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免疫疾病靶点

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  1. Recombinant Human IL-6R Protein
      种属: 人(Human)    Accession #: P08887    
      表达系统: HEK293    蛋白标签: C-His    内毒素水平: <1.0 EU/μg    
      生物活性: 1. Immobilized Recombinant Human IL-6 Protein at 2 μg/mL can bind Recombinant Human IL-6R Protein (rp147628) the EC50 is 8.0 - 24.0 ng/mL. 2. Measured by its ability to enhance the IL-6 activity on M1 mouse myeloid leukemia cells. The ED50 for this effect is typically 10.0 - 60.0 ng/mL.3. Using the Octet RED System, the affinity constant (Kd) of Recombinant Human IL-6R Protein (rp147628) bound Anti-IL6R Antibody was 0.1 nM.    
  2. Recombinant Bovine CD4 Protein
      种属: 牛(Bovine)    Accession #: F1MJK4    
      表达系统: HEK293    蛋白标签: C-His    内毒素水平: <1.0 EU/μg    
      生物活性: Measured by the ability of the immobilized protein to support the adhesion of NIH‑3T3 mouse embryonic fibroblast cells.The ED50for this effect is 0.1-0.5 μg/mL after a 1 hour incubation at37 °C.Optimal dilutions should be determined by each laboratory for each application.    
  3. Recombinant Human CD79B Protein
      种属: 人(Human)    Accession #: P40259    
      表达系统: HEK293    蛋白标签: C-His    内毒素水平: <1.0 EU/μg    
      生物活性: 1. Immobilized Recombinant Human CD79B Protein (rp176729) at 1.0 μg/mL can bind Polatuzumab (anti-CD79b) (Ab175715) with the EC50 of 11.08 ng/mL. 2. Immobilized Recombinant Human CD79B Protein (rp176729) at 1.0 μg/mL can bind Polatuzumab vedotin-piiq (anti-CD79b) (Ab175635) with the EC50 of 51.95 ng/mL.    
  4. Recombinant Mouse CD40/TNFRSF5 Protein
      种属: 小鼠(Mouse)    Accession #: P27512    
      表达系统: HEK293    蛋白标签: C-His    内毒素水平: <0.1 EU/μg    
      生物活性: Measured by its binding ability in a functional ELISA. When Recombinant Mouse CD40/TNFRSF5 is immobilized at 1 µg/mL (100 µL/well), the concentration of Recombinant Mouse CD40 Ligand/TNFSF5 that produces 50% optimal binding is found to be 100-600 ng/mL.    
  5. Recombinant Mouse IL-23R Protein
      种属: 小鼠(Mouse)    Accession #: Q8K4B4    
      表达系统: HEK293    蛋白标签: C-His    内毒素水平: <0.1 EU/μg    
      生物活性: Measured by its binding ability in a functional ELISA. When Recombinant Mouse IL-23 R is immobilized at 5 µg/mL (100 µL/well) the concentration of Recombinant Mouse IL‑23 that produces 50% of optimal binding response is approximately 5-25 ng/mL.    
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