Recombinant Human ROR1 Protein

COA

级别和纯度:

≥95%(SDS-PAGE)

表达系统: HEK293
Accession #: Q01973
蛋白标签: C-His
生物活性: Immobilized Recombinant Human ROR1 Protein (rp176297) at 2.0 μg/mL can bind Zilovertamab (anti-ROR1) (Ab170644) , the EC50 is 16.07 ng/mL.
内毒素水平: <1.0 EU/μg

有货

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货号 (SKU)	包装规格	是否现货
rp176297-10μg	10μg	现货
rp176297-50μg	50μg	现货
rp176297-100μg	100μg	现货
rp176297-1mg	1mg	期货

查看相关系列

点击查看蛋白信息: ROR1

Accession#:Q01973 (3) Gene ID:4919 (3) ROR1 (3)

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基本描述

产品名称	Recombinant Human ROR1 Protein
别名	重组人ROR1蛋白 \| 重组人类ROR1蛋白
英文别名	dJ537F10.1 \| Inactive tyrosine protein kinase transmembrane receptor ROR1 \| MGC99659 \| Neurotrophic tyrosine kinase \| Neurotrophic tyrosine kinase receptor related 1 \| Neurotrophic tyrosine kinase, receptor related 1 \| NTRKR1 \| OTTHUMP00000010573 \| OTTHUM
规格或纯度	ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, ≥95%(SDS-PAGE)
产品介绍	Purity:>95%, by SDS-PAGE visualized with Coomassie® Blue Staining Description: ROR1 (Receptor tyrosine kinase-like orphan receptor 1), also known as neurotrophic tyrosine kinase receptor-related 1 (NTRKR1), is a member of the ROR family within the receptor tyrosine kinases (RTK) superfamily. Two ROR family members (ROR1 and ROR2) have been identified and are characterized by their intracellular tyrosine kinase domains, which are highly related to those of the Trk-family receptor tyrosine kinases, and by their extracellular Frizzled-like cysteine-rich domains and kringle domains, common to receptors of the Wnt family members. Human ROR1 is a type I transmembrane protein with 937 amino acids in length. It contains a 29 amino acid signal sequence, a 377 amino acid extracellular domain (ECD), a 21 amino acid transmembrane segment, and a 510 amino acid cytoplasmic region. Human ROR1 shares 97% and 58% amino acid sequence identity with mouse ROR1 and human ROR2, respectively. ROR1 has been shown to play crucial roles in developmental morphogenesis by acting as receptors or co-receptors to mediate Wnt5a-induced signaling. The bioactivity of ROR1 is measured by its ability to bind biotinylated recombinant mouse Wnt-5a in a functional ELISA.
生物活性	Immobilized Recombinant Human ROR1 Protein (rp176297) at 2.0 μg/mL can bind Zilovertamab (anti-ROR1) (Ab170644) , the EC50 is 16.07 ng/mL.
内毒素水平	<1.0 EU/μg
表达系统	HEK293
种属	人(Human)
氨基酸	1-403 aa
序列	MHRPRRRGTRPPLLALLAALLLAARGAAAQETELSVSAELVPTSSWNISSELNKDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEEDGFCQPYRGIACARFIGNRTVYMESLHMQGEIENQITAAFTMIGTSSHLSDKCSQFAIPSLCHYAFPYCDETSSVPKPRDLCRDECEILENVLCQTEYIFARSNPMILMRLKLPNCEDLPQPESPEAANCIRIGIPMADPINKNHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEAPWCFTLDENFKSDLCDIPACDSKDSKEKNKMEHHHHHH
纯度	>95% (SDS-PAGE)
蛋白标签	C-His
无载体	Yes
无动物源	Yes
Accession #	Q01973
来源	重组表达
预测分子量	42.8 kDa
SDS-PAGE	56.7-66.3 kDa, under reducing conditions; 52.4-61.0 kDa, under non-reducing condition

储存与运输

物理形态	冻干(Lyophilized)
储存缓冲液	Lyophilized from PBS, pH7.4
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	在 -20°C 下可稳定保存 1 年。避免冷冻/解冻循环。
分子类型	蛋白质

图片

ELISA: Recombinant Human ROR1 Protein (rp176297)

Recombinant Human ROR1 Protein (rp176297) - ELISA
Immobilized Recombinant Human ROR1 Protein (rp176297) at 2.0 μg/mL can bind Zilovertamab (anti-ROR1) (Ab170644), the EC₅₀ is 16.07 ng/mL.

SDS-PAGE: Recombinant Human ROR1 Protein (rp176297)

Recombinant Human ROR1 Protein (rp176297) - SDS-PAGE
3 μg/lane of Recombinant Human ROR1 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 56.7-66.3 kDa under reducing conditions and 52.4-61.0 kDa under non-reducing conditions.

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找到3个结果

批号(Lot Number)	证书类型	货号
ZJ24F0303306	分析证书	rp176297
ZJ24F0303307	分析证书	rp176297
ZJ24F0303308	分析证书	rp176297

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