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Recombinant JNK2 Antibody - Primary antibody, specific to JNK2, Rabbit IgG

COA COA
    Application:
  • IHC
  • WB
  • Host species: Rabbit
  • Reactive species: Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab111533
Grouped product items
SKU Size
Availability
 Price Qty
Ab111533-10μl
10μl
5
$66.90
Ab111533-50μl
50μl
2
$199.90
Ab111533-100μl
100μl
1
$299.90
Ab111533-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,299.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Recombinant; Rabbit anti Human JNK2 Antibody; WB, IHC; Unconjugated

View related series
Click to view target information: MAPK9
Accession#:P45984 (2) Gene ID:5601 (2) JNK2 (2) MAPK9 (2)

Basic Description

Product Name Recombinant JNK2 Antibody - Primary antibody, specific to JNK2, Rabbit IgG
Synonyms c Jun kinase 2 antibody | C Jun N terminal kinase 2 antibody | c-Jun N-terminal kinase 2 antibody | JNK 55 antibody | JNK-55 antibody | JNK2 alpha antibody | JNK2 antibody | JNK2 beta antibody | JNK2A antibody | JNK2alpha antibody | JNK2B antibody | JNK2B
Specifications & Purity ExactAb™, Validated, Recombinant, 0.3 mg/mL
Host species Rabbit
Specificity JNK2
Immunogen A synthetic peptide derived from human JNK2 (AA 361-374).
Positive Control WB: K562, HEK293, C6 and NIH/3T3 cell lysates. IHC: Human colon cancer tissue.
Conjugation Unconjugated
Grade ExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human JNK2 Antibody, Recombinant, could be used for WB, IHC and so on.
Application:
WB: 1/500-1/1000
IHC: 1/50-1/100
Function
Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells. JNK2 isoforms display different binding patterns: alpha-1 and alpha-2 preferentially bind to c-Jun, whereas beta-1 and beta-2 bind to ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms. JUNB is not a substrate for JNK2 alpha-2, and JUND binds only weakly to it.

Product Properties

Isotype Rabbit IgG
SDS-PAGE 150 kDa
Purification Method Antigen affinity purified
Shape Liquid
Concentration 0.3 mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

MAPK9 Tchem Mitogen-activated protein kinase 9 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Recombinant JNK2 Antibody (Ab111533) - Western Blot
All lanes: Recombinant JNK2 Antibody (Ab111533) at 1/2000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 48 kDa
Observed band size: 41, 49 kDa
Exposure time: 6.4 s

Recombinant JNK2 Antibody (Ab111533) - IHC
Immunohistochemistry analysis of paraffin-embedded Human colon cancer using Recombinant JNK2 Antibody (Ab111533). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Application

Application Dilution info
WB

1/500-1/1000
IHC

1/50 - 1/100

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F1001241 Certificate of Analysis Oct 10, 2023 Ab111533
ZJ23F1001240 Certificate of Analysis Oct 10, 2023 Ab111533

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