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APX-007 (anti-IL-6Ra) - Primary antibody, specific to IL6R, Human IgG1

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab191916
Grouped product items
SKU Size
Availability
Price Qty
Ab191916-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$109.90
Ab191916-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$519.90
Ab191916-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,299.90
Ab191916-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,079.90

Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name APX-007 (anti-IL-6Ra) - Primary antibody, specific to IL6R, Human IgG1
Synonyms CD 126 antibody | CD126 antibody | CD126 antigen antibody | gp80 antibody | IL 6R 1 antibody | IL 6R alpha antibody | IL 6R antibody | IL-6 receptor alpha chain antibody | IL-6 receptor subunit alpha antibody | IL-6R 1 antibody | IL-6R subunit alpha antib
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Biochemical and Physiological Mechanisms Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hemat
Host species Human
Specificity IL6R
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

APX-007 (anti-IL-6Ra) is a monoclonal antibody targeting IL-6R/CD126. It can be used in the pathogenesis of multiple myeloma.

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein A purified
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

IL6R Tclin Interleukin-6 receptor subunit alpha (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
IL6R Tclin Interleukin-6 receptor alpha subunit (0 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

APX-007 (anti-IL-6Ra) (Ab191916) - ELISA
Immobilized Recombinant Human IL-6Ra protein at 1.0 μg/mL can bind APX-007 (anti-IL-6Ra) (Ab191916) with the EC₅₀ of 58.73 ng/mL.

APX-007 (anti-IL-6Ra) (Ab191916) - SEC
The purity of APX-007 (anti-IL-6Ra) (Ab191916) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

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