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ADC药物研发(ADCs)

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  1. Recombinant Human CD276 Protein
      种属: 人(Human)    Accession #: Q5ZPR3-2    
      表达系统: HEK293    蛋白标签: C-His    内毒素水平: <0.1 EU/μg    
      生物活性: 1、Immobilized Recombinant Human CD276 Protein (rp143912) at 0.5 μg/mL can bind Anti Human CD276 Antibody with the EC50 of 10.73 ng/mL. 2、Immobilized Recombinant Human CD276 Protein (rp143912) at 1 μg/mL can bind Anti Human CD276 Antibody with a linear range of 1 - 4 ng/mL (EC50:4.3 ng/mL).    
  2. Recombinant Human B7-H3(4Ig)/B7-H3b Protein
      种属: 人(Human)    Accession #: Q5ZPR3    
      表达系统: HEK293    蛋白标签: C-His    内毒素水平: <1.0 EU/μg    
      生物活性: 1、Measured by its binding ability in a functional ELISA. Immobilized CD276 mouse mAb at 1.0 μg/mL can bind Recombinant Human B7-H3 (4Ig)/B7-H3b Protein (rp176244) with the EC50 of 51.95 ng/mL. 2、Measured by its binding ability in a functional ELISA. Immobilized human Human B7-H3 (4Ig)/B7-H3b (rp176244) at 1.0 μg/mL can bind CD276 mouse mAb with the EC50 of 1.86 ng/mL.    
  3. Recombinant Human Siglec-2/CD22 Protein
      种属: 人(Human)    Accession #: P20273    
      表达系统: HEK293    蛋白标签: C-His    内毒素水平: <1.0 EU/μg    
      生物活性: Immobilized Recombinant Human Siglec-2/CD22 Protein (rp169575) at 1.0 μg/mL can bind Inotuzumab (anti-CD22) (Ab176429) with the EC50 of 20.1 ng/mL.  Immobilized Recombinant Human Siglec-2/CD22 Protein (rp169575) at 1.0 μg/mL can bind bind Epratuzumab (anti-CD22) (Ab175532) with the EC50 of 207.0 ng/mL.    
  4. Recombinant Human EGFR Isoform vIII Protein
      种属: 人(Human)    Accession #: NP_001333870.1    
      表达系统: HEK293    蛋白标签: C-His    内毒素水平: <1.0 EU/μg    
      生物活性: Immobilized Recombinant Human EGFR Isoform vIII Protein (rp176275) at 1.0 μg/mL can bind Depatuxizumab mafodotin (anti-EGFR) (Ab175508) with the EC50 of 19.11 ng/mL. Immobilized Recombinant Human EGFR Isoform vIII Protein (rp176275) at 1.0 μg/mL can bind Depatuxizumab (anti-EGFR) (Ab182750) with the EC50 of 22.53 ng/mL.    
  5. Recombinant Human Glypican 3 Protein
      种属: 人(Human)    Accession #: P51654-1    
      表达系统: HEK293    蛋白标签: C-His    内毒素水平: <1.0 EU/μg    
      生物活性: Immobilized Recombinant Human Glypican 3 Protein (rp176299) at 4.0 μg/mL can bind Recombinant Human FGF basic Protein (rp156010) with the EC50 of 441.4 ng/mL. Immobilized Recombinant Human FGF basic Protein (rp156010) at 1.0 μg/mL can bind Recombinant Human Glypican 3 Protein (rp176299) with the EC50 of 7.4 ng/mL.    
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