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Recombinant Mouse IL-1 RI Protein

  • 表达系统: HEK293
  • Accession #: P13504-1
  • 蛋白标签: C-His
  • 生物活性: Measured by its ability to inhibit IL-1 alpha -dependent proliferation in D10.G4.1 mouse helper T cells. Approximately 0.005‑0.015 µg/mL of IL-1 sRI will inhibit 50% of the biological response due to 50 pg/mL of rmIL-1a.
  • 内毒素水平: <0.1 EU/μg
有货

库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
rp154122-10μg
10μg 现货 Stock Image
rp154122-50μg
50μg 现货 Stock Image
rp154122-100μg
100μg 现货 Stock Image
rp154122-1mg
1mg 期货 Stock Image

基本描述

产品名称 Recombinant Mouse IL-1 RI Protein
别名 重组小鼠IL-1 RI蛋白 | 重组小鼠白介素1受体Ⅰ蛋白
英文别名 Interleukin 1 Receptor I | CD121 antigen-like family member A | CD121a antigen | CD121a | IL-1 RI | IL1R | IL1R1 | IL1RI | IL1RT1 | IL-1RT1 | IL-1RT-1 | Interleukin 1 Receptor 1 | interleukin 1 receptor, type I | interleukin receptor 1 | interleukin-1 rec
规格或纯度 ActiBioPure™, 生物活性, 无动物源, Carrier Free, High performance, ≥90%(SDS-PAGE)
产品介绍


Function
Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. Involved in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells.

生物活性 Measured by its ability to inhibit IL-1 alpha -dependent proliferation in D10.G4.1 mouse helper T cells. Approximately 0.005‑0.015 µg/mL of IL-1 sRI will inhibit 50% of the biological response due to 50 pg/mL of rmIL-1a.
内毒素水平 <0.1 EU/μg
表达系统 HEK293
种属 小鼠(Mouse)
氨基酸 20-338 aa
序列 LEIDVCTEYPNQIVLFLSVNEIDIRKCPLTPNKMHGDTIIWYKNDSKTPISADRDSRIHQQNEHLWFVPAKVEDSGYYYCIVRNSTYCLKTKVTVTVLENDPGLCYSTQATFPQRLHIAGDGSLVCPYVSYFKDENNELPEVQWYKNCKPLLLDNVSFFGVKDKLLVRNVAEEHRGDYICRMSYTFRGKQYPVTRVIQFITIDENKRDRPVILSPRNETIEADPGSMIQLICNVTGQFSDLVYWKWNGSEIEWNDPFLAEDYQFVEHPSTKRKYTLITTLNISEVKSQFYRYPFICVVKNTNIFESAHVQLIYPVPDFKHHHHHH
蛋白标签 C-His
无载体 Yes
无动物源 Yes
Accession # P13504-1
来源 重组表达
预测分子量 38.1kDa
SDS-PAGE 55-60 kDa under reducing conditions.

储存与运输

物理形态 冻干(Lyophilized)
储存缓冲液 Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH7.4.
复溶 Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 在 -20~-80℃ 下可保存 1 年以上。复溶后建议分装。避免冷冻/解冻循环。
分子类型 蛋白质

图片

Recombinant Mouse IL-1 RI Protein (rp154122) - SDS-PAGE
2 μg/lane of Recombinant Mouse IL-1 RI Protein was resolved with SDS-PAGE under reducing (R) conditions and visualized by Coomassie® Blue staining, showing the band at 50 - 55 kDa under reducing conditions.

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批号(Lot Number) 证书类型 货号
ZJ25F0522120 分析证书 rp154122
ZJ25F0522119 分析证书 rp154122
ZJ25F0522118 分析证书 rp154122

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