Recombinant Human TL1A/TNFSF15 Protein

COA

级别和纯度:

≥90%(SDS-PAGE)

表达系统: E. coli
Accession #: O95150
蛋白标签: No tag
生物活性: Measured by its ability to induce apoptosis of TF1 human erythroleukemic cells.The ED50 for this effect is typically 1.15 ng/mL.
内毒素水平: <1.0 EU/μg

有货

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货号 (SKU)	包装规格	是否现货
rp170417-10μg	10μg	现货
rp170417-50μg	50μg	现货
rp170417-100μg	100μg	现货
rp170417-1mg	1mg	期货

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点击查看蛋白信息: TNFSF15

Accession#:O95150 (1) Gene ID:9966 (1) TL1A/TNFSF15 (1) TNFSF15 (1)

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基本描述

产品名称	Recombinant Human TL1A/TNFSF15 Protein
别名	重组人TL1A/TNFSF15蛋白 \| 重组人TL1A/TNFSF15蛋白 \| 重组人 TL1A/TNFSF15 蛋白
英文别名	MGC129934 \| MGC129935 \| TL1A \| TL1Vascular endothelial cell growth inhibitor \| TNF superfamily ligand TL1A \| TNFSF15 \| tumor necrosis factor (ligand) superfamily, member 15 \| tumor necrosis factor ligand superfamily member 15 \| vascular endothelial growth
规格或纯度	Carrier Free, 生物活性, High performance, ActiBioPure™, ≥90%(SDS-PAGE)
产品介绍	Protein Function: TL1A, also known as TNFSF15, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is specifically expressed in endothelial cells. TL1A also can be detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon. TL1A is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It mediates activation of NF-kappa-B. It also inhibits vascular endothelial growth and angiogenesis (in vitro). TL1A promotes activation of caspases and apoptosis. It is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor.
生物活性	Measured by its ability to induce apoptosis of TF1 human erythroleukemic cells.The ED50 for this effect is typically 1.15 ng/mL.
内毒素水平	<1.0 EU/μg
表达系统	E. coli
种属	人(Human)
氨基酸	72-251 aa
序列	LKGQEFAPSHQQVYAPLRADGDKPRAHLTVVRQTPTQHFKNQFPALHWEHELGLAFTKNRMNYTNKFLLIPESGDYFIYSQVTFRGMTSECSEIRQAGRPNKPDSITVVITKVTDSYPEPTQLLMGTKSVCEVGSNWFQPIYLGAMFSLQEGDKLMVNVSDISLVDYTKEDKTFFGAFLL
蛋白标签	No tag
无载体	Yes
无动物源	No
Accession #	O95150
来源	重组表达
预测分子量	20.4 kDa
SDS-PAGE	20.5 kDa, under reducing conditions

储存与运输

物理形态	冻干(Lyophilized)
储存缓冲液	Lyophilized from PBS, 0.02% Tween 80, pH 7.4
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.5 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	在 -20°C 下可保存 1 年。避免冷冻/解冻循环。
分子类型	蛋白质

图片

Protein Bioactivity: Recombinant Human TL1A/TNFSF15 Protein (rp170417)

Recombinant Human TL1A/TNFSF15 Protein (rp170417) - Protein Bioactivity
Measured by its ability to induce apoptosis of TF1 human erythroleukemic cells.The ED₅₀ for this effect is typically 1.15 ng/mL.

SDS-PAGE: Recombinant Human TL1A/TNFSF15 Protein (rp170417)

Recombinant Human TL1A/TNFSF15 Protein (rp170417) - SDS-PAGE
3 μg/lane of Recombinant Human TL1A/TNFSF15 Protein was resolved with SDS-PAGE under reducing (R) conditions and visualized by Coomassie® Blue staining, showing a band at 20.5 kDa under reducing conditions.

Protein Bioactivity: Recombinant Human TL1A/TNFSF15 Protein (rp170417)

Recombinant Human TL1A/TNFSF15 Protein (rp170417) - Protein Bioactivity
TF-1 cells were co-stimulated with 10 μg/mL CHX (C112766) and 200 ng/mL Recombinant Human TL1A/TNFSF15 Protein (rp170417) for 24 hours. Cells were then stained with Annexin V-FITC/PI Apoptosis Detection Kit (A266226) and analyzed by FACS.

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找到3个结果

批号(Lot Number)	证书类型	货号
ZJ24F1011736	分析证书	rp170417
ZJ24F1011735	分析证书	rp170417
ZJ24F1011734	分析证书	rp170417

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