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ANGPT2 Antibody - Primary antibody, specific to ANGPT2, Rabbit IgG

    Application:
  • IHC
  • WB
  • Host species: Rabbit
  • Reactive species: Human,Mouse
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab088801
Grouped product items
SKU Size
Availability
Price Qty
Ab088801-20μl
20μl
5
$89.90
Ab088801-10μl
10μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$59.90
Ab088801-50μl
50μl
9
$180.90
Ab088801-100μl
100μl
4
$279.90
Ab088801-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,007.90

pAb; Rabbit anti Human ANGPT2 Antibody; WB, IHC; Unconjugated

Basic Description

Product Name ANGPT2 Antibody - Primary antibody, specific to ANGPT2, Rabbit IgG
Synonyms AGPT 2 antibody | Agpt2 antibody | ANG 2 antibody | ANG-2 antibody | ANG2 antibody | Angiopoietin 2a antibody | Angiopoietin 2B antibody | Angiopoietin-2 antibody | Angiopoietin2 antibody | ANGP2_HUMAN antibody | ANGPT 2 antibody | Angpt2 antibody | Tie2
Specifications & Purity Carrier Free, ExactAb™, Azide Free, Validated, High Performance, See COA
Host species Rabbit
Specificity ANGPT2
Immunogen Recombinant ANGPT2 expressed in E.coli (AA 24-165)
Positive Control WB: K562 and HUVEC cell lysates. IHC: Human Placenta Tissue
Conjugation Unconjugated
Grade Azide Free, Carrier Free, ExactAb™, High Performance, Validated
Product Description

Rabbit anti Human ANGPT2 Antibody, Polyclonal antibody, could be used for WB, IHC and so on.
Application
WB: 0.2-2µg/mL
IHC: 5-20µg/mL
Protein Function
Can induce tyrosine phosphorylation of TIE2. Binds to TIE2 receptor and counteracts blood vessel maturation/stability mediated by angiopoietin-1. Its function may be context-dependent. In the absence of angiogenic inducers, such as VEGF, ANG2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.

Product Properties

Isotype Rabbit IgG
SDS-PAGE 150 kDa
Purification Method Antigen-specific affinity chromatography followed by Protein A affinity chromatography.
Shape Liquid
Concentration See COA
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

ANGPT2 Tclin Angiopoietin-2 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

ANGPT2 Antibody (Ab088801) - Western Blot
All lanes: ANGPT2 Antibody (Ab088801) at 1/5000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/30000 dilution

Predicted band size: 79 kDa
Observed band size: 73 kDa
Exposure time: 0.8 s

ANGPT2 Antibody (Ab088801) - IHC
DAB staining on IHC
Samples: Human Placenta Tissue
Primary Ab: 20 μg/mL ANGPT2 Antibody (Ab088801)
Second Ab: 2 µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.

Application

Application Dilution info
IHC

5-20 µg/mL

WB

0.2-2 µg/mL

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ23F1202111 Certificate of Analysis Dec 20, 2023 Ab088801
ZJ23F1202110 Certificate of Analysis Dec 20, 2023 Ab088801
ZJ23F1202109 Certificate of Analysis Dec 20, 2023 Ab088801

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