基本信息

产品名称	Recombinant CD16 Antibody
别名	白细胞分化抗原16 \| FC段γ受体3/免疫球蛋白G Fc段受体III单克隆抗体 \| Anti-CD16抗体 \| CD16抗体
英文别名	CD16 \| CD16A \| Fc fragment of IgG receptor IIIa \| Fc gamma RIII \| FCG3 \| FCGR3 \| FcgRIII \| FCR-10 \| FCRIII \| FCRIIIA \| IGFR3 \| IMD20 \| CD 16 antibody \| CD 16a antibody \| CD16 antibody \| CD16a antibody \| CD16a antigen antibody \| CD16B antibody \| CD16b anti
规格或纯度	无动物源, 无载体, 重组, ExactAb™, 无叠氮钠, 已验证, 高性能, ≥95%(SDS-PAGE), 见COA
生化机理	Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.
宿主种属	小鼠(Mouse)
特异性	Human CD16
种属反应性	人(Human)
免疫原	Human polymorphonuclear leukocytes
阳性对照	Flow Cytometry: Human peripheral blood lymphocytes
偶联	Unconjugated

产品属性

克隆类型	重组抗体
Format	Whole IgG
轻链亚型	kappa
SDS-PAGE	150 kDa
纯化方法	Protein A purified
储存缓冲液	PBS, pH 7.4
浓度	见COA
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	Store at 4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
分子类型	抗体

关联靶点（人）

FCGR3A Tclin 低亲和力免疫球蛋白γFc区受体III-A(Low affinity immunoglobulin gamma Fc region receptor III-A) (0 活性数据)

点击查看靶蛋白信息： FCGR3A

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

图片

Flow Cytometry: Recombinant CD16 Antibody (Ab212149)

Recombinant CD16 Antibody (Ab212149) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD16 with Recombinant CD16 Antibody (Ab212149) conjugated with biotin (right panel) at 0.2 μg/mL for 1 hour at 4°C, compared with Mouse IgG (Biotin) (Ab180306) - Isotype Control (left panel) and detected with SA-PE (rp156150).

Flow Cytometry: Recombinant CD16 Antibody (Ab212149)

Recombinant CD16 Antibody (Ab212149) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD16 (red) with Recombinant CD16 Antibody (Ab212149) conjugated with biotin at 0.2 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Isotype control, mouse IgG (Ab180306) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.