: Immobilized Recombinant Human BCMA/TNFRSF17 Protein (rp169554) at 0.5 μg/mL can bind Belantamab (anti-TNFRSF17) (Ab170526) with the EC50 of 22.0 ng/mL.Synonyms: B cell maturation antigen | B-cell maturation protein | BCMA | BCMAtumor necrosis factor receptor superfamily member ...
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Recombinant Human CD72 ProteinSpecies: Human Accession #: P21854Expression system: HEK293 Protein Tag: C-His Endotoxin Concentration: <1.0 EU/μgBioactivity: Testing in progressSynonyms: CD72 antigen | B-cell differentiation antigen CD72 | B cell differentiation antigen CD72 | CD72 molecule | CD72_HUMAN...
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Recombinant Feline CD19 ProteinSpecies: Feline Accession #: M3VZQ6Expression system: E. coli Protein Tag: C-HisSynonyms: B-lymphocyte antigen CD19 | B-lymphocyte surface antigen B4 | CD19 antigen | CD19 molecule | CD19 | CVID3 | Different...
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Recombinant Human CD30/TNFRSF8 ProteinSpecies: Human Accession #: P28908Expression system: HEK293 Protein Tag: C-His Endotoxin Concentration: <1.0 EU/μgBioactivity: Immobilized Recombinant Human CD30 Protein (rp169577) at 1.0 μg/mL can bind Brentuximab (anti-TNFRSF8) (Ab170548) with the EC50 of 119.9 ng/mL.Synonyms: CD30 | CD30KI-1 | CD30L receptor | cytokine receptor CD30 | D1S166EKi-1 | Ki-1 antigen | Lymphocyte activation antige...
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Recombinant Human CD5 ProteinSpecies: Human Accession #: P06127Expression system: HEK293 Protein Tag: C-His Endotoxin Concentration: <1.0 EU/μgBioactivity: Immobilized Recombinant Human CD5 Protein (rp176727) at 1.0 μg/mL can bind CD5 Mouse mAb (Ab006673) with the EC50 of 11.62 ng/mL.Synonyms: CD5 antigen | CD5 antigen (p56-62) | CD5 molecule | CD5 | LEU1T-cell surface glycoprotein CD5 | Lymphocyte antigen T1...
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Recombinant Human CD38 ProteinSpecies: Human Accession #: P28907Expression system: HEK293 Protein Tag: C-His Endotoxin Concentration: <1.0 EU/μgBioactivity: Immobilized Recombinant Human CD38 Protein (rp176716) at 2.0 μg/mL can bind CD38 Mouse mAb (Ab094687) with the EC50 of 37.67 ng/mL.Synonyms: T10 | p45 | OTTHUMP00000217743 | OTTHUMP00000158633 | NIMR5 antigen (mouse) | NIM-R5 antigen | NAD(+) nucleosidase | ...
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Recombinant Human CD7 ProteinSpecies: Human Accession #: P09564Expression system: HEK293 Protein Tag: C-His Endotoxin Concentration: <1.0 EU/μgBioactivity: Immobilized Recombinant Human CD7 protein (rp176728) at 1.0 μg/mL can bind CD7 Mouse mAb (Ab095225) with the EC50 of 53.82 ng/mL.Synonyms: CD7 antigen | CD7 | CD7 antigen (p41) | CD7 molecule | CD7_HUMAN | GP40 | LEU 9 | LEU9 | p41 protein | T cell antigen...
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Recombinant Human SLAMF7/CRACC ProteinSpecies: Human Accession #: Q9NQ25-1Expression system: HEK293 Protein Tag: C-His Endotoxin Concentration: <1.0 EU/μgBioactivity: Testing in progressSynonyms: 19A | CD2 subset 1 | CD2-like receptor activating cytotoxic cells | CD319 antigen | CD319 | CRACC | CRACCCD2-like rec...
