This is a demo store. No orders will be fulfilled.

Recombinant Human CD7 Protein

  • Expression System: HEK293
  • Accession #: P09564
  • Protein Tag: C-His
  • Bioactivity: Immobilized Recombinant Human CD7 protein (rp176728) at 1.0 μg/mL can bind CD7 Mouse mAb (Ab095225) with the EC50 of 53.82 ng/mL.
  • Endotoxin Concentration: <1.0 EU/μg
In stock
Item Number
rp176728
Grouped product items
SKU Size
Availability
Price Qty
rp176728-10μg
10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$89.90
rp176728-50μg
50μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$269.90
rp176728-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$429.90
rp176728-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,569.90

Animal Free, ≥95% (SDS-PAGE), Active, 293F cell, C-His tag, 1-180 aa

Basic Description

Product Name Recombinant Human CD7 Protein
Synonyms CD7 antigen | CD7 | CD7 antigen (p41) | CD7 molecule | CD7_HUMAN | GP40 | LEU 9 | LEU9 | p41 protein | T cell antigen CD7 | T cell leukemia antigen | T cell surface antigen Leu 9 | T-cell antigen CD7 | T-cell leukemia antigen | T-cell surface antigen Leu-
Grade ActiBioPure™, Animal Free, Bioactive, Carrier Free
Product Description

CD7, also known as Leu-9, is an approximately 40 kDa glycosylated and palmitoylated transmembrane protein in the immunoglobulin superfamily. Mature human CD7 consists of a 155 amino acid (aa) extracellular domain (ECD), a 21 aa transmembrane segment, and a 39 aa cytoplasmic domain. Within the ECD, human CD7 shares 43% and 41% aa sequence identity with mouse and rat CD7, respectively. CD7 is expressed on T cells, NK cells, myeloid progenitor cells, and CD19+ B progenitor cells. Among CD8+ T cells, the CD7-bright population preferentially contains naïve and memory cells, while more weak expressors are primarily effector cells. CD7 associates in cis with CD3 and CD45 and in trans with SECTM1. Ligation of CD7 with antibodies or SECTM1 co‑stimulates the activation and proliferation of CD4+ and CD8+ T cells and NK cells. It also enhances integrin-mediated adhesion of these cells to Fibronectin, ICAM-1, and VCAM-1. CD7 additionally mediates the Galectin-1 induced apoptosis of T cells and facilitates the fusion of HIV-1 with target cells.

Specifications & Purity ActiBioPure™, Bioactive, Animal Free, Carrier Free, ≥95%(SDS-PAGE)
Bioactivity Immobilized Recombinant Human CD7 protein (rp176728) at 1.0 μg/mL can bind CD7 Mouse mAb (Ab095225) with the EC50 of 53.82 ng/mL.
Endotoxin Concentration <1.0 EU/μg
Expression System HEK293
Amino Acids 1-180 aa
Sequence MAGPPRLLLLPLLLALARGLPGALAAQEVQQSPHCTTVPVGASVNITCSTSGGLRGIYLRQLGPQPQDIIYYEDGVVPTTDRRFRGRIDFSGSQDNLTITMHRLQLSDTGTYTCQAITEVNVYGSGTLVLVTEEQSQGWHRCSDAPPRASALPAPPTGSALPDPQTASALPDPPAASALPHHHHHH
Protein Tag C-His
Accession # P09564
Predicted molecular weight 16.4 kDa
SDS-PAGE 22.3-39.5 kDa, under reducing conditions; 22.8-38.0 & 21.7 kDa, under non-reducing conditions

Storage and Shipping

Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -20°C for 1 year. Avoid freeze / thaw cycle.

Images

Recombinant Human CD7 Protein (rp176728) - ELISA
Immobilized Recombinant Human CD7 Protein (rp176728) at 1.0 μg/mL can bind CD7 Mouse mAb (Ab095225) with the EC50 of 53.82 ng/mL.

Recombinant Human CD7 Protein (rp176728) - SDS-PAGE
3 μg/lane of Recombinant Human CD7 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 22.3-39.5 kDa under reducing conditions and 22.8-38.0 & 21.7 kDa under non-reducing conditions.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

1 results found

Lot Number Certificate Type Date Item
ZJ24R0800865 Certificate of Analysis Aug 02, 2024 rp176728

Solution Calculators

Reviews

Customer Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.