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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab191916-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$109.90
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Ab191916-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$519.90
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Ab191916-5mg
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5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,299.90
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Ab191916-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,079.90
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Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated
| Product Name | APX-007 (anti-IL-6Ra) - Primary antibody, specific to IL6R, Human IgG1 |
|---|---|
| Synonyms | CD 126 antibody | CD126 antibody | CD126 antigen antibody | gp80 antibody | IL 6R 1 antibody | IL 6R alpha antibody | IL 6R antibody | IL-6 receptor alpha chain antibody | IL-6 receptor subunit alpha antibody | IL-6R 1 antibody | IL-6R subunit alpha antib |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Biochemical and Physiological Mechanisms | Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hemat |
| Host species | Human |
| Specificity | IL6R |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
APX-007 (anti-IL-6Ra) is a monoclonal antibody targeting IL-6R/CD126. It can be used in the pathogenesis of multiple myeloma. |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A purified |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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APX-007 (anti-IL-6Ra) (Ab191916) - ELISA
Immobilized Recombinant Human IL-6Ra protein at 1.0 μg/mL can bind APX-007 (anti-IL-6Ra) (Ab191916) with the EC₅₀ of 58.73 ng/mL.
APX-007 (anti-IL-6Ra) (Ab191916) - SEC
The purity of APX-007 (anti-IL-6Ra) (Ab191916) is more than 95% verified by HPLC.
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Starting at $39.90