SOX17 Mouse mAb

COA

级别和纯度:

已验证

ExactAb™

高性能

见COA

应用:

IF/ICC
WB

宿主种属: 小鼠(Mouse)
种属反应性: 人(Human), 大鼠(Rat), 小鼠(Mouse), 狗(Dog)
亚型: Mouse IgG2a
克隆号: OTI3H5
偶联: Unconjugated

有货

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货号 (SKU)	包装规格	是否现货
Ab128771-10μl	10μl	现货
Ab128771-50μl	50μL	现货
Ab128771-100μl	100μL	现货
Ab128771-1ml	1ml	期货

查看相关系列

点击查看靶蛋白信息: SOX17

Accession#: Q9H6I2 (1) Gene ID: 64321 (1) SOX17 (1) VUR3 (1)

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基本信息

产品名称	SOX17 Mouse mAb
别名	Anti-SOX17 抗体 \| SOX17 抗体 \| SOX17 单克隆抗体
英文别名	FLJ22252 \| SOX17 \| SRY (sex determining region Y)-box 17 \| SRY-related HMG-box transcription factor SOX17 \| transcription factor SOX-17 \| VUR3 \| FLJ22252 antibody \| SOX17 antibody \| SOX17_HUMAN antibody \| SRY (sex determining region Y) box 17 antibody \| S
规格或纯度	ExactAb™, 已验证, 高性能, 见COA
生化机理	Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'-AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells.
宿主种属	小鼠(Mouse)
特异性	SOX17
种属反应性	人(Human),大鼠(Rat),小鼠(Mouse),狗(Dog)
免疫原	Recombinant protein of human SOX17 (AA 177-414)
阳性对照	WB: HeLa, HT-29, A549, MCF7 and Hep G2 cell lysates. IF/ICC: COS7cells transiently transfected with pCMV6-ENTRY SOX17.
偶联	Unconjugated

产品属性

克隆类型	单克隆抗体
Format	Whole IgG
SDS-PAGE	150 kDa
纯化方法	Protein A purified
物理外观	Liquid
储存缓冲液	10mM PBS, 50% Glycerol, 1% BSA, 0.02% Sodium azide, pH 7.3.
防腐剂	0.02% Sodium azide
浓度	见COA
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
分子类型	抗体

关联靶点（人）

SOX17 Tbio 转录因子 SOX-17(Transcription factor SOX-17) (0 活性数据)

点击查看靶蛋白信息： SOX17

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

图片

Western Blot: SOX17 Mouse mAb (Ab128771)

SOX17 Mouse mAb (Ab128771) - Western Blot
All lanes: SOX17 Mouse mAb (Ab128771) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab179001) at 1/10000 dilution

Predicted band size: 44 kDa
Observed band size: 49 kDa
Exposure time: 1.9 s

IF/ICC: SOX17 Mouse mAb (Ab128771)

SOX17 Mouse mAb (Ab128771) - IF/ICC
SOX17 Mouse mAb (Ab128771) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SOX17.