Recombinant Human BCMA/TNFRSF17 Protein

COA

级别和纯度:

≥90%(SDS-PAGE)

表达系统: HEK293
Accession #: Q6PE46
蛋白标签: C-hFc
生物活性: Immobilized Recombinant Human BCMA/TNFRSF17 Protein (rp169554) at 0.5 μg/mL can bind Belantamab (anti-TNFRSF17) (Ab170526) with the EC50 of 22.0 ng/mL.
内毒素水平: <1.0 EU/μg

有货

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货号 (SKU)	包装规格	是否现货
rp169554-10μg	10μg	现货
rp169554-50μg	50μg	现货
rp169554-100μg	100μg	现货
rp169554-1mg	1mg	期货

查看相关系列

点击查看蛋白信息: TNFRSF17

Accession#: Q6PE46 (1) BCMA (5) BCMA/TNFRSF17 (1) Gene ID:608 (7) TNFRSF17 (7)

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基本描述

产品名称	Recombinant Human BCMA/TNFRSF17 Protein
别名	重组人BCMA/TNFRSF17蛋白 \| 重组人 BCMA/TNFRSF17 蛋白
英文别名	B cell maturation antigen \| B-cell maturation protein \| BCMA \| BCMAtumor necrosis factor receptor superfamily member 17 \| BCMB-cell maturation factor \| CD269 antigen \| CD269 \| TNFRSF13A \| TNFRSF17 \| tumor necrosis factor receptor superfamily, member 17,
规格或纯度	ActiBioPure™, Bioactive, Animal Free, Carrier Free, ≥90%(SDS-PAGE)
产品介绍	Protein Function: BCMA, B cell maturation antigen, is a member of the TNF receptor superfamily. It has been designated TNFRSF17. BCMA is a type III membrane protein containing one extracellular cysteine rich domain. Within the TNFRSF, it shares the highest homology with TACI. BCMA and TACI have both been shown to bind to APRIL and BAFF, members of the TNF ligand superfamily. BCMA expression has been found in immune organs and mature B cell lines. Although some expression has been observed at the cell surface, BCMA appears to be localized to the Golgi compartment. The binding of BCMA to APRIL or BAFF has been shown to stimulate IgM production in peripheral blood B cells and increase the survival of cultured B cells. This data suggests that BCMA may play an important role in B cell development, function and regulation. Human BCMA is a 184 amino acid (aa) protein consisting of a 54 aa extracellular domain, a 23 aa transmembrane domain, and a 107 aa intracellular domain. Mouse and human BCMA share 62% amino acid identity.
生物活性	Immobilized Recombinant Human BCMA/TNFRSF17 Protein (rp169554) at 0.5 μg/mL can bind Belantamab (anti-TNFRSF17) (Ab170526) with the EC50 of 22.0 ng/mL.
内毒素水平	<1.0 EU/μg
表达系统	HEK293
种属	人(Human)
氨基酸	1-54 aa
序列	MLQMAGQCSQNEYFDSLLHACIPCQLRCSSNTPPLTCQRYCNASVTNSVKGTNAIEGRMDPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
蛋白标签	C-hFc
无载体	Yes
无动物源	Yes
Accession #	Q6PE46
来源	重组表达
预测分子量	34.3 kDa
SDS-PAGE	34.0-44.3 kDa, under reducing conditions; 57.0-90.2 kDa, under non-reducing conditions

储存与运输

物理形态	冻干(Lyophilized)
储存缓冲液	Lyophilized from PBS, pH 7.4
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	在 -20°C 下可保存 1 年。避免冷冻/解冻循环。
分子类型	蛋白质

图片

ELISA: Recombinant Human BCMA/TNFRSF17 Protein (rp169554)

Recombinant Human BCMA/TNFRSF17 Protein (rp169554) - ELISA
Immobilized Recombinant Human BCMA/TNFRSF17 Protein (rp169554) at 0.5 μg/mL can bind Belantamab (anti-TNFRSF17) (Ab170526) with the EC50 of 22.0 ng/mL.

SDS-PAGE: Recombinant Human BCMA/TNFRSF17 Protein (rp169554)

Recombinant Human BCMA/TNFRSF17 Protein (rp169554) - SDS-PAGE
3 μg/lane of Recombinant Human BCMA/TNFRSF17 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 34.0-44.3 kDa under reducing conditions and 57.0-90.2 kDa under non-reducing conditions.

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找到3个结果

批号(Lot Number)	证书类型	货号
ZJ24F0707634	分析证书	rp169554
ZJ24F0707635	分析证书	rp169554
ZJ24F0707636	分析证书	rp169554

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