基本信息

产品名称	Recombinant CD16 Antibody (AF700)
别名	白细胞分化抗原16 \| FC段γ受体3/免疫球蛋白G Fc段受体III单克隆抗体 \| Anti-CD16抗体 \| CD16抗体
英文别名	CD16 \| CD16A \| Fc fragment of IgG receptor IIIa \| Fc gamma RIII \| FCG3 \| FCGR3 \| FcgRIII \| FCR-10 \| FCRIII \| FCRIIIA \| IGFR3 \| IMD20 \| CD 16 antibody \| CD 16a antibody \| CD16 antibody \| CD16a antibody \| CD16a antigen antibody \| CD16B antibody \| CD16b anti
规格或纯度	ExactAb™, 已验证, 5 μL/test
生化机理	Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.
宿主种属	小鼠(Mouse)
特异性	Human CD16
种属反应性	人(Human)
免疫原	Human polymorphonuclear leukocytes.
阳性对照	Flow Cytometry: Human peripheral blood lymphocytes.
偶联	AF700
Excitation(nm)	Red Laser(633nm)
Emission(nm)	719nm
Ex/Em(nm)	Ex:696nm;Em:719nm

产品属性

克隆类型	重组抗体
Format	Whole IgG
轻链亚型	kappa
纯化方法	Protein A purified
储存缓冲液	Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.
防腐剂	0.05% Proclin300
浓度	5 μL/test
储存温度	2-8°C储存,避光,禁止冷冻
运输条件	冰袋运输
稳定性与储存	The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
分子类型	抗体

关联靶点（人）

FCGR3A Tclin 低亲和力免疫球蛋白γFc区受体III-A(Low affinity immunoglobulin gamma Fc region receptor III-A) (0 活性数据)

点击查看靶蛋白信息： FCGR3A

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

图片

Flow Cytometry: Recombinant CD16 Antibody (AF700) (Ab216117)

Recombinant CD16 Antibody (AF700) (Ab216117) - Flow Cytometry
Flow cytometry analysis of CD16 expression by human peripheral blood lymphocytes (right panel) compared to an isotype control (left panel). Cells were stained with Recombinant CD16 Antibody (AF700) (Ab216117) at 5μL/test for 1 hour at 4°C. Left panel - Mouse IgG (AF700) (Ab190248).

Flow Cytometry: Recombinant CD16 Antibody (AF700) (Ab216117)

Recombinant CD16 Antibody (AF700) (Ab216117) - Flow Cytometry
Flow cytometry analysis of CD16 expression by human peripheral blood lymphocytes (red) compared to an isotype control (blue). Cells were stained with Recombinant CD16 Antibody (AF700) (Ab216117) at 5μL/test for 1 hour at 4°C. Blue - Mouse IgG (AF700) (Ab190248). Black - Unlabelled control, cells without incubation with primary antibody.

应用

应用名称	稀释比例
Flow Cytometry	5 μL/test. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood.