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代谢疾病靶点
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Recombinant Mouse Leptin ProteinCAS号: 181030-10-4分子式: NA种属: 小鼠(Mouse) Accession #: Q544U0表达系统: E. coli 蛋白标签: No tag 内毒素水平: <1.0 EU/μg生物活性: Immobilized Recombinant Mouse LEPR (C-10His) at 5μg/ml (100 μl/well) can bind Recombinant Mouse Leptin Biotinylated by NHS-biotin prior to testing.The ED50 of Recombinant Mouse Leptin is 1.16 ng/ml. Loaded Recombinant Mouse LEPR (C-10His) on HIS1K Biosensor, can bind Recombinant Mouse Leptin with an affinity constant of 0.196 nM as determined in BLI assay.
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Recombinant Mouse TNF-alpha Protein种属: 小鼠(Mouse) Accession #: P06804表达系统: E. coli 蛋白标签: No tag 内毒素水平: <0.01 EU/μg生物活性: Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D (Catalog # A113142). The ED₅₀ for this effect is typically <0.1 ng/mL.
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Recombinant Mouse IL-2 Protein种属: 小鼠(Mouse) Accession #: P04351表达系统: HEK293 蛋白标签: N-His 内毒素水平: <1.0 EU/μg生物活性: Recombinant Mouse IL-2 stimulates cell proliferation of the CTLL-2 mouse cytotoxic T cell line. The ED50 for this effect is typically less than 2.5 ng/mL.
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Recombinant Mouse TRANCE/RANKL/TNFSF11 Protein种属: 小鼠(Mouse) Accession #: O35235表达系统: HEK293 蛋白标签: N-Met & Fc 内毒素水平: <0.01 EU/μg生物活性: Measured by its ability to induce TRAP activity in Raw 264.7 cells.The ED50 of each lot is between 2-10 ng/mL.
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Recombinant Mouse FGF-21 Protein种属: 小鼠(Mouse) Accession #: Q9JJN1表达系统: E. coli 蛋白标签: No tag 内毒素水平: <0.1 EU/μg生物活性: Fully biologically active when compared to standard. The ED₅₀ as determined by thymidine uptake assay using FGF-receptors transfected BaF3 cells is less than 0.5 μg/ml, corresponding to a specific activity of >2.0 ×10³IU/mg in the presence of 5 µg/ml of rMuβ-Klotho and 10 μg/ml of heparin.
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Recombinant Mouse IL-10 Protein种属: 小鼠(Mouse) Accession #: P18893表达系统: HEK293 蛋白标签: C-His 内毒素水平: <0.1 EU/μg生物活性: Measured in a cell proliferation assay using MC/9‑2 mouse mast cells. The ED₅₀ for this effect is 0.8 ng/mL.
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Recombinant Mouse TNF-alpha Protein种属: 小鼠(Mouse) Accession #: P06804表达系统: HEK293 蛋白标签: No tag 内毒素水平: <0.1 EU/μg生物活性: Recombinant Mouse TNF-alpha induces cytotoxicity in the L-929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is typically 29-116 pg/mL, corresponding to a specific activity of 8.62×10^6-3.45×10^7 units/mg.
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Recombinant Mouse TGF-beta 1 Protein种属: 小鼠(Mouse) Accession #: P04202表达系统: HEK293 蛋白标签: N-8His 内毒素水平: <0.1 EU/μg生物活性: Recombinant Mouse TGF-beta 1 inhibits the IL-4-dependent proliferation of HT-2 mouse T cells. The ED50 for this effect is 0.02-0.1 ng/ml.
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Recombinant Mouse OX40 Ligand/TNFSF4 Protein种属: 小鼠(Mouse) Accession #: P43488表达系统: HEK293 蛋白标签: N-10His 内毒素水平: <0.1 EU/μg生物活性: Measured by its ability to co-stimulate IL-2 secretion by mouse T cells in the presence of anti-CD3. The ED50 for this effect is 10-30 ng/mL in the presence of a cross-linking antibody, Mouse Anti-polyHistidine Monoclonal Antibody.
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Recombinant Mouse gp130 Protein种属: 小鼠(Mouse) Accession #: Q6PDI9表达系统: HEK293 蛋白标签: C-His 内毒素水平: <0.1 EU/μg生物活性: Measured by its ability to inhibit IL-6-dependent proliferation of the 7TD1 mouse hybridoma cells in the presence of Recombinant Human IL-6 R alpha. The ED50 for this effect is 1.8 ng/mL.
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Recombinant Mouse CD25/IL-2R alpha Protein种属: 小鼠(Mouse) Accession #: Q544I2表达系统: HEK293 蛋白标签: C-10His 内毒素水平: <0.1 EU/μg生物活性: Measured by its ability to inhibit the IL-2-dependent proliferation of MO7e human megakaryocytic leukemic cells. The ED50 for this effect is 0.045-0.3 µg/mL in the presence of 30 ng/mL of recombinant human IL-2.
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Recombinant Mouse Leptin R Protein种属: 小鼠(Mouse) Accession #: P48356表达系统: HEK293 蛋白标签: C-His 内毒素水平: <0.1 EU/μg生物活性: Measured by its ability to inhibit Leptin-dependent proliferation of BaF3 mouse pro‑B cells transfected with human Leptin R. The ED50 for this effect is 2-10 ng/mL in the presence of 1 ng/mL recombinant mouse Leptin.
