HSC70 Mouse mAb

COA

级别和纯度:

已验证

ExactAb™

见COA

应用:

宿主种属: 小鼠(Mouse)
种属反应性: 人(Human), 大鼠(Rat), 小鼠(Mouse)
亚型: Mouse IgG1
克隆号: 7G12
偶联: Unconjugated

有货

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货号 (SKU)	包装规格	是否现货
Ab108717-10μl	10μl	现货
Ab108717-50μl	50μL	现货
Ab108717-100μl	100μL	期货
Ab108717-1ml	1ml	期货

查看相关系列

点击查看靶蛋白信息: HSPA8

Accession#: P11142 (2) Gene ID: 3312 (2) Hsc70 (1) HSC71 (1) HSPA8 (2)

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基本信息

产品名称	HSC70 Mouse mAb
别名	热休克蛋白71抗体 \| 热休克蛋白71单克隆抗体 \| HSC70抗体 \| HSC70单克隆抗体 \| HSPA8抗体 \| HSPA8单克隆抗体
英文别名	2410008N15Rik antibody \| Constitutive heat shock protein 70 antibody \| Epididymis luminal protein 33 antibody \| Epididymis secretory sperm binding protein Li 72p antibody \| Heat shock 70 kDa protein 8 antibody \| Heat shock 70kD protein 10 antibody \| Heat
规格或纯度	ExactAb™, 已验证, 见COA
生化机理	Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Isoform 2 may function as an endogenous inhibitory regulator of HSC70 by competing the co-chaperones. Post-translational: Phosphorylated upon DNA damage, probably by ATM or ATR. ISGylated.
宿主种属	小鼠(Mouse)
特异性	HSPA8
种属反应性	人(Human),大鼠(Rat),小鼠(Mouse)
免疫原	A synthetic peptide derived from human HSC70.
阳性对照	WB: Mouse brain, HeLa, A431, A549, U-2 OS, NIH/3T3 and C6 lysates. IHC: Human brain, breast carnimona, tonsil tissues.
偶联	Unconjugated

产品属性

克隆类型	单克隆抗体
克隆号	7G12
Format	Whole IgG
亚型	Mouse IgG1
SDS-PAGE	150 kDa
纯化方法	Immunogen affinity purified
物理外观	Liquid
储存缓冲液	10mM PBS, 50% Glycerol, 0.5% BSA, 0.02% Sodium azide, pH 7.4.
防腐剂	0.02% Sodium azide
浓度	见COA
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	-20℃长期保存（12 个月）。收货后建议分装。避免冷冻/解冻循环。
分子类型	抗体

关联靶点（人）

HSPA8 Tchem 热休克同源 71 kDa 蛋白(Heat shock cognate 71 kDa protein) (0 活性数据)

点击查看靶蛋白信息： HSPA8

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

图片

Western Blot: HSC70 Mouse mAb (Ab108717)

HSC70 Mouse mAb (Ab108717) - Western Blot
All lanes: HSC70 Mouse mAb (Ab108717) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab179001) at 1/20000 dilution
Predicted band size: 71 kDa
Observed band size: 73 kDa
Exposure time: 50.9 s

IHC: HSC70 Mouse mAb (Ab108717)

HSC70 Mouse mAb (Ab108717) - IHC
Immunohistochemical analysis of paraffin-embedded Human Brain Tissue using HSC70 Mouse mAb (Ab108717) diluted at 1/200.

IHC: HSC70 Mouse mAb (Ab108717)

HSC70 Mouse mAb (Ab108717) - IHC
Immunohistochemical analysis of paraffin-embedded Human Tonsil Tissue using HSC70 Mouse mAb (Ab108717) diluted at 1/200.

IHC: HSC70 Mouse mAb (Ab108717)

HSC70 Mouse mAb (Ab108717) - IHC
Immunohistochemical analysis of paraffin-embedded Human Breast Carnimona Tissue using HSC70 Mouse mAb (Ab108717) diluted at 1/200.