基本信息

产品名称	CD11b Mouse mAb (AF405)
别名	整合素αM(CD11b)抗体 \| CD11b抗体 \| AF405-CD11b抗体
英文别名	CD11B \| antigen CD11b (p170) \| CD11 antigen-like family member B \| CD11b antigen \| Cell surface glycoprotein MAC-1 subunit alpha \| Complement component 3 receptor 3 subunit \| CR-3 alpha chain \| CR3A \| CR3AMGC117044 \| Integrin alpha M \| integrin alpha-M \|
规格或纯度	ExactAb™, 已验证, Ex:401nm, Em:422nm, 5 μL/test
生化机理	Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
宿主种属	小鼠(Mouse)
特异性	CD11b
种属反应性	人(Human)
免疫原	Rheumatoid synovial cells and human monocytes.
阳性对照	Flow: Human peripheral blood monocytes
偶联	AF405
Excitation(nm)	Violet Laser(405nm)
Emission(nm)	422nm
Ex/Em(nm)	Ex:401nm;Em:422nm

产品属性

克隆类型	单克隆抗体
Format	Whole IgG
轻链亚型	kappa
SDS-PAGE	150 kDa
纯化方法	Protein G purified
储存缓冲液	Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.
防腐剂	0.05% Proclin300
浓度	5 μL/test
储存温度	2-8°C储存,避光,禁止冷冻
运输条件	冰袋运输
稳定性与储存	The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
分子类型	抗体

关联靶点（人）

ITGAM Tbio 整合素α-M(Integrin alpha-M) (0 活性数据)

点击查看靶蛋白信息： ITGAM

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

图片

Flow Cytometry: CD11b Mouse mAb (AF405) (Ab191609)

CD11b Mouse mAb (AF405) (Ab191609) - Flow Cytometry
Flow cytometry analysis of CD11b expression by human peripheral blood (right panel) compared to an isotype control (left panel). Cells were stained with CD11b Mouse mAb (AF405) (Ab191609) at 5μL/test for 1 hour at 4°C. Left panel - Mouse IgG (AF405) (Ab190076).

Flow Cytometry: CD11b Mouse mAb (AF405) (Ab191609)

CD11b Mouse mAb (AF405) (Ab191609) - Flow Cytometry
Flow cytometry analysis of CD11b expression by human peripheral blood monocytes (red) compared to an isotype control (blue). Cells were stained with CD11b Mouse mAb (AF405) (Ab191609) at 5μL/test for 1 hour at 4°C. Blue - Mouse IgG (AF405) (Ab190076). Black - Unlabelled control, cells without incubation with primary antibody.

应用

应用名称	稀释比例
Flow Cytometry	5 μL/test, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood

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找到3个结果

批号(Lot Number)	证书类型	货号
ZJ24F1113440	分析证书	Ab191609
ZJ24F1113441	分析证书	Ab191609
ZJ24F1113442	分析证书	Ab191609

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